DAFTAR ISI

Halaman
ABSTRACT ..................................................................................................... v
ABSTRAK ...................................................................................................... vi
KATA PENGANTAR ..................................................................................... vii
DAFTAR ISI ................................................................................................... ix
DAFTAR TABEL ........................................................................................... xi
DAFTAR GAMBAR ...................................................................................... xii
DAFTAR LAMPIRAN ................................................................................... xiii
BAB I

PENDAHULUAN .........................................................................
1.1 Latar Belakang ........................................................................
1.2 Perumusan Masalah .................................................................
1.3 Tujuan Penelitian .....................................................................
1.4 Manfaat Penelitian....................................................................

1
1
4
5
5

BAB II

TINJAUAN PUSTAKA ................................................................

2.1 Rumah Sakit ............................................................................
2.2 Pelayanan Farmasi Rumah Sakit .............................................
2.3 Standar Pelayanan Minimal Rumah Sakit ...............................
2.4 Mutu Pelayanan Kesehatan .....................................................
2.5 Kepuasan Pelanggan ...............................................................
2.6 Profil RSUD Sawahlunto ........................................................
2.7 Kerangka Teori ........................................................................
2.8 Kerangka Konsep .....................................................................

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7
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19
20

BAB III. METODE PENELITIAN ..............................................................

3.1 Desain Penelitian .....................................................................
3.2 Lokasi dan Waktu Penelitian ...................................................
3.3 Populasi dan Sampel ................................................................
3.4 Besar Sampel dan Teknik Pengambilan Sampel .....................
3.5 Variabel Penelitian ..................................................................
3.6 Definisi Operasional ................................................................
3.7 Pengolahan dan Analisis Data .................................................
3.8 Etika Penelitian .......................................................................

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27
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BAB IV

28
38
39
33

BAB V

HASIL PENELITIAN ...................................................................

4.1 Data Hasil Penelitian ...............................................................
4.2 Analisis Data Hasil Penelitian .................................................
PEMBAHASAN ...........................................................................
x

5.1 Pengaruh Diabetes Terhadap Indeks Aterogenik plasma ........ 45

5.2 Pengaruh Kombinasi Glibenklamid dan Minyak Buah Merah
Terhadap Indeks Aterogeik ..................................................... 47
BAB VI

SIMPULAN DAN SARAN .......................................................... 38

6.1 Simpulan .................................................................................. 38
6.2 Saran ........................................................................................ 39

DAFTAR PUSTAKA ..................................................................................... 40

LAMPIRAN .................................................................................................... 42
DAFTAR RIWAYAT HIDUP ........................................................................ 43

xi

DAFTAR TABEL

Tabel 2.1 Komposisi kimia 100 gram minyak buah merah....................................

9
Tabel 2.2 Kriteria diagnosis DM ...........................................................................
11
Tabel 3.1 Penentuan jumlah sampel minimal ........................................................
27
Tabel 4.1 Nilai rata-rata SD (standar deviasi) kadar trigliserida, HDL, dan
indeks aterogenik plasma tikus jantan galur Wistar terhadap berbagai
perlakuan (mg/dl) ...................................................................................
38
Tabel 4.2 Nilai signifikansi trigliserida, HDL, dan indeks aterogenik dengan uji
ANOVA .................................................................................................
39
Tabel 4.3 Perbandingan berbagai perlakuan terhadap kadar trigliserida plasma
tikus dengan post hoc (p<0,05) ............................................................
40
Tabel 4.4 Perbandingan berbagai perlakuan terhadap HDL plasma tikus dengan
post hoc (p<0,05) ..................................................................................
41
Tabel 4.5 Perbandingan berbagai perlakuan terhadap indeks aterogenik plasma
tikus dengan post hoc (p<0,05) ............................................................
43

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DAFTAR GAMBAR

Gambar 2.1 Daun tanaman buah merah .................................................................

7
Gambar 2.2 Akar tanaman buah merah ..................................................................
7
Gambar 2.3 Buah merah .........................................................................................
8
Gambar 2.4 Mekanisme kerja sulfonilurea dalam mensekresikan insulin .............
13
Gambar 2.5 Patogenesis aterosklerosis ..................................................................
16
Gambar 2.6 Sintesis trigliserida .............................................................................
17
Gambar 2.7 Sekresi dan maturasi HDL .................................................................
19
Gambar 2.8 Sumber dan respon seluler terhadap ROS ..........................................
21

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Gambar 2.9 Kerangka teori penelitian ...................................................................

23
Gambar 2.10 Kerangka konsep penelitian ...............................................................
24
Gambar 3.1 Pengelompokkan hewan coba ...........................................................
32
Gambar 3.2 Skema alur penelitian .........................................................................
34

DAFTAR LAMPIRAN

Statistik .....................................................................................................................
59
Etik ...........................................................................................................................
71
Curiculum vitae ........................................................................................................
72

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