DAFTAR ISI

HALAMAN JUDUL .............................................................................................i

HALAMAN PERSETUJUAN UJIAN PROPOSAL .........................................ii

DAFTAR ISI ..........................................................................................................iii

DAFTAR TABEL ..................................................................................................vi

DAFTAR GAMBAR .............................................................................................vii

BAB I AWAL ..........................................................................................................1

1.1 Latar Belakang .................................................................................................1

1.2 Rumusan Masalah ............................................................................................4

1.3 Tujuan Penelitian ..............................................................................................5

1.3.1 Tujuan Umum ...........................................................................................5

1.3.2 Tujuan Khusus ..........................................................................................5

1.4 Manfaat Penelitian ...........................................................................................6

1.4.1 Manfaat Penelitian ....................................................................................6

1.4.2 Manfaat Teoritis ........................................................................................6

1.4.3 Manfaaat Praktis .......................................................................................6

1.4.4 Manfaat Institusi .......................................................................................7

BAB II TINJAUAN PUSTAKAN ....................................................................... 8

2.1 Karies ..............................................................................................................8

2.1.1 Epidemiologi karies .....................................................................................8

2.1.2 Definisi karies ..............................................................................................8

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2.2 Daun Sirih Merah (Piper crocatum) ................................................................9

2.2.1 Morfologi Sirih Merah.................................................................................9

2.2.2 Kandungan daun sirih merah .........................................................................10

2.2.3 Manfaat daun sirih merah...........................................................................10

2.3 Sirih hijau (Piper betle L.) ..............................................................................11

2.3.1 Morfologi sirih hijau .................................................................................11

2.3.2 Kandungan sirih hijau ...............................................................................12

2.3.1 Manfaat daun siri hijau ..............................................................................14

2.4 Streptococcus mutans .....................................................................................14

2.4.1 Definisi dan morfologi Streptococcus mutans ..........................................14

2.4.2 Peran Streptococcus mutans dalam pembentukan karies ..........................15

2.5 Anti bakteri.....................................................................................................16

BAB III KERANGKA PENELITIAN ...............................................................17

3.1 Kerangka Teori ...............................................................................................17

3.2 Kerangka Konsep ...........................................................................................18

BAB IV METODE PENELITIAN .....................................................................19

4.1 Jenis Penelitian ...............................................................................................19

4.2 Desain Penelitian.............................................................................................19
4.3 Variabel Penelitian .........................................................................................19
4.4 Tempat dan Waktu Pelaksanaan Penelitian ....................................................19
4.5 Metode Penelitian...........................................................................................20
4.6 Sampel Penelitian............................................................................................20
4.7 Estimasi Pengulangan Sampel .......................................................................20
4.8 Alat dan Bahan Penelitian ..............................................................................21 iv
4.8.1 Alat.............................................................................................................21
 4.8.2 Morfologi Sirih Merah..............................................................................22

4.9 Kriteria Sampel ............................................................................................. 22

4.10 Definisi Operasional dan Kriteria Objektif ...................................................23

4.11 Istrumen Pengambilan Data .........................................................................26

4.12 Analisa Data...................................................................................................27

4.13 Prosedur Penelitian ...................................................................................... 27

4.13.1 Sterilisasi Alat..........................................................................................27

4.13.2 Pembuatan Medium.................................................................................28

4.13.3 Pembuatan Ekstrak Daun Sirih Merah ( Piper Crocatum) dan Daun Sirih

Hijau (Piper Betle Linn)..........................................................................29

4.13.4 Pengenceran Ekstrak Daun Sirih Merah ( Piper Crocatum)....................30

4.13.5 PengenceranEkstrak Daun Sirih Hijau (Piper betle L.) ..........................31

4.13.6 Uji Daya Hambat......................................................................................32

4.14 Alur Penelitian .............................................................................................34

4.14.1 Pengenceran Ekstrak Daun Sirih Merah..................................................35

4.14.1 Pengenceran Ekstrak Daun Sirih Hijau....................................................35

DAFTAR PUSTAKA

DAFTAR GAMBAR v

Gambar 2.1. Daun Sirih Merah ....................................................................... 10

Gambar 2.2. Daun Sirih Hijau ......................................................................... 12

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