ZULIDA SURYAFITRI (12100112046) FAKULTAS KEDOKTERAN UNISBA Preceptor : Dyana Eka H, dr., Sp.

Rad

SMF RADIOLOGI RSUD AL-IHSAN BANDUNG

= Osteogenik Sarkoma
Suatu tumor ganas primer tulang yg pembentukannya berasal dr seri osteoblas sel mesenkim primitif pembentuk tulang & ditandai oleh adanya produksi osteoid. Paling sering terjadi pada bagian metafisis dari tulang panjang anak-anak.

 Di

USA, insidensi pd usia < 20 thn 4,8 kasus/1 juta populasi pd orang Amerika Afrika >>

Insidensi

Kaukasia
Lebih

sering terjadi pd laki2 dibandingkan wanita (3:2)

UNKNOWN DISEASE

1. 2.

3.

Pertumbuhan tulang yg cepat Faktor lingkungan Predisposisi genetik

 Femur

(42%) dgn 75% tumor di tulang femur distal Tibia (19%) dgn 80% tumor di tibia proksimal Humerus (10%) dgn 90% tumor di humerus proksimal Tengkorak/rahang (8%) Panggul (8%).

1.

2. 3.

4.

Nyeri, dan/atau pembengkakan ekstremitas yg terkena Fraktur patologik Pembengkakan pd/diatas tulang/persendingan Pergerakan yg terbatas

5. 6. 7. 8.

Teraba massa tulang Peningkatan suhu kulit diatas massa Adanya pelebaran vena Gejala2 penyakit metastatik (nyeri dada, batuk, demam, BB turun, malaise)

The tumor is densely sclerotic, but an area of lucency and cortical destruction is shown proximally on its lateral margin. Scalloping of the cortex is observed inferior to this area, with amorphous mineralized osteoid shown in the soft tissues (arrow).

Lateral radiograph of the calcaneum in an adult with osteosarcoma shows a predominantly lucent lesion in the anteroinferior part of the bone and cortical destruction.

Radiograph of the femur in a patient with osteosarcoma shows a typical Codman triangle (arrow) and more diffuse, mineralized osteoid within the soft tissues adjacent to the bone.

Lateral radiograph of the distal femur in a child with osteosarcoma involving the metaphysis and metadiaphysis. Note the abnormal texture and mild sclerosis of the distal femoral shaft; the aggressive periosteal changes, including Codman triangles (white arrow); and the large soft tissue mass (black arrow).

Reaksi periosteal ketika tumor telah menembus kortek, sunburst appearance

Fraktur Patologis

TERIMAKASIH