9

NAMA KELOMPOK 9:
PAULA RAMONA
REHAN SASLI RAMADHAN
RISKA ANIS MAHDIYYAH
WARDATI RAUDAH
WINA HELPI AIDIL
WULAN OCTAVIA P.MUCHANI
ZURA ASHARA
 01
SEDIAAN GUTTAE

Obat tetes (guttae) merupakan sediaan cair berupa

larutan, emulsi atau suspensi, dimaksudkan untuk
obat dalam atau obat luar. Digunakan dengan cara
meneteskan menggunakan penetes yang
menghasilkan tetesan setara dengan tetesan yang
dihasilkan penetes baku yang disebutkan
farmakope Indonesia.
 Formula Umum Guttae

● Zat aktif
● Bahan tambahan:
 Pengental
 Pensuspensi (untuk bentuk sediaan
suspensi)
 Pengawet
 Antioksidan dll
● Pelarut/cairan pembawa
Sediaan obat tetes dapat berupa antara lain:

● Guttae (obat dalam)

● Guttae Oris (tetes mulut)
● Guttae Auriculares (tetes telinga)
● Guttae Nasals (tetes hidung)
● Guttae Opthalmicae (tetes mata)
 Guttae Oris
Guttae Oris (tetes mulut) adalah obat yang
digunakan untuk mulut dengan cara
mengencerkan lebih dahulu dengan air untuk
dikumur-kumurkan, tidak untuk ditelan.

Contoh obat
Guttae Oris
 Komponen Penyusun

R/ Parasetamol 0,1 Zat Aktif

Propilenglikol ad 11 ml Pengawet

m.F gutt oris 15 ml

s.t.d.d gtt 10

Pro Tn Ditto

Note:
Adapun zat pelarut pada pembuatan tetes mulut ini yaitu Aquadest,
hanya saja pada resep yang didapat tidak tercantum pelarutnya.
 Metode Pembuatan Guttae Oris Parasetamol

Botol dikalibrasi. Parasetamol 0,1 gr dilarutkan dalam

01 Propilenglikol ad 11 ml

Diberi
etiket
02 Dipindahkan kemortir dan diaduk hingga larut putih dan
dilakukan
evaluasi
sediaan

03 Dimasukkan kedalam botol + Aquadest ad 15 ml

Evaluasi Guttae Oris Pct
• Bentuk = Larutan
• Rasa = Pahit
Uji Organoleptis • Warna = Putih keruh
• Bau = Tidak berbau
• Kejernihan = Keruh

• Massa Air= 5,2 gr

• Massa Sediaan= 5,7 gr
Uji Bobot Jenis • Massa Jenis Air= 1,04 gr/ml
• Massa Jenis Sediaan= 1,14
gr/ml
• Bobot Jenis= 1,1
Uji
PH
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Venus has a beautiful name and is the
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MY EXPERIENCE
2002 COMPANY 2 2016 COMPANY 4
Despite being red, Mars Pluto is now a dwarf
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Venus has a beautiful Saturn is a gas giant and
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PROMOTION
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Despite being red,
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PRESENTATIO
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ART
FESTIVALS
Pluto is a dwarf
planet
MY SERVICES
MERCURY VENUS MARS
It’s the closest planet to It’s the second planet Despite being red,
the Sun from the Sun Mars is a cold place

JUPITER SATURN NEPTUNE

It’s the biggest planet of Saturn is a gas giant and It’s the farthest planet
them all has rings from the Sun
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