Asam amino

Asam karboksilat yang mengandung gugus amino

Ada lebih dari 100 macam asam amino di alam
Hanya 20 macam asam amino yang menyusun
protein
Seluruh protein alami hanya tersusun dari 20 jenis
asam amino penyusun protein tersebut.
 Struktur umum Asam amino

NH2 COO
H
CH

R1 O

NH3 C O-
+
CH

R1
 20 asam amino penyusun protein

Alanin Arginin Aspartat

Asparagin Fenilalanin Glisin
Glutamat Glutamin Histidin
Isoleusin Leusin Lisin
Metionin Prolin Tirosin
Treonin Triptofan Serin
Sistein Valin
 Klasifikasi Asam amino penyusun
protein
1. Non polar hydrophobic Amino Acids (Rantai
samping bersifat non polar hidrofobik)

2. Hydrophilic polar Amino Acids (Rantai samping

bersifat polar, hidrofilik)

3. Acidic Hydrophilic Amino Acids (Rantai samping

bersifat asam, hidrofilik)

4. Basic Hydrophilic Amino Acids (Rantai

samping bersifat basa, hidrofilik)
Non polar hydrophobic Amino Acids
Hydrophilic polar Amino Acids
 Acidic & Basic Hydrophilic Amino Acids

Aspartic Acid Asp D

Hydrophilic
Acidic
Glutamic Acid Glu E

Lysine Lys K

Hydrophilic Arginine Arg R

Basic

Histidine His H
 R2 Pembentukan peptida

NH2 COO CH
H
CH NH2 COO
H
R2
R1
NH2 CH
CO
CH NH COO
H

R1
Ikatan peptida
Pentapeptida

Ikatan peptida