K2 - K3 Fis Intra-Ekstra Uterine
K2 - K3 Fis Intra-Ekstra Uterine
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PROSES KELAHIRAN
(Perubahan Link. Intrauterine Link. Ekstrauterine)
KONTRAKSI uterus
at term
(Frekuensi-Durasi-Intensitas)
Bayi Menangis
Tahanan paru
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Bbrp. Jam postpartum
1 - 4 Bulan
Fibrosis Occluded
Sirkulasi Dewasa
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Circulation in Fetus and Newborn
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PERUBAHAN SIRKULASI
PLASENTA PLASENTA
FO
FO
PARU PARU
PARU PARU
DA DA DA
FO : Foramen Ovale
DA : Ductus Arteriosus 9
MENARIK NAFAS PERTAMA (The First Breath)
Bayi Lahir
Pusat Pernapasan
STRESS
Regulasi Suhu
BELUM STABIL
Suhu Tubuh
TDK STABIL
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Regulasi Suhu Blm. Stabil
BB (5-10%) 2-3 Hr
pertama
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FUNGSI LIVER
GLIKOGEN
LIVER, OTOT, JANTUNG,
dll
Beberapa jam
postpartum GLIKOGEN
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REGULASI GLUKOSA
Bbrp. jam
Glikogen
GLUKONEOGENESIS
Gangguan/gagal
KGD <20mg/100mL
Pemberian
Glukosa
Ggn. Syaraf & Koma
Apnoe + Cyanosis
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METABOLISME PROTEIN & LEMAK
Fetus
Sintesa di Hati :
Albumin & Lemak
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BILIRUBIN & FUNGSI DETOXIFIKASI
Blm. Sempurna
Physiological
Joundice (3-7 Hari)
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TRACT. GASTROINTESTINALIS
PERTUMBUHAN
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Thyroid Gland
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Adrenal Korteks
Pada urine Kortikosteroid (+)
Saat Lahir
PO2
ASPHYXIA
Adrenal Epinephrin/NE
Medula
VASOKONSTRIKSI
Sifat Refleks
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PERAN HORMON DALAM
PROSES TUMBUH DAN
KEMBANG
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Multiple hormones, including growth hormone (GH),
insulin-like growth factors (IGF-I and -II), insulin, thyroid
hormones, glucocorticoids, androgens, and estrogens
contribute to the growth process in humans.
Among these, GH and IGF-I have been implicated as the
major determinants of growth in normal postuterine life.
However, deficiencies (or excesses) of each of the other
hormones can seriously affect the normal growth of the
musculoskeletal system as well as the growth and
maturation of other tissues.
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Pancreas: Insulin
actions: hypoglycemic (lowers blood
glucose)
increases transport of glucose into muscle and fat
cells (NOTE: does not increase uptake by brain,
liver, or kidney)
inhibits breakdown of glycogen and formation of
glucose from amino acids or fatty acids (inhibits
glycogenolysis and gluconeogenesis)
promotes formation of glycogen (liver, skeletal
muscles), protein synthesis (muscle), and fat
synthesis and storage (adipose)
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5. Pancreas: Insulin (Control)
stimulated by:
increased blood glucose
increased blood amino acid
and fatty acid levels
parasympathetic impulses
hyperglycemic hormones
(GH, glucagon, epinephrine,
thyroxine, glucocorticoids)
indirectly result in insulin
secretion by increasing blood
glucose levels
inhibited by:
low blood glucose and by
somatostatin
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sympathetic impulses
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