Fertilization Embryological
(Conception) Development (0 - 2 months)
Prenatal
Development
Polar bodies
4-cell stage
2-cell stage Early morula
DAY 1 DAY 2
DAY 3 Advanced
DAY 4 morula
First cleavage Shedding
division of zona
Inner pellucida
DAY 0: cell mass
Fertilization
DAY 6
Blastocoele
Ovulation
Stages of
Differentiati Myeloid stem cell Lymphoid stem cell
on of Blood
Cells Proerythroblast Myeloblasts Monoblast Megakaryoblast
Promyelocytes Promonocyte
Early erythroblast
Promegakaryocyte
Late erythroblast
Neutrophilic
band cell
Granular leukocytes
Erythrocyte
THE CELL THEORY
1. All living things are made of cells.
(basic structure).
2. All cells carry out life functions.
(basic function)
3. All cells come from pre-existing
cells.
Levels of organization
Cell- basic unit of life.
Tissue- group of cells performing the same
function. Lung tissue
Organs- group of tissues performing the
same function. Lung, heart
Organ system- group of organs that
perform the same function.ex. Respiratory
system
Organism- group of organ systems working
together.
Parts of a Cell
Ribosome- synthesis proteins
Nucleus- controls cell activity
Cell membrane- regulates what
enters and leaves the cell
Mitochondria- carries out cellular
respiration to release energy.
Endoplasmic reticulum- system of
channels that transport materials.
Smooth ER- without ribosome
Rough ER- with embedded
ribosome.
Lysosomes- digestive enzymes to
break down substances.
Nucleolus synthesize ribosome.
Cytoplasm- liquid portion of the
cell
Vacuoles storage bins of the cell.
Largest cell in the world
The
egg
from
an
ostric
h
15cm
How many cells are in the
Human Body
Approximatel
y 65 trillion
cells make
up the adult
human body
Stem cells
Properties of stem cells.
Embryonic stem cells (ESC) from inner mass cells, totipotent
can give rise to all embryonic cells except trophoblast
ectoderm, endoderm and mesoderm.
ESC form pluripotent stem cell committed stem cell then
progenitor/precursor cells differentiate into a cell lineage.
Adult stem cells more lineage-restricted in their ability to
differentiate
Restriction on the potency of stem cells is determined by
the microenvironment
Stem cells
Adult stem cells important for the continual production of
tissues e.g intestinal epithelium.
Expression of transcription factor e.g Oct-4 is required for
the maintenance of pluripotency.
Murine embryonic stem cells useful models to elucidate
the unique properties of mammalian stem cells.
Valuable therapeutic potential in treatment of
degenerative diseases.