REFERAT

DIAGNOSI DAN TATALAKSANA PREMATURE OVARIAN INSUFFICIENCY

Disusun oleh:
Haerun Nisa Siregar 1920221102

Pembimbing:
dr. Marinda Suzanta, C.Ht, D.MAS, F.ART, SpOG (K-fer)

KEPANITERAAN KLINIK DEPARTEMEN ILMU KEBIDANAN DAN PENYAKIT KANDUNGAN

FAKULTAS KEDOKTERAN UPN “VETERAN” JAKARTA
PERIODE 3 AGUSTUS 2020 – 15 AGUSTUS 2020
fisiologi
Definisi & Epidemiologi Premature Ovarian Insufficiency (POI) adalah
berhentinya menstruasi pada wanita dibawah 40 tahun
dengan karakteristik:
-Amenorrhoeae selama 4-6 bulan
-Hypergonadotropism (FSH >40 IU/L)
-Hypoesterogenism (Estradiol <50pmol/L)

Terjadi pada 1-4% Perempuan

1% pada perempuan 40 tahun
0,1% pada perempuan 30 tahun
1:10.000 pada perempuan 20 tahun

(Gupta, 2020)(Vojovic, et al,., 2012) (Nguyen etal, 2017)

 Etiologi

(Gupta et al., 2020)

CLINICAL MANIFESTATIO

(Gupta et al., 2020, Nguyen et al, 2017))

Algoritma
DIAGNOSIS
(Gupta et al., 2020, Nguyen et al, 2017,Weber, et al, 2017)
MANAGEM
ENT
GUIDLINE
(Gupta et al., 2020, Nguyen et al, 2017,Weber, et al, 2017)
 Daftar pustaka
Nguyen H, H. et al. (2020) Premature ovarian insufficiency in generak practic: American College of Obstetricians and Gynecologists. ACOG committee
Meeting the needs of woman. Available at: racgp.org.au (Accessed: 8 opinion no 556: Postmenopausal estrogen therapy: Route of
Agustus 2020). administration and risk of venous thromboembolism. Obstet Gynecol.
2013;121(4):887-90.
Gupta, A. et al. (2019) ‘Premature Ovarian Insufficiency. EMJ Repro Health,.
doi:  https://doi.org/10.33590/emjreprohealth/19-00041. Dul, A. et al. (2011) ‘Menopause’, Available at patophys.org (Accessed: 7
Agustus 2020)
Vujovic, S.et al. (2012) ‘Premature Ovarian Failures’, doi:
10.2298/SARH1212806V. Melmed, S. et al. (eds) (2016) Williams Textbook of Endocrinology. 13th edn.
Philadelphia: Elsevier Inc.
Persani, L. (2010) ‘The prolactin receptor: Genes involved in human premature
ovarian failure. Genes involved in human premature ovarian failure. vvv
doi: https://doi.org/10.1677/JME-10-0070.
Halperin Rabinovich, I. et al. (2013) ‘Clinical guidelines for diagnosis and
treatment of prolactinoma and hyperprolactinemia’, Endocrinología y
Nutrición (English Edition). SEEN, 60(6), pp. 308–319. doi:
10.1016/j.endoen.2012.11.009.