Normal
Age
Aggressive Periodontitis
Comprises a group of rare, often severe, rapidly progressive forms of periodontitis characterised by rapid rate of progression and a distinctive tendency for cases to aggregate in families Highly virulent flora or a high level of subject susceptibility to periodontal disease
Previous Classification
Prepubertal Periodontitis (PPP) Localised Juvenile Periodontitis Localised EarlyEarly-onset Periodontitis Generalised Juvenile Periodontitis & Rapidly Progressive Periodontitis Generalised Early-onset Periodontitis Early
Systemic diseases predisposing to Prepubertal periodontitis. Overlap between different disease entities. Too much dependance on age.
Except for the presence of periodontitis, patients are otherwise clinically healthy. Rapid attachment loss and bone destruction. Familial aggregation.
Amounts of microbial deposits are inconsistent with the severity of periodontal tissue destruction; Elevated proportions of Actinobacillus actinomycetemcomitans and, in some Far East populations, Porphyromonas gingivalis may be elevated; Phagocyte abnormalities; HyperHyper-responsive macrophage phenotype, including elevated levels of PGE2 and IL-1b in response to ILbacterial endotoxins; Progression of attachment loss and bone loss may be selfself-arresting.
Circumpubertal onset; Robust serum antibody response to infecting agents; Localized first molar/incisor presentation with interproximal attachment loss on at least two permanent teeth, one of which is a first molar, and involving no more than two teeth other than first molars and incisors.
Usually affecting persons under 30 years of age, but patients may be older; Poor serum antibody response to infecting agents; Pronounced episodic nature of the destruction of attachment and alveolar bone; Generalized interproximal attachment loss affecting at least three permanent teeth other than first molars and incisors.
Host Response
Defective chemotactic response in neutrophils HyperHyper-inflammatory state resulting in the presence of pro-inflammatory cytokines in the proserum. Phagocyte and macrophage abnormalities are minor in the sense that they are usually not associated with infections other than periodontitis.
Saxby (1987):West Midlands of England : (1987):West Overall prevalence of LJP was 0.1%. 6.8% incidence in Afro-Caribbean, 0.2% Asian, Afro0.02% Caucasian Saxen (1980):large-scale study of Finnish 16 year (1980):largeolds, prevalence to be 0.1%. Kronaeur et al. (1986), Prevalence of 0.1%. (1986), US school children by Loe and Brown (1991): 0.53% have LJP 0.13% had GJP; Blacks having the greatest amount of diseases, followed by Hispanics and finally Caucasians
Adjunctive antimicrobial therapy combined with scaling and root plaining with or without surgical therapy. Examples of antibiotics: Tetracyclins(avoid in children), metronidazole+ amoxycillin,azithromycin. -Evaluation and counseling of family members.
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