HUBUNGAN ANTARA POLUSI ASAP PADA PEMBAKAR SATE

DENGAN DRY EYE SYNDROME DI KECAMATAN GUBENG SURABAYA

PROPOSAL TUGAS AKHIR

Diajukan Untuk Salah Satu Syarat Guna

Meraih Gelar Sarjan Kedokteran

Disusun oleh :

ESTI NUR HIDAYATI

11700446

PROGRAM STUDI KEDOKTERAN

FAKULTAS KEDOKTERAN
UNIVERSITAS WIJAYA KUSUMA SURABAYA

2018
 HALAMAN PERSETUJUAN UJIAN

PROPOSAL TUGAS AKHIR

Hubungan Antara Polusi Asap Pada Pembakar Sate Dengan Dry Eye
Syndrome Di Kecamatan Gubeng Surabaya

Diajukan Untuk Salah Satu Syarat Guna

Meraih Gelar Sarjana Kedokteran

Oleh:

Esti Nur Hidayati

NPM : 11700446

Menyetujui untuk diuji

Pada tanggal : 3 Mei 2018

Penguji I/Pembimbing, Penguji II,

(Budhi Setiawan, dr, M.kes, Dr) (Sri Lestari Utami, SSi, M.Kes)
NIK. 99 294 – ET NIK. 99289-ET
 HALAMAN PENGESAHAN

PROPOSAL TUGAS AKHIR

Hubungan Antara Polusi Asap Pada Pembakar Sate Dengan Dry Eye
Syndrome Di Kecamatan Gubeng Surabaya

Oleh:

Esti Nur Hidayati

NPM : 11700446

Telah diuji pada

Hari : ………….

Tanggal : ………….

Dan dinyatakan lulus oleh:

Penguji I/Pembimbing, Penguji II,

(Budhi Setiawan, dr, M.kes, Dr) (Sri Lestari Utami, SSi, M.Kes)
NIK. 99 294 – ET NIK. 99289-ET
 KATA PENGANTAR

Puji syukur penulis panjatkan kehadirat Tuhan Yang Maha Esa yang telah
melimpahkan rahmat dan Karunia-Nya sehingga penulis dapat menyelesaikan
pembuatan Proposal penelitian dengan judul : “Hubungan Antara Polusi Asap
Pada Pembakar Sate Dengan Dry Eye Syndrome Di Kecamatan Gubeng
Surabaya”
Proposal ini dibuat dalam rangka memenuhi salah satu syarat untuk kegiatan
penelitian guna memenuhi syarat memperoleh gelar sarjana kedokteran. Ucapan
terima kasih yang sebesar-besarnya penulis sampaikan kepada :
1. Prof. Dr Soedarto. DTM & Ph.D. Sp. Prak, selaku Dekan Fakultas Kedokteran
Universitas Wijaya Kusuma Surabaya yang telah memberi fasilitas dan
kesempatan bagi penulis menuntut ilmu di Fakultas Kedokteran Universitas
Wijaya Kusuma Surabaya.
2. Budhi Setiawan, dr,Mkes,Dr selaku pembimbing yang telah memberikan
bimbingan arahan, serta dorongan dalam menyelesaikan tugas akhir ini.
3. Bu Sri Lestari Utami, S.Si., M.Kes selaku penguji tugas akhir yang telah
memberikan kesempatan penulis untuk mempresentasikan hasil tugas akhir
yang sudah dibuat oleh penulis.
4. Segenap tim pelaksana tugas akhir yang telah memberikan fasilitas proses
penyelesaian proposal penelitian
5. Kedua orangtua yang telah memberikan doa dan dukungan sehingga penulis
dapat menyelesaikan tugas akhir ini
6. Semua pihak yang tidak mungkin disebut satu per satu yang telah membantu
dalam menyelesaikan Tugas Akhir ini.
Dalam penulisan Tugas Akhir ini penulis sadar bahwa masih banyak terdapat
kekurangan dan jauh dari sempurna oleh karena itu penulis mengharapkan segala
kritik dan saran dari pembaca demi menyempurnakan Tugas Akhir ini.

Surabaya, 30 April 2018

Penulis
 DAFTAR ISI

HALAMAN JUDUL
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i
HALAMAN PERSETUJUAN UJIAN
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ii
HALAMAN PENGESAHAN
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iii
KATA PENGANTAR
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iv
DAFTAR ISI
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v
DAFTAR GAMBAR
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vi

BAB I PENDAHULUAN
A. Latar belakang
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1
 B. Rumusan masalah
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4
C. Tujuan
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4
D. Manfaat hasil penelitian
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4

BAB II TINJAUAN PUSTAKA

A. Tear Film atau Lapisan Air Mata
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6
B. Sindroma Mata Kering
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8
1. Definisi Sindroma Mata Kering (DES)
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8
2. Klasifikasi Sindroma Mata Kering (DES)
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9
3. Epidemiology Sindroma Mata Kering (DES)
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13
4. Faktor Risiko Sindroma Mata Kering (DES)
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14
5. Patofisiologi Sindroma Mata Kering (DES)
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15
6. Gejala Klinis Sindroma Mata Kering (DES)
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17
7. Pemeriksaan Penunjang Sindroma Mata Kering (DES)
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18
8. Penatalaksanaan Sindroma Mata Kering (DES)
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21
9. Komplikasi Sindroma Mata Kering (DES)
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22
C. Patofisiologi Paparan Asap Mengakibatkan Terjadinya
Sindroma Mata Kering (DES)
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23

BAB III KERANGKA KONSEP DAN HIPOTESIS PENELITIAN

A. Kerangka konsep
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25
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B. Hipotesis penelitian
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26
C. Hipotesis Statistik
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26

BAB IV METODE PENELITIAN

A. Jenis penelitian
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27
B. Lokasi dan waktu penelitian
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27
C. Populasi dan sampel
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28
D. Variable penelitian
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30
E. Definisi operasional
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30
F. Prosedur Penelitian
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31
G. Analisis data
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34
DAFTAR PUSTAKA
 DAFTAR GAMBAR

Gambar II.1 Tear Film Normal beserta Komponennya

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8
Gambar II.2 Klasifikasi Dry Eye Syndrome
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12
Gambar III.1. Kerangka Konsep
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25
Gambar IV.1 Alur Penelitian
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31
 DAFTAR TABEL

Tabel II.1: Skema Derajat Mata Kering

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18
Tabel IV.1. Definisi Operasional
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30