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 ⷪ᱗␿ᄽᶇἄ᱿ࡣ቏Ấ༬⧄㔄

‡෨᱿ᑨᐉ⭢ⳆΤʙ㆛᱿᳈〦Ễಙघञ ?
‡ᲿԊ᱿ᾷ᫧᮹෼՛: ᾷ᫧‫ۊ‬㆛ര᱿డᏈ⋍ᇓ?
‡෨᱿ᑨᐉ⣬⤟ᗉˑ㓯ᑂ᱿‫ۊ‬㆛?
‡ⳆΤ‫ۊ‬㆛ഛㅨӷ෨ᑨᐉ᱿Ễಙሷघᛖ?
‡ⳆΤᗞ⤟ᗉ᱿‫ۊ‬㆛ሳॖ̬ഛㅨӷ෨᱿ᑨᐉ‫ד‬ᾷ᫧Ꮘ᮹Ң˟ː?
‡෨᱿ᑨᐉଃ⤟ᗉ‫ۊ‬㆛ሷ̬ဏ⩀?
‡෨᱿ᑨᐉ⤺Ԭॖ̬૪⠗ⳆΤᲿᐻ?
‡ⳭໞᲿᐻ᱿Ἴ֯ӴᲩᣅ̬?
‡ⳭໞᲿᐻരሳଃᾷ᫧᮹Ң˟ːⳍໞ̬ỚӴᲩ?
 9

⋍ᇓ
ⷪ᱗ҝ‫ Ⲗ׮‬ᗼ⥑⤺ At a recent meeting, members discussed the
increasing incidence of a low success rate in heat shock protein 70
experiments. ⷪ᱗⤺Ԭ೘ᐉ Heat shock protein 70 can eliminate waste
material from damaged cells found in stroke patients. ⷪ᱗⤺Ԭ‫ۊ‬㆛
However, previous investigations induced mice to have heat shock
protein 70 by using a hyperthermia procedure, subsequently
decreasing the success rate of related experiments. (NOTE : Add 2-4
sentences that describe characteristics of the problem or statistics that
reflect its severity) డỄ⤺Ԭ‫ۊ‬㆛᱿⸇ջ For instance, the accuracy
rate of inducing heat shock protein 70 by using the hyperthermia
procedure does not exceed 20%, accounting for the low success rate of
related experiments. ⷪ᱗⤺Ԭ‫ۊ‬㆛᱿ʑൔ The inability to increase
the success rate of inducing mice to have heat shock protein 70 makes
it impossible to understand how stroke and this protein are related.
 9
⠗Ւ
ⷪ᱗⤺ԬᲿᐻ Therefore, we recommend developing a heat
shock protein 70 inducement procedure that contains a statistical
database of the mean atrial pressure and brain pressure for mice
responding to this protein, in which their heat shot responses can
be distinguished. ⷪ᱗Ჿᐻ᱿ᅞᘍ To do so, heat shot protein 70
can be inserted into the genetic sequence of mice. This protein
can then be observed by comfocal microscopy. Next, this protein
can be examined when the mice incur a heat stroke. శቃ᱿⃌ኞ
As anticipated, the proposed heat shock protein 70 inducement
procedure can verify that this protein prevents the degeneration of
mice cells by nearly 50%. The face that the mice carry this protein
can also be confirmed. ㅽࡍ᱿⪯᪇ Importantly, the proposed
procedure can facilitate an assessment of whether mice carry heat
shot protein 70, ultimately lowering the extent of harm to stroke
patients. (NOTE : Add 2-4 sentences that describe more
thoroughly how the proposed method contributes to a particular
field or sector)
 9 
⋍ᇓ
ⷪ ᱗ ҝ ‫ Ⲗ ׮‬ᗼ ⥑ ⤺ In our working group meeting last week, we
discussed our hospital¶s difficulty in enhancing the therapeutic outcome
of stroke patients. ⷪ᱗⤺Ԭ೘ᐉ With the increasing incidence of acute
ischemia strokes in recent year, computed tomography (CT) or
magnetic resonance imaging (MRI) is used to diagnose its early stages.
While diffusion weighted MRI is an effective means of detecting acute
strokes, water diffusion has been introduced as an additional MRI
contrast parameter. While demonstrating the feasibility of using
diffusion MRI to detect acute strokes in early stages, Mosely indicated
a significantly lowered diffusion coefficient in acute stroke areas. This
finding has become an important application of diffusion MRI since
conventional MRI has too low of a contrast for ischemic results,
especially in the very early and potentially reversible phase. As is well
known, among the available MRI approaches, diffusion weighted
imaging (DWI) is an important clinical procedure for diagnosing acute
cerebral infarctions.
 9 
⋍ᇓ
ⷪ᱗⤺Ԭ‫ۊ‬㆛ However, the conventional means of diagnosing acute cerebral
infarctions, in which clinical physicians review the medical history of patients
and current conditions as well as make a subjective assessment in diagnosing
stroke cases, normally makes it impossible not only to diagnose patients with
an acute stroke the first time, but also to identify the type and regional
geography of such a stroke accurately. (NOTE : Add 2 more sentences that
describe characteristics of the problem or statistics that reflect its severity) ⷪ
᱗⤺Ԭ‫ۊ‬㆛᱿⸇ջ For some stroke patients, conventionally used computed
tomography methods examine acute brain strokes, whose acute infraction area
has normally extended for over 24 hours. However, diffusion-weighted MRI
examines acute infraction stroke more effectively than CT does, i.e. up to 6
hours less time during examination of acute infract strokes. However, when
traditional DWI examination is performed to understand precisely the stroke
type and field range aspect, clinical physicians can only diagnose an acute
brain stroke from an image through visual observation. For instance, a small
infarct has a size of less than 3 mm. ⷪ᱗⤺Ԭ‫ۊ‬㆛᱿ʑൔ The inability to
diagnose an acute infract stroke accurately upon first examination makes it
impossible for clinical physicians to perform gold period grant medication
therapy for stroke patients. Consequently, the therapeutic outcome is poor, with
the extent of brain tissue damage not minimized to the lowest possible level,
possibly losing the opportunity for complete recovery of functions.
 9 ⠗Ւ
ⷪ᱗⤺ԬᲿᐻ Therefore, we recommend developing a quantitative
measurement method than can reconstruct and analyze a 3D infarct field
range. ⷪ᱗Ჿᐻ᱿ᅞᘍ To do so, patients with an acute infarction stroke
having occurred less than six hours previously can be examined by a
clinical physician. Diffusion-weighted MRI can then be performed to take
2D images. Next, 3D-Doctor software can be composed of a 3D image
by each slice of a 2D transverse image. Additionally, the interesting
infarct area can be identified and marked. Moreover, the level of severity
for infarct range can be marked by a darkish color of varying degrees. శ
ቃ᱿⃌ኞ As anticipated, the proposed method can identify an infarct
area with an order of severity by classifying grades according to a darkish
color of varying degrees. Moreover, the proposed method can also locate
an infarct area with an order of severity under 60% for purposes of
thrombus dissolution treatment. ㅽࡍ᱿⪯᪇ Importantly, the proposed
method can be used as a standard based on darkish colors of varying
degrees for clinical physicians attempting to determine the proper dosage
amount of medicine. (NOTE : Add 2-4 sentences that describe more
thoroughly how the proposed method contributes to a particular field or
sector)
Further details can be found at
http://www.chineseowl.idv.tw