DAFTAR ISI

Halaman

Halaman Judul ............................................................................................................ ii

Lembar Persetujuan ................................................................................................... iii

Kata Pengantar ........................................................................................................... iv

Daftar Isi ..................................................................................................................... vii

Daftar Tabel ................................................................................................................ x

Daftar Gambar ........................................................................................................... xi

Daftar Singkatan ......................................................................................................... xii

BAB I PENDAHULUAN ........................................................................................... 1

1.1 Latar Belakang ................................................................................... 4

1.2 Rumusan Masalah ............................................................................. 4
1.3 Tujuan Penelitian............................................................................... 4
1.3.1 Tujuan Umum ....................................................................... 4
1.3.2 Tujuan Khusus ...................................................................... 4
1.4 Manfaat Penelitian ............................................................................ 5
1.4.1 Manfaat Bagi Perkembangan Ilmu Pengetahuan................. 5
1.4.2 Manfaat Bagi Tenaga Kesehatan .......................................... 5

BAB II TINJAUAN PUSTAKA ................................................................................... 6

2.1 Anatomi Fisiologi Kulit....................................................................... 6
2.1.1 Anatomi Kulit ........................................................................ 6
2.1.2 Fisiologi Kulit......................................................................... 9
2.1.3 Kerusakan Integritas Jaringan .............................................. 9
2.2 Luka Bakar ......................................................................................... 10
2.2.1 Definisi Luka Bakar ............................................................... 10
2.2.2 Etiologi Luka Bakar ............................................................... 10
2.2.3 Klasifikasi Luka Bakar ............................................................ 11
2.2.3.1 Berdasarkan Kedalaman Luka Bakar ..................... 11
2.2.3.2 Berdasarkan Luas Luka Bakar ................................ 14
2.2.3.3 Berdasarkan Berat Ringannya Luka Bakar ............ 17
2.2.4 Patofisiologi Luka Bakar........................................................ 19
2.2.4.1 Perubahan patofisiologi yang Terjadi Pada
Kulit dan perubahan Fisiologi ............................. 20
2.2.4.1.1 Perubahan Anatomi Patologi Kulit ........ 20
2.2.4.1.2 Perubahan Pada Pembuluh Darah......... 21

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 2.2.5 Manifestasi Klinis Luka Bakar ............................................... 27
2.2.6 Penyembuhan Luka Bakar .................................................... 28
2.2.6.1 Fase Inflamasi ........................................................ 29
2.2.6.2 Fase Proliferasi ...................................................... 33
2.2.6.3 Fase Remodeling ................................................... 35
2.2.7 Faktor-faktor yang mempengaruhi penyembuhan Luka
Bakar ..................................................................................... 37
2.2.8 Morfologi Neutrofil .............................................................. 41
2.2.9 Perawatan Luka Bakar .......................................................... 44
2.2.9.1 Prinsip Pemilihan Balutan ..................................... 45
2.2.9.2 Moisture Wound Management............................. 45
2.2.9.3 Manfaat Perawatan Luka Moist ............................ 46
2.2.9.4 Prosedur Balutan Basah Lembab .......................... 47
2.2.9.5 Perhitungan Kadar Air Dalam Bahan..................... 48
2.2.9.6 Alat Pengukur Kelembaban ................................... 59
2.2.10 Betaine Polihexanide 0,1% ................................................... 50

BAB III KERANGKA KONSEPTUAL DAN HIPOTESIS PENELITIAN............................. 53

3.1 Kerangka Konseptual......................................................................... 53
3.2 Hipotesis Penelitian ........................................................................... 54

BAB IV METODE PENELITIAN .................................................................................. 55

4.1 Desain Penelitian ............................................................................... 55
4.2 Sampel .............................................................................................. 55
4.2.1 Kriteria Sampel ..................................................................... 55
4.2.2 Cara Perhitungan Sampel ..................................................... 57
4.3 Tempat dan Waktu Penelitian........................................................... 59
4.4 Variabel Penelitian ............................................................................ 59
4.4.1 Variabel Bebas ...................................................................... 59
4.4.2 Variabel Terikat .................................................................... 59
4.5 Alat dan Bahan .................................................................................. 59
4.5.1 Alat dan Bahan Untuk Eksplorasi Tingkat Kelembaban ....... 59
4.5.2 Alat dan Bahan Untuk Sterilisasi .......................................... 59
4.5.3 Alat dan Bahan Untuk Pembuatan Luka Bakar Derajat IIA .. 60
4.5.4 Alat dan Bahan Untuk Perawatan Luka Bakara Derajat IIA .. 60
4.5.5 Alat dan Bahan Untuk Membuat Preparat Histologi Jaringan
Kulit....................................................................................... 60
4.6 Prosedur Penelitian ........................................................................... 60
4.6.1 Prosedur Eksplorasi Tingkat Kelembaban Balutan Luka....... 60
4.6.2 Prosedur Sterilisasi ............................................................... 63
4.6.2 Prosedur Pembuatan Luka Bakar Derajat IIA ....................... 63
4.6.3 Prosedur Perawatan Luka Bakar Derajat IIA ........................ 64
4.7 Definisi Operasional ............................................................. 67
4.8 Prosedur Pengumpula Data.................................................. 68
4.8.1 Tehnik Pengumpulan Data .................................... 68
4.8.2 Metode pengumpulan Data .................................. 69

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 4.8.3 Identifikasi Jumlah Neutrofil ................................. 69
4.9 Alur Penelitian ............................................................................... 73
4.10 Analisa Data....................................................................................... 74
4.10.1 Uji Normalitas Data .............................................................. 74
4.10.2 Uji One Way Anova............................................................... 74
4.10.3 Uji Perbandingan Berganda .................................................. 75

DAFTAR PUSTAKA....................................................................................................... 76

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