Anda di halaman 1dari 18

Fumonisin in

Soybeans
Kelompok 2

Problem Set #3
1. The hazard and risk
The possibility mycotoxin contamination in related food product, how
about hazard characteristic?, how to analyze the hazard, and any
availability of toxicological data?
2. The communities
Who might be harmed? Any outbreak report? How big the case is?
3. The hazard control
How the effectiveness of control methods ?, how about the good
practices along the food chain?, how about the standard set by
legislator?
4. Preparedness of risk assessment
Any other steps needed to risk assessment study?
Possibility fumonisin contamination in
Soybeans

Kontaminasi di lahan Kontaminasi di penyimpanan

Faktor yang mempengaruhi


kontaminasi fumonisin :
• Ketersedian nutrisi
• Kadar air biji kedelai
• Suhu dan RH lingkungan saat
panen dan penyimpanan
• Lama penyimpanan
Kontaminasi di gudang
penyimpanan
Characteristic of Fumonisin
Dose-response Total
PMTDI(provisional 2 µg/kg body weight –
Karsinogenik, maximum WHO/FAO
neurotoksik,
tolerated daily
hepatotoksik
, imunotoksik intake)
NOEL 0.2 mg/kg bw / day
LOEL 0.62 µg/ kg body weight
per day for males
Detoksifikasi Metabolit 6.35 µg/kg body weight
pada suhu Fusarium per day for females
150 °C sp.
Metode yang digunakan menganilis
Fumonisin :
White-
hygroscopic 1. TLC
powder 2. HPLC
(larut air) 3. GC-MS
4. LC-MS
5. ELISA
Kesehatan
Manusia dan Hewan

Fumonisin

Perdagangan
Internasional Ekonomi
No Tahun Jumlah Sampel Konsentrasi % Kontaminasi Negara

1 1997 - 1999 25 formula bayi Ẋ = 44 ng/g; Maks: 130 ng/g 72% (18 dari 25 sampel) Canada
2 2004 - 2007 831 sampel Ẋ = 4.5 µg/kg; Maks: 8 µg/kg 3% - 35% Jepang
3 2002 - 2008 32 sampel 4% - 17% Fusarium sp Kroasia
36 Sampel
4 2008 -2010 Ẋ = 0.1 – 2.5 mg/kg 30.6% Italia
pakan
Amerika
5 2009 – 2011 60 sampel Ẋ = 230 ppb; Maks: 315 pp 5%
Selatan
Ẋ = 1017 ppb; Maks: 5088 Eropa
6 2009 – 2011 21 sampel 29%
ppb Selatan

7 2009 – 2011 35 sampel Ẋ = 316 ppb; Maks: 321 ppb 6% Asia Utara

Asia
8 2009 – 2011 109 sampel Ẋ = 265 ppb; Maks: 427 ppb 4%
Tenggara
138 – 1495 µg/kg FB1; 178 –
9 2015 39 sampel 10% Brasil Selatan
552 µg/kg FB2
14 – 440 0.006 – 7.1 0.03
µg/kg µg/kg µg/kg
BB/hari BB/hari BB/hari
Produk olahan jagung dalam bentuk tepung

• 2000 ppb atau µg/kg

Produk olahan jagung antara lain sereal sarapan


berbasis jagung, snack berbasis jagung
• 800 ppb atau µg/kg

Makanan pendamping air susu ibu (MP-ASI)


berbasis jagung
• 200 ppb atau µg/kg
Good Minimum
Agriculture + Toxicity Levels
Manufacture + Research
Practice Data

Government
Interventionsby
Regulations
Hibridisasi Fungisida Pengeringan
Bibit + +
Kedelai Biokontrol Dekontamin
Resisten asi 125-
Fusarium 150OC, 60
menit
- GC-MS Studi
Standardi
Assessment &
- LC-MS sasi Pengaturan
- ELISA Metode Rinci Mengenai
- HPLC dan Alur Fumonisin
(- BSLT) pada Produk
Analisis Pangan
Preparedness of Risk Other Step
Asessment

Toxicological
Data
Hazard Survey Method
identification Analytical Sampling
Data and
Analysis
REGULATION
Health Exposure Trade
Characterization essesment Sufficiency contact
food with other
supply country
Consumption
Risk Data
Characterization
Data Consumption of
Soybean
Trade of Soybeans
Trade of Soybeans
Sufficiency food supply