DAFTAR ISI

HALAMAN JUDUL...i
LEMBAR PENGESAHANii
KATA PENGANTARiii
DAFTAR ISI...iv
DAFTAR GAMBAR..vi
DAFTAR TABEL..vii
DAFTAR BAGANvii
BAB I. PENDAHULUAN
I.1. Latar Belakang...................................................................................................1
BAB II. TINJAUAN PUSTAKA
II.1. Definisi.............................................................................................................2
II.2. Epidemiologi....................................................................................................3
II.3. Etiologi.............................................................................................................4
II.4. Patogenesis.......................................................................................................5
II.5. Diagnosis
II.5.1. Manifestasi Sistemik...........................................................................10
II.5.2. Manifestasi Spesifik Paru....................................................................11
II.6. Pemeriksaan Penunjang
II.6.1. Uji Tuberkulin.....................................................................................12
II.6.2. Uji Interferon......................................................................................13
II.6.3. Radiologi.............................................................................................14
II.6.4. Serologi...............................................................................................14
II.6.5. Mikrobiologi........................................................................................14
II.6.6. Patologi Klinik....................................................................................14
II.7. Penatalaksanaan
II.7.1. Obat TB Yang Digunakan.................................................................17
II.7.2. Panduan Obat TB...............................................................................21
II.7.3. Evaluasi Hasil Pengobatan.................................................................22
II.7.4. Evaluasi Efek Samping Pengobatan...................................................23
II.7.5. Putus Obat..........................................................................................24

iv

II.7.6. Multi Drug Resistance (MDR) TB.24

II.8. Non Medikamentosa
II.8.1. Pendekatan DOTS (Directly Observed Treatment Shortcourse..25
II.8.2. Sumber penularan dan case finding25
II.8.3. Aspek edukasi dan sosial ekonomi.26
II.9. Pencegahan
II.9.1. Imunisasi BCG..26
II.9.2. Kemoprofilaksis.27
II.10. Komplikasi dan Prognosis
II.10.1.Komplikasi..28
II.10.2. Prognosis28

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DAFTAR GAMBAR

Gambar 1. Bakteri Mikobakterium tuberkulosa..4

Gambar 2. Patogenesis Tuberkulosis.......................................................................8
Gambar 3. Kalender Perjalanan Penyakit TB Primer..............................................9
Gambar 4. Gambar 4. Hasil uji tuberculin.13

vii

DAFTAR TABEL

Tabel 1. Skoring TB Anak.....................................................................................15

viii

DAFTAR BAGAN

Bagan 1. Skrining Tuberkulosis.............................................................................17