ANTIBIOTICS

HISTORY OF
ANTIBIOTICS
Historical Timeline
📌 1920s- Protonsil (the first sulphonamide) is discovered by
Jose Klarer, Fritz Mietzsch, and Gerhard
Domagk.
📌 1928- Alexander Fleming discovered Penicillin.
📌 1931- Penicillin-soaked cloth is used to cure eye and skin
infection.
📌 1939- First antibiotic (tyrothricin) to work in a mouse is
discovered by Rene Dubos.
📌 1941- Penicillin starts to save man from rose bush infection
and Penicillin is mass produced.
Historical Timeline
📌 1920s- Protonsil (the first sulphonamide) is discovered by
Jose Klarer, Fritz Mietzsch, and Gerhard Domagk.
📌 1928- Alexander Fleming discovered Penicillin.
📌 1931- Penicillin-soaked cloth is used to cure eye and skin
infection.
📌 1939- First antibiotic (tyrothricin) to work in a mouse is
discovered by Rene Dubos.
📌 1941- Penicillin starts to save man from rose bush infection
and Penicillin is mass produced.
Historical Timeline
📌 1976- Carbapenems was discovered and it is the “new last
resort” drug to treat resistant bacteria.
📌 1997- Link between drug resistant bacteria in animals and in
humans is clearer.
📌 📌
2002-2012- There were many issues about the MRSA bacteria
that caused many deaths among human beings. It was not
enough to kill that certain bacteria.
📌 2014- WHO published its first report on the global status of
antimicrobial resistance.
📌 2015- Teixobactin, a new antibiotic with a promising ability to
avoid resistance was discovered using soil.
 Uses
 To prevent infection
 Medical conditions: diabetes
 Common illnesses: cough, colds

An antibiotic is given for the treatment of an infection caused by bacteria. It is not effective against viruses.
disadvantages
& advantages
 ADVANTAGES
- Combat various diseases
which are caused by the
harmful microorganisms
- Do not harm other normal
cells.
-Macrolide antibiotics are
strongly germ killing
- Low effects of
gastrointestinal side effects
DISADVANTAGES
- Overuse contributes to
the increase in the bacterial
infections
- Bacteria becoming
resistant to the anitbiotic
- Kills the healthy bacteria
in the body
- Disrupt microfauna and
microflora.
examples
PENICILLIN
AMOXICILLIN
THANKS!
Any questions?
SOURCES
https://www.medicalnewstoday.com/articles/10278.php
https://www.online-sciences.com/health/antibiotics-advantages-
and-disadvantages/
http://antibiotic-action.com/wp-content/uploads/2016/05/short-
history-of-abx-fun-facts-flattened-25.04.2016.pdf