DAFTAR ISI

HALAMAN
LEMBAR PENGESAHAN .......................................................................... i
DAFTAR ISI ................................................................................................ ii
DAFTAR SINGKATAN ................................................................................ iv
DAFTAR ISTILAH ....................................................................................... vi
DAFTAR GAMBAR ..................................................................................... vii
DAFTAR LAMPIRAN .................................................................................. viii
BAB I PENDAHULUAN .............................................................................. 1
I.1 Latar Belakang ............................................................................ 2
I.2 Rumusan Masalah ....................................................................... 9
I.3 Tujuan Penelitian ......................................................................... 9
I.3.1 Tujuan Umum ..................................................................... 9
I.3.2 Tujuan Khusus ................................................................... 9
I.4 Hipotesis ......................................................................................10
I.5 Manfaat Penelitian .......................................................................11
BAB II TINJAUAN PUSTAKA ....................................................................12
II.1 Stroke .........................................................................................12
II.1.1 Definisi Stroke ...................................................................12
II.1.2 Epidemioligi Stroke ...........................................................12
II.1.3 Klasifikasi Stroke ...............................................................15
II.1.4 Faktor Resiko ....................................................................19
II.1.5 Patofisiologi Stroke ........................................................... 20
II.1.6 Manajemen Umum Stroke ................................................ 26
II.1.7 Outcome Stroke ................................................................ 27
II.2 Albumin ....................................................................................... 29
II.2.1 Fisiologi Albumin ............................................................... 29
II.2.2 Metabolisme dan Sintesa Albumin .................................... 35
II.2.3 Peranan Albumin Pada Stroke Akut .................................. 35
II.3 Osmolaritas Plasma ................................................................... 38
II.3.1 Hubungan Outcome Stroke dengan Osmolaritas Plasma. 45
II.4 Kerangka Teori ........................................................................... 49
II.5 Kerangka Konsep ....................................................................... 50
BAB III METODE PENELITIAN .................................................................. 50
III.1 Tempat dan Waktu ..................................................................... 50
III.2 Subjek Penelitian ....................................................................... 50
III.2.1 Populasi Sasaran ............................................................. 50
III.2.2 Populasi Terjangkau ......................................................... 50
III.2.3 Besar Sampel ................................................................... 51
III.2.4 Kriteria Inklusi ................................................................... 51
III.2.5 Kriteria Eksklusi ............................................................... 51
III.3 Batasan Operasional ................................................................. 52

III.4 Rancangan Penelitian ............................................................... 53

III.5 Pelaksanaan Penelitian ............................................................. 54
III.5.1 Instrumen ......................................................................... 54
III.5.2 Pengambilan Sampel ....................................................... 54
III.5.3 Kerangka Operasional ..................................................... 55
III.5.4 Variabel yang Diamati ...................................................... 56
III.5.5 Analisa Statistik ................................................................ 56
III.5.6 Jadwal Penelitian ............................................................. 56
III.5.7 Biaya Penelitian ............................................................... 57
III.5.8 Personalia Penelitian ....................................................... 57
DAFTAR PUSTAKA .................................................................................... 58