Aripripazol

Fluoxetine
The efficacy of selective serotonin reuptake inhibitors (SSRIs) is superior to placebo
and comparable to other classes of antidepressants in treating patients with major
depression.2,32 SSRIs are generally chosen as first-line antidepressants because
of their safety in overdose and improved tolerability.
The selective serotonin reuptake inhibitors (SSRIs) inhibit the reuptake of 5-HT into
the presynaptic neuron. They are generally chosen as firstline antidepressants
because of their safety in overdose and improved tolerability compared to earlier
agents.
Cipralex
Aleirify
Nocetin
Sadepril
Merlopam

Aripiprazol
Aripiprazol diindikasikan untuk pengobatan
1. Scizoprenia
2. Acute Treatment of Manic and Mixed Episodes associated with Bipolar I Disorder\
Contraindications
Aripiprazole is contraindicated in patients with a history of a hypersensitivity reaction to
aripiprazole. Reactions have ranged from pruritus/urticaria to anaphylaxis [see ADVERSE
REACTIONS (6.2)].

Aripiprazol
Peringatan Penting:
Peringatan penting untuk pasien yang memiliki depresi
Berdasarkan studi klinis, terdapat risiko yang lebih besar pada sebagian kecil pasien anak,
remaja, dan dewasa muda yang menggunakan aripiprazol bersamaan dengan antidepresan,
memiliki kecenderungan berfikir/berencana/mecoba untuk menyakiti diri ataupun bunuh diri.
Meskipun demikian, para ahli belum yakin seberapa besar risiko itu timbul dan seberapa
penting risiko tersebut dijadikan pertimbangan dalam menentukan penggunaan antidepresan
pada pasien anak dan remaja. Anak dibawah 18 tahun normalnya tidak membutuhkan
aripiprazol untuk mengatasi depresi, tetapi pada kasus tertentu, dokter dapat memutuskan
bahwa aripiprazol adalah pengobatan terbaik untuk mengatasi kondisi pasien anak tersebut.
Penting untuk diketahui bahwa kesehatan mental dapat berubah secara tak terduka ketika
menggunakan aripiprazol atau antidepresan lainnya bahkan pada pasien dewasa lebih dari 24
tahun. Kecenderungan bunuh diri dapat timbul terutama pada awal pengobatan dan kapan pun
ketika dosis ditingkatkan ataupun diturunkan. Pasien, keluarga atau caregiver harus segera
menghubungi dokter ketika mengalami:
-

Depresi baru ataupun depresi yang memburuk

Pikiran untuk menyakiti atau bunuh diri, atau berencana atau mencoba melakukan hal

tsb
Kecemasan yang ekstrim
Agitasi
Serangan panik
Susah tidur
Sifat agresif
Sifat lekas marah
Bertindak tanpa berfikir
Kegelisahan yang berat
Mania

Be sure that your family or caregiver knows which symptoms may be serious so they can call the
doctor if you are unable to seek treatment on your own.

Your healthcare provider will want to see you often while you are taking aripiprazole, especially at
the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.
No matter what your age, before you take an antidepressant, you, your parent, or your caregiver
should talk to your doctor about the risks and benefits of treating your condition with an
antidepressant or with other treatments. You should also talk about the risks and benefits of not
treating your condition. You should know that having depression or another mental illness greatly
increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has
or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or
mania or has thought about or attempted suicide. Talk to your doctor about your condition,
symptoms, and personal and family medical history. You and your doctor will decide what type of
treatment is right for you.

Mengapa obat ini diresepkan?

Aripiprazol digunakan untuk mengobati:
1. Symptom schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of
interest in life, and strong or inappropriate emotions) pada pasien dewasa dan remaja 13
tahun
2. Kelainan Bipolar: Mania ataupun mixed episodes (symptom mania dan depresi yang terjadi
secara bersamaan)
3. Depresi
Aripiprazol juga digunakan sebagai antidepresan untuk mengatasi depresi ketika symptom
tidak dapat dikontrol dengan antidepresan tunggal.
4. Kelainan Autis: pada pasien anak 6-17 tahun
Aripiprazol tergolong antipsikotik atipikal. Bekerja dengan mengubah aktivitas senyawa endogen
tertentu di dalam otak.
Aripiprazole may help control your symptoms, but will not cure your condition. It may take 2 weeks or
longer before you feel the full benefit of aripiprazole. Continue to take aripiprazole even if you feel
well. Do not stop taking aripiprazole without talking to your doctor.

nteractions between your selected drugs

fuoxetine aripiprazole
Applies to: fluoxetine, aripiprazole
FLUoxetine may increase the blood levels and effects of ARIPiprazole. This can make
you more likely to develop side effects such as drowsiness, seizure, Parkinson-like
symptoms, abnormal muscle movements, and low blood pressure. You may need a

dose adjustment or more frequent monitoring by your doctor to safely use both
medications. Contact your doctor if you experience agitation, aggression, confusion,
convulsions, muscle spasm, or movements that you can't stop or control such as lip
smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching,
jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor,
jitteriness, restlessness, pacing, and foot tapping. Also be alert to symptoms of low
blood pressure such as dizziness, lightheadedness, fainting, and/or increased pulse or
heart rate. Avoid driving
or operating hazardous machinery until you know how

these medications affect you, and use caution when getting up from a sitting or lying
position, especially at the beginning of treatment or after an increase in dose of
ARIPiprazole. It is important to tell your doctor about all other medications you use,
including vitamins and herbs. Do not stop using any medications without first talking to
your doctor.