Mahasiswa Pendidikan Profesi Dokter

Departemen Ilmu Bedah

Fakultas Kedokteran Universitas Hasanuddin
Divisi Bedah Onkologi

Salivary Gland Anatomy and Physiology

Ismi Nuranggraeni Guntur

C014182142

Supervisor
dr. Indra, Sp.B(K)Onk

Makassar, Rabu 17 Maret 2021

 Apa itu Salivary Gland?
Glandula salivatorius / kelenjar saliva / kelenjar air liur

Kelenjar eksokrin yang berada di kepala, sekitar cavum

oris dan menghasilkan saliva yang berguna untuk memprot
eksi dan melubrikasi mukosa oral dan berperan dalam
tahap awal proses pencernaan

Sieroslawska, A. and Mytilinaios, D., 2021. Salivary glands. [online] Kenhub. Available at: <https://www.kenhub.com/en/library/anatomy/the-salivary-glands> [Accessed 16 March 2021].
 Apa itu Salivary Gland?
Glandula salivatorius / kelenjar saliva / kelenjar air liur

Kelenjar mayor

Kelenjar minor

Sieroslawska, A. and Mytilinaios, D., 2021. Salivary glands. [online] Kenhub. Available at: <https://www.kenhub.com/en/library/anatomy/the-salivary-glands> [Accessed 16 March 2021].
 Fungsi Saliva
Saliva is a seroumucinous liquid
Terdiri dari: 99,5% air + 0,5% elektrolit, mucus, glycoprotein, enzim

1. Membasahi mukosa cavum oris

2. Lubrikasi/melicinkan makanan
3. Pencernaan kimiawi karbohidrat dan lemak
4. Antimicrobial action
5. Mencegah kerusakan gigi
6. Membantu kemampuan sensasi “rasa” dari lidah

unFact!
F

Sieroslawska, A. and Mytilinaios, D., 2021. Salivary glands. [online] Kenhub. Available at: <https://www.kenhub.com/en/library/anatomy/the-salivary-glands> [Accessed 16 March 2021].
Luhulima, J. and Nyambe, H., 2016. Anatomi Sistem Digestivus. Makassar: Departemen Anatomi Fakultas Kedokteran Universitas Hasanuddin, p.83.
 Glandula Parotis
• Glandula saliva terbesar
• Berat sekitar + 15-30 gr
• Dibungkus oleh suatu kapsul
(parotid sheath)
• Vaskularisasi: a. temporalis superf
isial, a. maxillaris, cabang a. car
otis externa (a. fasialis tranversal),
v. retromandibula
• Innervasi: N. IX (nervus glossopha
ryngeal) dan nervus auriculotemp
oral
 Ductus excretorius parotideus
Stenson's duct

• Berdinding tebal, panjang + 5 cm

• Bermuara ke vestibulum
ginggivobuccal (depan gigi molar II)
Glandula Submandibularis
Glandula Sublingualis
 Mikrostruktur Salivary Gland

Unit sekretorius Unit ductal: Jaringan penghubung:

(Acini): Sel - Ductus intercalated - Sorrounding capsule
- Sel serous myoephitelial - Ductus striata - Tissue septae
- Ductus excretorius - Tissue element
- Sel mucous

Antonio Nanci; Tencate’s Oral Histology; 8th edition; 253-71

 Mikrostruktur Salivary Gland

Antonio Nanci; Tencate’s Oral Histology; 8th edition; 253-71

 Mikrostruktur Salivary Gland

Antonio Nanci; Tencate’s Oral Histology; 8th edition; 253-71

 Teori Neoplasm of Salivary Gland

Terdapat dua hipotesis terkait perkembangan neoplasma

glandula salivatorius:
1. Well-differentiated cells of the salivary gland unit form
the neoplasm of their differentiated counterpart. According
to this concept:
Acinar cells -> Acinous cell carcinoma
Striated duct cells -> Oncocytic tumors

Myers, E. and Ferris, R., 2007. Salivary gland disorders. Berlin: Springer.
 Teori Neoplasm of Salivary Gland

Excretory duct cells -> Squamous cell carcinoma and muco

epidermoid carcinoma
Intercalated duct -> Adenocarcinoma

2. Bicellular theory: Undifferentiated “reserve” cell

Myers, E. and Ferris, R., 2007. Salivary gland disorders. Berlin: Springer.
Thank you!

Mahasiswa Pendidikan Profesi Dokter

Departemen Ilmu Bedah
Fakultas Kedokteran Universitas Hasanuddin
Divisi Bedah Onkologi