Cholinergic Drugs
Describe the cholinergic drug effects on major body systems. Discuss the nursing process related to the care of patients receiving cholinergic drugs for select problems.
Cholinergic Drugs
Drugs that stimulate the parasympathetic nervous system (PSNS)
opposing system to the SNS Known as: cholinergic agonists or parasympathomimetics Mimic the effects of the PSNS neurotransmitter:
acetylcholine (Ach)
Two types of Receptors:
Increased gastric secretions Increased gastrointestinal motility Increased urinary frequency Stimulate pupils Constriction (miosis) Reduced intraocular pressure Increased salivation and sweating
Cardiovascular effects
Decreased heart rate Vasodilation Respiratory effects Bronchial constriction, narrowed airways
them to empty Used to reverse postsurgical atony of the bladder and GI tract Oral dose or SC injection
Used to reverse neuromuscular blocking drugs/anesthesia Used to reverse anticholinergic poisoning (antidote)
Examples: physostigmine (Antilirium)
the medication
Overdosing can cause life-threatening problems. Only physicians
disease, be honest with caregivers and patients that the drugs are for management of symptoms, not a cure
Therapeutic effects of anti-Alzheimer s drugs may not
Increased bowel sounds Passage of flatus Occurrence of bowel movements In patients with urinary retention/hypotonic bladder, urination should occur within 60 minutes of bethanechol administration
ALSO monitor for adverse effects