Female anatomy Male anatomy Female endocrinology Reproductive cycles Male endocrinology
Management systems for most animals are based upon the female reproductive cycle.
Estrus
Rebreeding
Weaning
Gestation Lactation
Birth
Management systems for most animals are based upon the female reproductive cycle.
Female Anatomy
Ovary Oviduct Uterus Cervix Vagina Vulva
Ovary
Contains thousands of growing follicles Each follicle contains an ovum or egg Receives a rich supply of both blood vessels and nerves
Ovary
Sow Ovary
Follicles
grow in response to hormones called gonadotropins either die (become atretic) or ovulate and release their egg.
Follicle Maturation
Ovulation
Follicle Maturation
Ovulation
Follicle Maturation Luteal Formation & Function
Ovulation
Follicle Maturation Luteal Formation & Function
Luteal Regression
Sow Ovary
CL Follicle
CA
CL Ovary
Oviduct
Funnel shaped organ Specialized end near ovary called the fimbria Fimbria picks up ovulated eggs
Oviduct (cont.)
Anterior end called ampulla Posterior end called isthmus Fertilization and early embryonic development takes place in the oviduct in most animals
Oviduct
Ovary
Oviduct
Uterus
Glandular inner lining surrounded by two layers of muscle Longitudinal and circular layers Responsible for maintenance of pregnancy Also releases the hormone that regresses luteal tissue
Uterus
Bladder
Uterus
Sow
Uterine horns
Cervix
Thick, muscular organ Serves to isolate the uterus from external environment during pregnancy
Vagina
part of the birth canal helps protect uterus from bacterial invasion site of semen deposition in most animals
Vulva
External female genitalia Outer portion of the vagina
Involved with recognition of receptivity and possibly with the production of female pheromones
Male Anatomy
Testicle Epididymis Vas deferens Secondary sex glands Penis (urethra) Sheath
Testicle
Series of tubules (seminiferous tubules)
Testicle
Series of tubules (seminiferous tubules) Produce spermatozoa Produce hormones (testosterone, androgens and others).
Epididymis (Epididymi)
continuation of tubule in testicle specialized for maturation and storage of spermatozoa immature sperm enter epididymis during their passage through epididymis they become mature
Vas deferens
Testicle
Epididymis
Vas deferens
Epididymis
Testicle
Testicle
Epididymis
Vas deferens
Muscular tube with a small diameter Passage for sperm from epididymis to urethra during ejaculation
Bulbourethral gland
Seminal Vesicles
Bladder
Seminal vesicles
Bladder
Bulbourethral gland
Seminal Vesicles
Bladder
Vas deferens
Penis
Male reproductive organ Specialized to deposit semen in female reproductive tract central canal is the urethra urethra is common exit for reproductive and urinary systems
Sheath
specialized pouch in which penis remains when not in use in some animals, the lining of the sheath is involved in male pheromone production.
Testicle
Epididymis
Urethra
Penis
Female Endocrinology
Three groups based on functions
gonadotropins - stimulate ovary sex steroids/prostaglandins - direct control of reproductive state mammotropins - involved with lactation
Gonadotropins
Luteinizing hormone (LH)
produced by the pituitary gland stimulates final growth of follicles causes ovulation also stimulates corpus luteum
Gonadotropins
Follicle stimulating hormone (FSH)
- produced by the pituitary gland - stimulates all stages of follicle growth, especially early periods
Sex Steroids/Prostaglandins
Progesterone
- produced by corpus luteum and the placenta (some animals) - responsible for maintenance of pregnancy - inhibits gonadotropin secretion
Sex Steroid/Prostaglandins
Estrogen (estradiol 17beta)
- produced by growing follicles, placenta and embryos - has both positive and negative effects on gonadotropins
Sex Steroids/Prostaglandins
Estrogen (cont.) - stimulates pre-ovulatory surge of gonadotropins - prepares female for breeding and parturition - responsible for female mating behaviors
Sex Steroids/Prostaglandins
Prostaglandin F2alpha
- primarily the uterus in the reproductive system - responsible for luteal regression - causes uterine contractions at birth
Mammotropins
Prolactin
- produced in the pituitary - stimulates production of milk
Mammotropins
Oxytocin
- produced by uterus and hypothalamus - stimulates milk excretion - stimulates uterine contractions
Estrus
Estrous cycles
Weaning
Gestation Lactation
Puberty
Birth
Reproductive cycles
involve interactions between the ovary, uterus mammary gland and brain these organs communicate with one another via hormones and nerves
Puberty
Puberty is generally defined as the age at which an animal is capable of adult reproductive function Females - estrus, production of fertile eggs and maintenance of pregnancy Males - libido, mating and production of fertile sperm
Puberty
In most animals, it is the brain and production of gonadotropins, specifically LH that is the last function to mature during puberty Ovaries and testes are capable of gamete and hormone production before puberty is reached
Estrous Cycle
repeatable sequence of events that results in female becoming sexually receptive
Estrous Cycle
Begins with estrus (period of sexual receptivity) at estrus, estrogen is high and progesterone is low high estrogen causes preovulatory surge of gonadotropins
Estrous Cycle
LH surge causes ovulation Follicles release eggs Estrogen decreases Corpora lutea (corpus luteum) form Progesterone is produced from CL
Estrous Cycles
Gonadotropin secretion is decreased because of progesterone Progesterone and CL are maintained for 12 to 16 days Prostaglandin is released from nonpregnant uterus Corpora lutea are destroyed
Estrous Cycles
Progesterone decreases LH and FSH increase Follicles grow Estrogen increases At certain level of estrogens, females exhibit estrus and then ovulate
Pregnancy
After ovulation, fertilization occurs and embryonic development occurs
1 cell
2 cell
4 cell
Pregnancy
In most females, their bodies do not realize that they are pregnant until around 12 days after fertilization
Pregnancy
At day 12 embryo sends a signal to mother prostaglandins are not released from the uterus progesterone is maintained Embryo begins to differentiate
Blastocyst
blastoceole
cells begin to differentiate and are unipotent (only develop into one type of tissue)
In the blastocyst,
inner cell mass become fetus proper cells within inner cell mass differentiate into bones, muscle, nerves, etc. trophoblast becomes placental membranes of fetus
Pregnancy
After embryo begins to differentiate and when it begins to take the shape and form of a young animal it is referred to as a fetus. Fetuses are still differentiating, but they also are increasing in size very rapidly.
80
Length (inches) 60
80
60 Weight (lbs)
40
20
40
20
0
0 1 2 3 4 5 6 7 Fetal Age of Calf (months) 8 9
Lactation
neural reflex arc
Neural Input
Endocrine Response
Lactation
neural reflex arc physical stimulation of nipple during nursing causes prolactin and oxytocin release prolactin - milk synthesis oxytocin - milk ejection
Rebreeding
Suckling action of young prevents release of LH and FSH (via another reflex arc) Once suckling is terminated by weaning or decreases in intensity, then LH and FSH increase and estrus results. The one exception is the mare.
Male Endocrinology
FSH and LH stimulate sperm production (spermatogenesis) FSH and LH stimulate testosterone production (mostly LH) process is fairly continuous, at least during the breeding season
Schematic of Reproduction
Ovary
Oviduct
Cervix
Vagina
Vulva
Ovary
Oviduct
Cervix
Vagina
Breeding
Vulva
Fertilization
Ovary
Oviduct
Embryonic & Fetal Growth
Cervix
Vagina
Parturition
Vulva