TUGAS IMMUNOLOGI

RESPON IMUN TERHADAP TRANSPLANTASI

Adelia Handoko
NIM. 011514153013

PROGRAM STUDI ILMU KEDOKTERAN DASAR

PROGRAM MAGISTER FAKULTAS KEDOKTERAN
UNIVERSITAS AIRLANGGA
2015

DAFTAR ISI
Halaman
HALAMA SAMPUL.................................................................................

DAFTAR ISI .............................................................................................

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DAFTAR GAMBAR ................................................................................

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BAB 1. PENDAHULUAN
1.1 Latar Belakang.......................................................................

1.2 Rumusan Masalah..................................................................

1.3 Tujuan ...................................................................................

BAB 2. RESPON IMUN TERHADAP TRANSPLANTASI

2.1

Dasar genetik . ...................................................................

2.1.1

Histokompatibel dan histoinkompatibel.................

2.1.2

Antigen Histokompatibel Mayor............................

2.1.3

Antigen Histokompatibel Minor.............................

2.1.4

Antigen Histokompatibel non MHC.......................

Respon Imun Melawan Transplan......................................

2.3 Antigen Transplantasi.........................................................

2.4 Induksi Respon Imun Melawan Transplan..........................

2.5 Mekanisme Imun Penolakan Graft......................................

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2.2

2.5.1

Peran Seluler ..........................................................

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2.5.2

Peran Antibodi .......................................................

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2.6 Jenis Penolakan....................................................................

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2.6.1

Penolakan Hiperakut ..............................................

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2.6.2

Penolakan Akut ......................................................

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2.6.3

Penolakan Kronis ...................................................

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Kesimpulan.........................................................................

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DAFTAR PUSTAKA...............................................................................

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BAB 3. PENUTUP
3.1

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DAFTAR GAMBAR

Halaman
Gambar 1.1 Jumlah resipien graft di Amerika Serikat................................

Gambar 2.1 Genetik terhadap penolakan graft...........................................

Gambar 2.2 Rejeksi allograft pertama dan kedua.......................................

Gambar 2.3 Pengenalan dari MHC allogeneic oleh limfosit T ..................

Gambar 2.4 Pengenalan direk dan indirek .................................................

Gambar 2.5 Diagram proses keberhasilan atau kegagalan tandur .............

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Gambar 2.6 Peran sel T dalam penolakan graft .........................................

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Gambar 2.7 Dasar selular hipersensitifitas sel Th 1 dan Th 2 ...................

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Gambar 2.8 Mekanisme destruksi sasaran .................................................

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Gambar 2.9 Fase penolakan terhadap graft.................................................

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