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LAMPIRAN

Gambar 1. struktur proteoglikan

Gambar 2. Syndecan
Gambar 3. Agreccan

Gambar 4. Matriks ekstrasel

Gambar 5. Proteoglikan membran dasar

Gambar 6. Struktur perlekan


Gambar 7. Struktur agrin

Gambar 8. Struktur bamakan

Gambar 9. Proteoglikan jenis hyalektan

Gambar 10. Struktur versikan

Gambar 11. Struktur agrekan


Gambar 12. Struktur neurokan

Gambar 13. Struktur brevikan

Gambar 14. Proteoglikan jenis SLRPs (Small Leucine-Rich Proteoglycans)

Gambar 15. Struktur SLRPs (Small Leucine-Rich Proteoglycans)


Gambar 16. Struktur glukosamin

Gambar 17. Jalur pembentukkan heksosamin

Gambar 18. Jalur sintesis glukosamin dan turunannya


Gambar 19. Stuktur kondroitin

Gambar 20. Pembentukkan prekursor gula nukleotida


Gambar 21. Pembentukkan kondroitin

Gambar 22. Perbedaan tulang (A) dan tulang rawan (B)

Gambar 23. Komponen tulang rawan pada sendi


Gambar 24. Penyakit osteoartritis

Gambar 25. Ikatan O-glikosidat antara GalNAc dan Ser

Gambar 26. Ikatan N-glukosamin antara GlcNAc dan nitrogen amida pada Asn
Gambar 27. Jalur sintesis untuk pembentukan UDP-Gula dan PAPs

Gambar 28. Ringkasan struktur glikosaminoglikan dan pelekatanya pada protein inti
Gambar 29. Sifat Utama Glikosaminoglikan

Gambar 30. Struktur Asam Hialuronat

Gambar 31. Asam Hialuronat ditulang dan tulang rawan (Kartilago)

Gambar 32. Asam Hialuronat di dalam mata


Gambar33. Asam Hialuronat di dalam kulit

Gambar 34. Biosynthesis Hyaluronat

Gambar 35. Skema degradasi HA


Gambar 36. Perbedaan biosintesis heparin sulfat, kondroitin sulfat atau glikosaminoglikan dermatan
sulfat.
Gambar 37. Biosintesis Heparin/Heparan sulfat
Gambar 38. Degradasi heparin/heparan sulfat

Gambar 39. Perbedaan disakarida dermatan sulfat


Gambar 40. Degradasi dermatan sulfat

Gambar 41. Gambaran fungsi IdoA pada DS/CS. (A) peran IdoA pada penyimpanan sitokin growth
factor, (B) Borreliainfection, (C) atherosclerosis, (D) koagulasi, (E) P-selectin-dependent
leukocyte recruitment, (F) pengaktifan sitokin dan reseptor growth factor, dan (G)
pengarahan leukosit oleh ICAM.
Gambar 42. Struktur Keratan Sulfat

Gambar 43. Keratan Sulfat I

Gambar 44. Keratan Sulfat II


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