GONZALES, LUZVIMINDA
L.
Types of Amines
• Alkyl Amines
CH3—NH2, CH3CH2—NH2,
• Aryl Amines
• Heterocyclic Amines
HETEROCYCLIC AMINES
Pyrole Guanine
Pyridine
6
• To name an amine, the suffix –amine is added to the
alkyl root name of the parent chain.
example: CH3—NH2 Methanamine
CH3CH2—NH2 Ethanamine
• The location of the amino group on the parent chain is
indicated by a number
example: NH2
│
CH3—CH2 — CH3 2-Propanamine
• Secondary and Tertiary Amines are commonly named as
N-substituted primary amines. The largest group
bonded to nitrogen is the parent chain.
example: CH3
│
CH3—NH N-methylmethanamine
EXERCISES:
PHYSICAL
PROPERTIES
A. Polarity
- amines are polar because of N
- able to form H-bond but less than alcohols
- able to form H-bond to themselves
- tertiary amines are not able to form H-bond
B. Boiling point
- have higher BP than comparable alkanes but
lower than alcohols
3 +Cl-
+ HCl
Norepinephrine Norepinephrine
chloride
EXERCISES:
1.CH3CH2NH2 + HCl
2.(CH3)2NH + HCl
3.(CH3)3N + HCl
4. + HCl
5. + HCl
APPLICATIONS
USES – MEDICINAL - ALKALOIDS
H
N
CH3
N
N
N
nicotine H H H
Yohimbine
H
CH3O
O OH
CH3O
CH2CH2NH C CH3
Hormone produced in the pineal
gland (center of the brain) -
N
An increase signals sleepiness
H for humans, large increase during
melatonin
schizophrenic episode, etc.