Interval Trakeostomi Dengan Total Laringektomi Pada Pasien Kanker Laring Stadium III Dan IV

Sebagai
Faktor Risiko Kekambuhan Paska Radioterapi
WAHYU DWI K, Dr. dr. S.R. Indrasari, M.Kes., Sp.T.H.T.K.L (K)., FICS.; dr Dian Paramita Wulandari., M.Sc.,Sp.T.H.T
Universitas Gadjah Mada, 2019 | Diunduh dari http://etd.repository.ugm.ac.id/

DAFTAR ISI

HALAMAN JUDUL ....................................................................................... i

..LEMBAR PENGESAHAN .......................................................................... ii
PERNYATAAN ........................................................................................... iii
PRAKATA………………………………..…………………………..v
DAFTAR ISI ................................................................................................ vii
DAFTAR TABEL ........................................................................................ ix
DAFTAR GAMBAR .................................................................................... x

BAB I. PENDAHULUAN
A. Latar Belakang Masalah ............................................................................1
B. Perumusan Masalah ...................................................................................5
C. Pertanyaan Penelitian ................................................................................5
D. Tujuan Penelitian .......................................................................................5
E. Manfaat Penelitian .....................................................................................5
F. Keaslian Penelitian .....................................................................................6

BAB II. TINJAUAN PUSTAKA

A. Karsinoma Laring
1. Definisi.................................................................................................8
2. Epidemiologi. ......................................................................................8
3. Patofisiologi. .......................................................................................9
4. Tanda dan Gejala ...............................................................................12
5. Stadium..............................................................................................12
5.1 Tumor Supraglotis… ...............................................................12
5.2 Tumor Glotis… .......................................................................13
5.3 Tumor Subglotis… ..................................................................13
5.4 Penjalaran Ke Kelenjar Limfa .................................................13
5.5 Metastasis Jauh… ....................................................................14
5.6 Stadium....................................................................................14
6... Diagnosis. .........................................................................................15
7. Penatalaksanaan. ...............................................................................18
8. Komplikasi… ....................................................................................20
9. Kekambuhan…..................................................................................20
B. Kerangka Teori……………….………………………………………..22
C. Kerangka Konsep ...................................................................................23
D. Hipotesis .................................................................................................23

BAB III. METODE PENELITIAN

A. Rancangan Penelitian .............................................................................24
B. Waktu dan Tempat Penelitan..................................................................24
C
…. …
Po…
pu…
las…
i d.an Sampel Penelitian ..............................................................24

vii
Interval Trakeostomi Dengan Total Laringektomi Pada Pasien Kanker Laring Stadium III Dan IV
Sebagai
Faktor Risiko Kekambuhan Paska Radioterapi
WAHYU DWI K, Dr. dr. S.R. Indrasari, M.Kes., Sp.T.H.T.K.L (K)., FICS.; dr Dian Paramita Wulandari., M.Sc.,Sp.T.H.T
Universitas Gadjah Mada, 2019 | Diunduh dari http://etd.repository.ugm.ac.id/

D. Variabel Penelitian Dan Definisi Operasional Penelitian .......................25

E. Besar Sampel Penelitian ..........................................................................27
F. Jalannya Penelitian ...................................................................................28
G. Alur Penelitian. ........................................................................................29
H. Rencana Analisis Data.............................................................................30
I. Kelaikan Etik............................................................................................30

BAB IV HASIL DAN PEMBAHASAN

A.Karakteristik dan Subjek Penelitian… .....................................................32
1. Jenis Kelamin.....................................................................................33
2. Usia ....................................................................................................34
3. Faktor Risiko merokok ......................................................................35
4. Stadium Dan Kekambuhan… ............................................................35
5. Interval total laringektomi paska trakeostomi ...................................36

BAB V SARAN DAN KESIMPULAN .......................................................46

DAFTAR PUSTAKA. .................................................................................47
LAMPIRAN………………….……………………………………………50

viii
Interval Trakeostomi Dengan Total Laringektomi Pada Pasien Kanker Laring Stadium III Dan IV
Sebagai
Faktor Risiko Kekambuhan Paska Radioterapi
WAHYU DWI K, Dr. dr. S.R. Indrasari, M.Kes., Sp.T.H.T.K.L (K)., FICS.; dr Dian Paramita Wulandari., M.Sc.,Sp.T.H.T
Universitas Gadjah Mada, 2019 | Diunduh dari http://etd.repository.ugm.ac.id/

DAFTAR TABEL

Tabel 1 Keaslian Penelitian…………………………………………………7

Table 2 Karakteristik Subyek Penelitian…………………………………..33

Tabel 3 Waktu Tunggu Total laringektomi Paska Trakeostomi…………..37

ix
Interval Trakeostomi Dengan Total Laringektomi Pada Pasien Kanker Laring Stadium III Dan IV
Sebagai
Faktor Risiko Kekambuhan Paska Radioterapi
WAHYU DWI K, Dr. dr. S.R. Indrasari, M.Kes., Sp.T.H.T.K.L (K)., FICS.; dr Dian Paramita Wulandari., M.Sc.,Sp.T.H.T
Universitas Gadjah Mada, 2019 | Diunduh dari http://etd.repository.ugm.ac.id/

DAFTAR GAMBAR

Gambar 1 Kanker Laring…..........................................................................12

Gambar 2 Kerangka Teori ............................................................................22

Gambar 3 Kerangka Konsep… ....................................................................23

Gambar 4 Alur Penelitian… .........................................................................29

Gambar 5 Distribusi kambuh / tidak kambuh ..............................................37

Gambar 6 Grafik Kaplan Meier………………...………………………….39