immunoglobulin

Dosen pengampu:
Dra.Apt.Syilfia Hasti,M.Farm
 Kelompok 6

1. PUJI YANA (2101190)

2.
RANI MULYANI (2101192)

3. RESTIA SEPTI (2101193)

4. RIL AISYAH (2101194)

5. RISTYVA ALIYDA (2101195)

IMMUNOGLOBULIN
DEFENISI
01 Immunoglobulin atau Antibodi merupakan suatu
fraksi plasma (serum) yang bereaksi secarakhusus
dengan antigen yang merangsang produksinya. Berat
molekulnya dari terendah sekitar150.000 (angka
sedimentasi 7S) untuk komponen IgG hingga fraksi
dengan berat molekul900.000 (19S) untuk IgM
STRUKTUR
Imunoglobulin merupakan rangkaian 4 rantai polipeptida yang terdiri dari 2
rantai “berat”(Heavy Chain=H) dan 2 rantai “ringan” (Light Chain= L) yang
02 tersusun secara simetris dan saling berhubungan satu sama lainnya melalui
ikatan disulfida (Interchain Disulfide Bonds).Struktur dasar ini ditemukan oleh
Porter
Tabel.Immunoglobulin Manusia
JENIS-JENIS IMMUNOGLOBULIN

1. ImunoglobulinG (IgG)
2. Imunoglobulin A (IgA)
3. Imunoglobulin M (IgM
4. ImunoglobulinE (IgE)
5. ImunoglobulinD (IgD)
 FUNGSI

ImmunoglobulinG
Melindungi tubuh dari infeksi dengan Immunoglobulin M
cara “mengikat” kuman yang telah di -Antibodi ini bereaksi dengan virus atau
hadapi sebelumnya bakteri yang baru pertama kali
menyerang tubuh -Sebagai benteng
Immunoglobulin A pertahanan paling pertama untuk
-Mencegah kuman patogen melawan virus atau bakteri.
-menyerang permukaan sel mukosa
- Tidak efektif dlam mengikat komplemen
- Bersifat bakterisida dengan kondisinya
sebagai lysozim yang ada dalam cairan sekretori yang
mengandung IgA
- Bersifat antiviral dan glutinin yang efekti
Lanjutan fungsi
Immunoglobulin E
-Melepaskan mediator dari sel mast dan
basofil setelah seseorang terkena allergen
-Pertahanan utama thd infeksi cacing (dengan
melepas enzim dari eosinofil)
Immunoglobulin D
mencegah agar ibu rhesus-negatif
tidak membentuk antibodi terhadap
sel janin rhesus-positif yang
memasuki sirkulasi ibu ketika
dilahirkan atau ketika abortus
Idiom

Did you know that when you are told "you are
over the Moon" you are not really 384,000 km
(or so) away from the person talking to you, but
that you are very pleased?
"Amazing" words. Vocabulary

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● It is the one used to end the story.
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Order your ideas in a simple way
Order your main and secondary ideas in simple sentences:

Main ideas

Secondary ideas
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Write down possible words that can be used with main ideas and cool words:

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