DAFTAR ISI

Halaman
KATA PENGANTAR ..................................................................................... i
DAFTAR ISI.................................................................................................... ii
DAFTAR LAMPIRAN...................................................................................iii
DAFTAR GAMBAR....................................................................................... v
PENDAHULUAN .......................................................................................... 1
BAB
I

TINJAUAN PUSTAKA 3
1.1 Tinjauan Botani........................................................................... 3
1.2 Kandungan Kimia........................................................................7
1.3 Efek Farmakologi........................................................................9
1.4 Ekstraksi......................................................................................10
1.5 Karakteristik................................................................................11
1.6 Tinjauan Antihiperurisemia ........................................................13
1.7 Metode Uji Aktivitas Penghambatan Xantin Oksidase...............23

II

METODOLOGI PENELITIAN ........................................................26

III

ALAT DAN BAHAN...........................................................................27

3.1 Alat..............................................................................................27
3.2 Bahan...........................................................................................28

IV

RENCANA KERJA ............................................................................30

4.1 Penyiapan bahan..........................................................................30

4.2 Karakteristik Simplisia................................................................31

4.3 Penapisan Fitokimia....................................................................35
4.4 Ekstraksi......................................................................................37
4.5 KLT (kromatografi lapis tipis).....................................................38
4.6 Penetapan Kadar Flavonoid Total................................................38
4.7 Penetapan Kadar Fenol Total.......................................................38
4.8 Perhitungan Dosis dan Pembuatan sediaan.................................39
4.9 Pengujian Aktivitas PenghamabatanXantin Oksidase.................39
DAFTAR PUSTAKA......................................................................................42
LAMPIRAN ...................................................................................................44

DAFTAR LAMPIRAN

Lampiran

Halaman

1. DAUN SALAM...............................................................................44
2. BAGAN PROSES EKSTRAKSI.....................................................45
3. PENGUJIAN AKTIVITAS PENGHAMABATAN
XANTIN OKSIDASE .....................................................................46

DAFTAR GAMBAR
Gambar
Halaman
1.1 Mekanisme Pembentukkan Asam Urat......................................................13
1.2 Lokasi Kerja Obat Alopurinol....................................................................23
1.3 Daun Salam ..............................................................................................44
1.4 Bagan Proses Ekstraksi .............................................................................45
1.5 Bagan Pengujian Aktivitas Penghambatan Xantin Oksidase......................46