PROPOSAL PENELITIAN

EFEK PLATELET-RICH PLASMA TERHADAP KEMAMPUAN

MIGRASI SEL HDF CD105

Disusun Oleh:

Desya Billa Kusuma Anindhira

NPM 1102014070

Proposal penelitian ini diajukan dalam rangka memenuhi persyaratan

tugas akhir pendidikan Sarjana Kedokteran

FAKULTAS KEDOKTERAN
UNIVERSITAS YARSI
2017
 DAFTAR ISI
LEMBAR PERSETUJUAN ............................................................................................... i
DAFTAR ISI ...................................................................................................................... ii
DAFTAR SKEMA ............................................................................................................. iv
DAFTAR TABEL .............................................................................................................. v

BAB 1 PENDAHULUAN
1.1 Latar Belakang Masalah ................................................................................... 1
1.2 Rumusan Masalah ............................................................................................. 2
1.3 Pertanyaan Penelitian ....................................................................................... 2
1.4 Tujuan Penelitian .............................................................................................. 2
1.5 Manfaat Penelitian ............................................................................................ 2

BAB 2 TINJAUAN PUSTAKA

2.1. Kajian Pustaka
2.1.1 Platelet Rich Plasma (PRP) ....................................................................... 3
2.1.2 Human Dermal Fibroblast (HDF ............................................................... 4
2.1.3 Penyembuhan Luka (Wound Healing) ...................................................... 5
2.1.4 Sel Punca Mesenkim ................................................................................. 5
2.1.5 Migrasi Sel ................................................................................................ 5
2.2 Kerangka Teori ................................................................................................. 6
2.3 Kerangka Konsep ............................................................................................. 6
2.4 Perumusan Hipotesis ........................................................................................ 7
2.5 Definisi Operasional ......................................................................................... 7
BAB 3 METODE PENELITIAN
3.1 Jenis Penelitian ................................................................................................. 8

3.2 Rancangan Penelitian ........................................................................................ 8

3.3 Populasi Pengumpulan Data ............................................................................ 8

3.4 Sampel Pengumpulan Data ............................................................................... 8

3.5 Cara Penetapan Sampel ..................................................................................... 8

3.6 Penetapan Besar Sampel ................................................................................... 8

3.7 Jenis Data .......................................................................................................... 8

ii
 3.8 Cara Pengumpulan dan Pengukuran Data ........................................................ 9

3.9 Instrumen Pengumpulan Data ........................................................................... 9

3.10 Analisis Data ................................................................................................... 9

3.11 Alur Penelitian ................................................................................................ 10

3.12 Jadwal Penelitian ............................................................................................ 13

DAFTAR PUSTAKA. ........................................................................................................ 14

iii
DAFTAR SKEMA

Skema 2.1 Kerangka Teori. ................................................................................................ 6

Skema 2.2 Kerangka Konsep. ............................................................................................. 6

Skema 3.1 Alur Penelitian .................................................................................................. 10

iv
DAFTAR TABEL

Tabel 2.1 Definisi Operasional. .......................................................................................... 7

Tabel 3.1 Jadwal Penelitian ................................................................................................ 13