DIABETES MELITUS

ILMU PENYAKIT DALAM RSUD KARDINAH

DEFINISI
APA ITU DIABETES MELITUS?
Diabetes adalah penyakit kronis serius yang
terjadi karena pankreas tidak menghasilkan
cukup insulin (hormon yang mengatur gula
darah atau glukosa), atau ketika tubuh tidak
dapat secara efektif menggunakan insulin yang
dihasilkannya.
 TIPE DIABETES

Insulin dependent atau DIABETES TIPE 2

juvenile / childhood-onset
diabetes ditandai dengan
kurangnya produksi
insulin
DIABETES TIPE 1
Non-insulin-dependent
atau adult-onset
diabetes disebabkan
penggunaan insulin
yang kurang efektif
TIPE DIABETES LAINNYA
DIABETES GESTASIONAL
01 Hiperglikemi yang didapatkan saat kehamilan

02 TOLERANSI GLUKOSA TERGANGGU (TGT)

GLUKOSA DARAH PUASA TERGANGGU

03 (GDP TERGANGGU)

TGT dan GDP Terganggu merupakan kondisi transisi antara

normal dan diabetes, yang beresiko tinggi menjadi diabetes
mellitus tipe 2 .
EPIDEMIOLOGI DI INDONESIA

Riset Kesehatan Dasar (RISKESDAS) tahun 2007 dan 2013 pada usia 15 tahun keatas,
di definisikan sebagai diabetes melitus jika pernah di diagnosis menderita kencing
manis oleh dokter atau belum pernah di diagnosis menderita kencing manis oleh
dokter tetapi dalam 1 bulan terakhir mengalami gejala sering lapar, sering haus, serig
buang air kecil dengan jumlah banyak dan berat badan turun.

Sumber: Riskesdas 2007, 2013 Kementerian Kesehatan

EPIDEMIOLOGI DI DUNIA
PREVALENSI JUMLAH (JUTA)
REGIONAL 1980 2014 1980 2014
Afrika 3,1 7,1 4 25
Amerika 5,0 8,3 18 62
Mediterania 5,9 13,7 6 43
Timur
Eropa 5,3 7,3 33 64
Asia Tenggara 4,1 8,6 17 96

Pasifik Barat 4,4 8,4 29 131

Total 4,7 8,5 108 422

Dewasa usia > 18 tahun, jumlah terbesar orang dengan diabetes berasal dari Asia Tenggara dan
Pasifik Barat

Infodatin: Pusat dan Informasi Kementerian Kesehatan RI

 FAKTOR RESIKO
TIDAK DAPAT DI MODIFIKASI DAPAT DI MODFIKASI
• Ras dan etnik • Berat badan lebih
Get a modern
• Umur PowerPoint • Obesitas
• Jenis Kelamin Presentation that
is beautifully
abdominal/sentral
• Riwayat keluarga dengan designed. • Kurangnya aktivitas fisik
diabetes • Hipertensi
• Riwayat melahirkan bayi • Dislipidemia
dengan berat badan > • Diet tidak sehat/tidak
4000 gram seimbang
• Riwayat lahir dengan • Riwayat toleransi glukosa
berat badan lahir rendah terganggu (TGT)
< 2500 gram • Riwayat Glukosa Darah
Puasa Terganggu
• Merokok
 GEJALA KLASIK

Mudah Lapar
GEJALA LAIN

Sering gatal terutama

pada kemaluan
 KRITERIA DIAGNOSIS
American Diabetes Association (ADA) 2011 dan Konsesus
Perkumpulan Endokrinologi Indonesia (PERKENI) 2011 :

Glukosa plasma puasa ≥ 126 mg/dl dengan

01
gejala klasik penyerta

Glukosa 2 jam pasca pembebanan ≥ 200

02
mg/dl

Glukosa plasma sewaktu ≥200 mg/dl bila terdapat keluhan

klasik DM seperti banyak kencing (poliuria), banyak minum
03
(polidipsia), banyak makan (polifagia), dan penurunan
berat badan yang tidak dapat dijelaskan penyebabnya
 KRITERIA
DIAGNOSIS

Kriteria diagnosis DM (konsensus PERKENI 2015) :

• Pemeriksaan glukosa plasma puasa ≥126 mg/dl. Puasa adalah kondisi tidak ada
asupan kalori minimal 8 jam, atau
• Pemeriksaan glukosa plasma ≥200 mg/dl 2 jam setelah Tes Toleransi Glukosa
Oral (TTGO) dengan beban glukosa 75 gram, atau
• Pemeriksaan glukosa plasma sewaktu ≥200 mg/dl dengan keluhan klasik
(poliuria, polidipsia, polifagia dan penurunan berat badan yang tidak dapat
dijelaskan sebabnya), atau
• Pemeriksaan HbA1c ≥6,5% dengan menggunakan metode yang terstandarisasi
oleh National Glycohaemoglobin Standarization Program (NGSP).
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You can simply impress your audience and
add a unique zing and appeal to your
Presentations. Easy to change colors,
photos and Text. You can simply impress
Two your audience and add a unique zing and
appeal to your Presentations. Easy to
change colors, photos and Text. I hope and
Columns I believe that this Template will your Time,
Money and Reputation.
Easy to change colors, photos and Text. I
hope and I believe that this Template will
your Time, Money and Reputation. You
can simply impress your audience and add
a unique zing and appeal to your
Presentations.
I hope and I believe that this Template will
your Time, Money and Reputation.
You can simply impress your audience and
add a unique zing and appeal to your
Presentations. Easy to change colors,
photos and Text. You can simply impress
your audience and add a unique zing and
appeal to your Presentations. Easy to
change colors, photos and Text. I hope and
I believe that this Template will your Time,
Money and Reputation.
You can simply impress your audience and
add a unique zing and appeal to your
Presentations. Easy to change colors,
photos and Text. I hope and I believe that
this Template will your Time, Money and
Reputation.
You can simply impress your audience and
add a unique zing and appeal to your
Presentations. Easy to change colors,
photos and Text. I hope and I believe that
this Template will your Time, Money and
Reputation.
You can simply impress your audience and
add a unique zing and appeal to your
Presentations.
You can simply impress your audience and
add a unique zing and appeal to your
Presentations.
Thank you
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