DAFTAR ISI

SAMPUL DALAM ................................................................................................................... i

PRASYARAT GELAR ............................................................................................................ iii
LEMBAR PERSETUJUAN. ......................................................................................... ......... iv
PENETAPAN PANITIA PENGUJI ....................................................................................... v
UCAPAN TERIMAKASIH .....................................................................................................vi
DAFTAR ISI ........................................................................................................................... vii
DAFTAR TABEL .................................................................................................................. viii
DAFTAR SINGKATAN ............................................ ix
BAB I PENDAHULUAN ....................................................................................................... 1
1.1 Latar Belakang .................................................................................................................. 1
1.2 Rumusan Masalah ............................................................................................................. 3
1.3 Tujuan Penelitian .............................................................................................................. 3
1.4 Manfaat Penelitian ............................................................................................................ 3
BAB II KAJIAN PUSTAKA ................................................................................................. 4
2.1 Definisi .............................................................................................................................. 4
2.2 Etiologi .............................................................................................................................. 5
2.3 Patogenesis ........................................................................................................................ 5
2.4 Fase LMK ......................................................................................................................... 6
2.4.1 Fase Kronik .................................................................................................................. 6
2.4.2 Fase Akselerasi ............................................................................................................. 7
2.4.3 Blast Crisis ................................................................................................................... 7
2.5 Manifestasi Klinis ............................................................................................................. 8
2.6 Diagnosis ........................................................................................................................... 8
2.7 Diagnosis Banding............................................................................................................ 10
2.8 Penatalaksanaan................................................................................................................ 11
2.9 Prognosis............................................................................................................... 15
BAB III KERANGKA BERPIKIR DAN KONSEP PENELITIAN.....16
3.1 Kerangka Berpikir......................................................................................................16
3.2 Konsep Penelitian......................................................................................... 17
BAB IV METODE PENELITIAN ............................................................................... 18
4.1 Rancangan Penelitian.................................................................................................18
4.2 Lokasi dan Waktu Penelitian.............................................................................................18
4.3 Subjek dan Sampel 18
4.3.1 Variabilitas Populasi.....................................................................................................18
4.3.2 Kriteria Subjek..................................................................................................19
4.3.3 Teknik Penentuan Sampel.............................................................................................19
4.4 Variabel......................................................................................................20
4.4.1 Identifikasi Variabel .....................................................................................................20
4.4.2 Definisi Operasional Variabel.......................................................................................20
4.4.3 Bahan dan Instrumen Penelitian ...................................................................................21
4.5 Protokol Penelitian.....................................................................................................22

4.6 Analisis Data......................................................................................................22

4.7 Kelemahan Penelitian........................................................................................................22
DAFTAR PUSTAKA ............................................................................................................. 45
LAMPIRAN ........................................................................................................................... 50