Pain Issues
Issues and
and the
the Elderly
Elderly
*
Step II: Moderate Step III
Step II
Pain Step I
• Opioid medication
– With/without adjuvant analgesics
– Common medications:
• Hydrocodone, oxycodone, tramadol (Ultram)
• Duration= 3-4 hour, (except may have longer
relief with tramadol)
• Common combination drugs: Tylenol #3, Percocet,
Roxicet, Oxycet, Vicodin, Lortab, Lorcet, Fioricet.
Step III
Step II
Step III: Severe Step I
Pain
• Short acting opioids:
– For acute pain, rescue dosing, or titration of long acting
agents
– Common: Dilaudid, morphine sulfate IR, Roxanol, ACTIQ,
oxycodone
• Long acting:
– requires titration of short acting opioids
– Provides consistent 24 hr therapeutic blood levels
– 8-12 hrs: Oxycontin, MS Contin, Oramorph, methadone (long
t1/2 with shorter analgesic effect)
– 48-72 hrs duration: Duragesic
Opioids for Moderate to
Severe Pain
Long Acting
• Morphine (MS Contin, Oramorph SR,
Kadian
• Oxycodone (Oxycontin)
• Fentanyl (Duragesic)
• Methadone (Dolophine)
• Levorphanol (Levo-Dromoran)
Oxymorphone
Opioids for Moderate to
Severe Pain
Short Acting
• Morphine (Roxanol, MSIR)
• Oxycodone (Roxicodone, Oxy
IR)
• Fentanyl (Actiq)
• Hydromorphone (Dilaudid)
Oxymorphone
Management of Common
Opioid Side effects
• Constipation
- prophylactic use of laxatives and stool softeners
• Nausea and vomiting
- neuroleptics, metoclopramide, cisapride,
antivertigenous drugs
• Sedation
- discontinue other CNS depressants
- add psychostimulants
• Respiratory depression
- monitor if not severe; carefully titrate naloxone
if severe
Tolerance:
• pharmacological need to increase dose to
achieve the same effect over time in the
absence of advancing disease. Tolerance is
usually not problematic in chronic analgesic use.
Physical dependence:
• class-specific, predictable psycho-physiological
reaction to sudden cessation or blocking of a
drug. A tapering regimen will mitigate or stop
withdrawal.
Addiction
• overwhelming preoccupation with acquisition
• use of drug for non-medicinal purposes
• results in reduced quality of life and continued use
despite harm.
• Fewer than 0.1% of acute/chronic pain medication users
develop addiction behaviors (Jick, Portenoy).
Pseudo-addiction
• aberrant or illegal drug-seeking behavior similar to
addiction that is due to unrelieved pain, which stops
when adequate pain relief is achieved.
Neuropathic Pain-
Adjuvant Analgesics
• Tricyclic antidepressants
• Anticonvulsants
• Clonidine
• Corticosteroids
• Local anesthetics-Mexilitene
• Ketamine
• Baclofen
Nature of Pain
Neuropathic
Mechanism
Somatic,Visceral Psychosocial
Nociception Influences
Pain
Psychological Total
State and Traits Spirituality
Pain
Loss of Work Suffering Social / Family
Functioning
Physical
Financial Concerns Fear of Death
Disability
Emotional Pain “ hurts all over”
Most common palliative care symptoms
Anxiety; may present as sleeplessness,
reluctant to be left alone or overt fright
Anticipatory Anxiety; previous negative
experience becomes overwhelming
Treatment: relaxation & imagery,
acupressure, massage, music therapy,
hypnosis…. then maybe pharmacotherapy
such as lorazepam, haloperidol
Emotional Pain;
Care Giver Burden “ communication,
communication, communication”
Spirit of cooperation
Complex family dynamics emerge
Support to work through accumulated emotions
Can not take away all of the symptoms all the time
Imposing own expectations
Sense of presence is the very best medicine
Spirituality
The part of self where search for meaning
takes place.