Monday, January 11th 2021

What is the best treatment approach

for severe blepharitis?

Dea Vilia Siswoyo, S.Ked

2011901006

Pembimbing:
dr. Dasrinal, Sp.M
KEPANITERAAN KLINIK SENIOR
BAGIAN ILMU PENYAKIT MATA
FAKULTAS KEDOKTERAN
UNIVERSITAS ABDURRAB
RSUD KOTA DUMAI
2020
Abstrak
• Blepharitis adalah salah satu yang paling
umum gangguan yang ditemui dalam
oftalmologi.

• Blepharitis dapat bermanifestasi sebagai

penyakit anterior dan / atau posterior.

• Tiga kunci strategi harus ditangani dalam

pengobatan blepharitis: (1) manajemen
gejala, (2) mengontrol peradangan yang ada
mencegah kerusakan jangka panjang, dan (3)
pencegahan kekambuhan. 
Informasi Berbasis Bukti yang Relevan
American Academy of Ophthalmology mengklasifikasikan
blepharitis menjadi blepharitis anterior, blepharitis posterior,
dan kombinasi keduanya.

Blepharitis anterior seperti seboroik atau penyakit stafilokokus.

Blepharitis posterior mengacu pada disfungsi kelenjar meibom.

Pasien sering mengeluh kemerahan, iritasi, terbakar, gatal, bulu

mata mengeras, penglihatan kabur atau berfluktuasi, fotofobia
dan intoleransi lensa kontak.

Setelah jenis blepharitis telah dikategorikan, saatnya untuk

menargetkan spesifik patofisiologi dengan pengobatan yang tepat.
Tujuan pengobatan: (1) manajemen gejala, (2) mengontrol
peradangan yang ada untuk mencegah kerusakan jangka panjang,
dan (3) pencegahan kekambuhan.
 Hasil

Pengobatan Blepharitis Anterior

intervensi yang pertama: edukasi pasien dan menjaga
kebersihan kelopak mata (kompres hangat dan
menggosok kelopak mata).
Kompres harus dilakukan setidaknya 2x/hari di awal
perjalanan penyakit dan dapat dilakukan setiap hari
setelah gejala terkontrol.
Membersihkan daerah kulit periokular dan alis dengan
lembut, sampo antijamur non-deterjen sebagai tambahan
kompres hangat dan menggosok kelopak mata.

Air mata buatan bisa meredakan gejala substansial.

Formulasi yang lebih tebal seperti gel dan salep bisa
digunakan untuk kasus yang lebih parah.
 Hasil

Pengobatan Blepharitis Anterior

Baru-baru ini, antibiotik makrolida (termasuk azitromisin
dan eritromisin) memiliki sifat anti-inflamasi sebagai
tambahan untuk sifat anti infeksi.
Azitromisin topikal digunakan dua kali sehari pada pasien
fase akut untuk kontrol cepat bakteri dan peradangan
tetapi dapat digunakan sekali sehari pada terapi jangka
panjang untuk pencegahan.
Perawatan untuk rosacea membutuhkan terapi jangka
panjang. Terapi dengan doksisiklin biasanya dimulai pada
100 mg sekali atau dua kali sehari selama jangka waktu 6-
12 minggu.
Kasus blepharitis yang parah seringkali memerlukan
pengobatan kortikosteroid topikal jangka pendek, seperti
fluorometholone 0,1% atau loteprednol 0,5%.
Pengobatan
Blepharitis Posterior
Mirip dengan blepharitis anterior, tujuan pertama
terapi harus perbaikan lingkungan lokal. Edukasi
pasien, kebersihan kelopak mata, kompres hangat,
dan pijat kelopak mata harus menjadi dasar
pengobatan dengan disfungsi kelenjar meibom.

Kompres hangat biasanya diaplikasikan dengan

waslap yang dibasahi air hangat,

suplementasi oral dengan asam lemak omega-3

esensial. Dengan dosis antara 2000 hingga 6000
miligram per hari. Pereda gejala lebih lanjut dengan
film air mata pelumas topikal, karena mata kering
seringkali menjadi faktor komplikasi dalam blepharitis
posterior.

Tetrasiklin dan azitromisin sebagai sifat anti-

inflamasi. penggunaan kortikosteroid topikal untuk
kontrol yang lebih cepat dan lengkap pada
peradangan kasus yang parah.
 Kesimpulan & Saran

Blepharitis adalah kondisi mata yang umum dan sering menjadi

penyebab kunjungan. Tanda dan gejala sering mencerminkan
Contents mata kering, infeksi / infestasi, dan peradangan.

Semua terapi harus dimulai dengan edukasi pasien,

kebersihan kelopak mata dan kompres hangat.
Penatalaksanaan gejala yang tersisa dapat dilakukan dengan
topikal dan terapi obat sistemik.
Contents
Peradangan juga harus dikontrol untuk memperbaiki gejala
dan mencegah kerusakan jangka panjang. Terapinya bisa
disesuaikan dengan rejimen yang difokuskan mencegah
kekambuhan.
Contents
Critical Appraisal:
1. Penulis Jurnal:
Paramdeep Mand, MD1; Mark J. Mannis, MD, FACS2
 

2. Institusi:
1. Clinical Fellow, Cornea, External Disease, and Refractive Surgery, UC Davis Eye Center, University of California,
Davis
2. Professor and Chair, Department of Ophthalmology & VIsion Science, UC Davis Eye Center.

3. Tahun Publish:
2014
 
4. Keterangan Pendukung :
 
Referensi dari 28 jurnal sejak tahun 1946-2014
 
5. Transparansi Penanggung Jawab
 
Mark J. Mannis, MD, FACS Department of Ophthalmology & VIsion Science UC Davis Eye Center 4860 Y St, Suite
2400 Sacramento, CA 95817 E-mail: mjmannis@ucdavis.edu
6. Transparansi Sponsor:
Tidak ada sponsor
7. Kebijakan Iklan dan Editorial
 
Tidak dicantumkan
 
8. Unsur Pelengkap:
 
DOI: https://doi.org/10.15324/vpa.v13i3.208
 
9. Kerahasiaan:
 
Tidak disebutkan
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Color &
Line Color

FREE
PPT
TEMPLATES
www.allppt.com
 Fully Editable Icon Sets: C

You can Resize without

losing quality
You can Change Fill
Color &
Line Color

FREE
PPT
TEMPLATES
www.allppt.com