vi

DAFTAR ISI

Lembar Pengesahan............................................................................................... i
Abstrak.................................................................................................................. ii
Abstract.................................................................................................................. iii
Kata Pengantar....................................................................................................... iv
Daftar Isi................................................................................................................ vi
Daftar Gambar....................................................................................................... viii
Daftar Tabel........................................................................................................... ix
Daftar Lampiran.................................................................................................... x

BAB 1 PENDAHULUAN................................................................................ 1
1.1. Latar Belakang...................................................................................... 1
1.2. Rumusan Masalah................................................................................. 2
1.3. Tujuan Penelitian.................................................................................. 3
1.4. Manfaat Penelitian................................................................................ 3

BAB 2 TINJAUAN PUSTAKA....................................................................... 4

2.1. DefinisiAcne vulgaris............................................................................ 4
2.2. Epidemiologi Acne................................................................................ 4
2.3. Klasifikasi Acne vulgaris...................................................................... 5
2.4. Faktor Resiko........................................................................................ 8
2.5. Patogenesis............................................................................................ 9
2.5.1. Hiperkornifikasi.................................................................................... 9
2.5.2. Aktivitas Abnormal Mikroba................................................................ 10
2.5.3. Faktor Inflamasi.................................................................................... 11
2.5.4. Faktor Hormonal................................................................................... 12
2.6. Gambaran Klinis................................................................................... 14
2.7. Penatalaksanaan.................................................................................... 16

BAB 3 KERANGKA KONSEP DAN DEFINISI OPERASIONAL............... 18

3.1. Kerangka Konsep Penelitian................................................................. 18
3.2. Definisi Operasional............................................................................. 18

BAB 4 METODE PENELITIAN ..................................................................... 21

4.1. Jenis Penelitian...................................................................................... 21
 vii

4.2. Waktu dan Tempat Penelitian............................................................... 21

4.3. Populasi dan Sampel Penelitian............................................................ 21
4.3.1. Populasi................................................................................................. 21
4.3.2. Sampel................................................................................................... 21
4.4. Metode Pengumpulan Data................................................................... 21
4.5. Metode Analisis Data............................................................................ 22

BAB 5 HASIL DAN PEMBAHASAN ............................................................ 23

5.1. Hasil Penelitian .................................................................................... 23
5.1.1. Deskripsi Lokasi Penelitian.................................................................. 23
5.1.2. Karakteristik Individu........................................................................... 23
5.1.3. Distribusi Karakteristik sampel dan Analisa Data................................ 23
5.2. Pembahasan........................................................................................... 27
5.2.1. Gambaran Distribusi Acne vulgaris berdasarkan jenis kelamin........... 27
5.2.2. Gambaran Distribusi Acne vulgaris berdasarkan usia.......................... 28
5.2.3. Gambaran Distribusi Acne vulgaris berdasarkan tingkat keparahan.... 29
5.2.4. Gambaran Distribusi Acne vulgaris berdasarkan pekerjaan................. 29
5.2.5. Gambaran Distribusi Acne vulgaris berdasarkan pemakaian kosmetik 29
5.3. Keterbatasan Penelitian......................................................................... 30

BAB 6 KESIMPULAN DAN SARAN............................................................. 31

6.1. Kesimpulan........................................................................................... 31
6.2. Saran..................................................................................................... 32

DAFTAR PUSTAKA............................................................................................ 33

LAMPIRAN
 viii

DAFTAR GAMBAR

Nomor Judul Halaman

2.1. Enam Area Predileksi Acne 7
2.2. Patogenesis Acne vulgaris 9
2.3. Aspek Moderen Patogenesis Acne 11
2.4. Proses Inflamasi pada Fase Awal dan Akhir Acne 12
2.5. Faktor Hormonal terhadap Terjadinya Acne 13
2.6. Jenis-jenis Lesi Acne 14
3.1. Kerangka Konsep Penelitian 18
 ix

DAFTAR TABEL

Nomor Judul Halaman

2.1. Tabel Penentuan Tingkat Keparahan Acne 7

5.1 Gambaran distribusi frekuensi penderita Ance vulgaris 24
5.2 Karakteristik Acne vulgaris berdasarkan jenis kelamin 25
 x

DAFTAR LAMPIRAN

Lampiran 1 Daftar Riwayat Hidup

Lampiran 2 Surat Persetujuan Komisi Etik Tentang Pelaksanaan Penelitian

Bidang Kesehatan

Lampiran 3 Surat Izin Studi Pendahuluan

Lampiran 4 Surat Izin Studi Penelitian

Lampiran 5 Data SPSS

Lampiran 6 Hasil Output SPSS