TUGAS DASAR-DASAR HIGIENE INDUSTRI

“ANALISIS SAFETY DATA SHEET BAHAN KIMIA NIACINAMIDE

(NICOTINAMIDE)”

Disusun Oleh :

AURILIA DEVA SHAFANISSA

A/R0221018

PROGRAM DIPLOMA 4 KESELAMATAN DAN KESEHATAN KERJA

FAKULTAS KEDOKTERAN UNIVERSITAS SEBELAS MARET
SURAKARTA
2021
 Safety Data Sheet/Material Safety Data Sheet (SDS/MSDS)

Material Safety data Sheet (MSDS) atau dalam Bahasa Indonesia biasa disebut sebagai
Lembar Data Keamanan Bahan merupakan dokumen yang penting untuk menunjang keselamatan
kerja di laboratorium, atau di lingkungan kerja manapun. MSDS berisi tentang informasi mengenai
prosedur dan petunjuk yang tepat dan harus diketahui oleh pekerja, terkait dengan petunjuk
penanganan, penyimpanan, dan prosedur pembuangan bahan kimia setelah digunakan. Pada
umumnya MSDS selalu disertai dalam setiap pembelian bahan kimia terkait, hal ini sesuai dengan
peraturan seperti keputusan Menteri Kesehatan nomor 472 tahun 1996, keputusan Menteri tenaga
kerja nomor 187 tahun 1999, PP 74 tahun 2001 tentang B3 serta keputusan Menteri perindustrian
no. 87 tahun 2009 tentang Global Harmonize System (GHS). Setiap personil yang akan
menggunakan bahan kimia tersebut dainjurkan untuk membaca MSDS tersebut demi keamanan
pekerja. Bagian-bagain yang terdapat pada MSDS bisa berbeda-beda, dan umumnya harus
mengandung informasi tentang :
a. Identitas semua ingredient yang terkandung <1% jika memiliki sifat bahaya terhadap
kesehatan atau jika dapat melepaskan bahan berbahaya melebihi nilai ambang batas
(NAB) yang ditentukan.
b. Bahaya kesehatan termasuk tanda-tanda dan gejala jika terpajan.
c. Kondisi medis yang terjadi jika terpajan.
d. Rute utama masuk kedalam tubuh (route of entry)
e. Bahaya kanker jika ada.
f. Sifat fisik dan kimia
g. Batas pajanan (NAB)
h. Peringatan bahaya
i. Prosedur pembersihan
j. Pertolongan pertama atau darurat

Sedangkan untuk bagian-bagian yang terdapat pada MSDS, menurut format standard dari
ANSI yaitu sebagai berikut :
 1. Bagian 1 memberikan informasi rinci mengenai nama, CAS number (no. registrasi
internasional), nama perusahaan yang mengeluarkan, dan nomor kontak darurat. CAS
number adalah nomor unik yang diberikan oleh ACS (Chemical Abstracts Service)
pada setiap bahan kimia yang sudah diketahui, ditemukan, atau disintesis.
2. Bagian 2 menunjukan bahan berbahaya OSHA, dan mungkin meliputi bahan kunci
lainnya serta ambang batas.
3. Bagian 3 menunjukan pengaruh terhadap kesehatan.
4. Bagian 4 menyediakan ukuran pertolongan pertama yang perlu diberikan pada paparan
bahan kimia tersebut.
5. Bagian 5 menampilkan besarnya penanganan pemadam kebakaran yang perlu diambil.
6. Bagian 6 menujukkan prosedur yang perlu diambil jika kecelakaan terhadap bahan
tersebut terjadi.
7. Bagian 7 menunjukkan informasi penanganan dan penyimpanan bahan kimia. Bagian
tersebut merupakan bagian yang penting.
8. Bagian 8 memberikan garis besar batas regulator paparan bahan kimia, biasanya nilai
PEL maksimum.
9. Bagian 9 memberikan informasi sifat fisik dan kimia bahan.
10. Bagian 10 memberikan informasi kreaktifan dan kestabilan.
11. Bagian 11 memberikan informasi toksisitas akun dan kronis.
12. Bagian 12 menunjukkan baik ekotoksisitas dan bahaya bahan terhadap lingkungan.
13. Bagian 13 menyediakan saran pembuangan bahan kimia.
14. Bagian 14 memberikan informasi pendistribusian yang dibutuhkan.
15. Bagian 15 menunjukan garis besar informasi regulatori, seperti kode bahaya.
16. Bagian 16 memberikan informasi mengenai label peringatan, tanggal penyiapan atau
revisi, serta pihak yang mengeluarkan MSDS.

Berikut ini merupakan contoh analisis terhadap laporan/lembar MSDS yang terletak pada
suatu bahan kimia.
 MSDS (Material Safety Data Sheet) Niacinamide

A. Identifikasi Jenis Produk

1. Nama Produk : Niacinamide, USP (Nicotinamide)
2. Product Code : 0377
3. Uese : Nutritional Agent, Vitamin, penggunaan luar

B. Identifikasi Informasi terkait Produk

Berdasarkan keterangan tentang bahan kimia niacinamide (nicotinamide)

yang tertera pada Safety Data Sheet di atas, dapat disimpulkan bahwa :

1. Pada section 2, dikatakan bahwa zat niacinamide ini dapat menyebabkan

keracunan apabila masuk ke dalam mulut dan akan berbahaya apabila
tertelan, selain itu, bahan kimia ini juga dapat menimbulkan iritasi yang cukup
serius pada mata.

Untuk menghindari permasalahan serius tersebut, maka disarankan untuk

menggunakan pelindung mata dan pelindung wajah ketika menggunakan
bahan kimia tersebut. Selain itu disarankan pula untuk mencuci tangan dan
membersihkan tubuh setelah menggunakan bahan kimia tersebut.

Pada section 2 tersebut, dinyatakan juga perilaku yang harus kita lakukan
segera setelah mata kita terkontaminasi bahan kimia tersebut. Selain pada
section 2, pada section 4 pun disebutkan pula pertolongan pertama yang dapat
kita lakukan apabila tubuh kita, bagian dari tubuh kita terkontaminasi oleh
bahan kimia tersebut.

2. Pada section 5,disebutkan petunjuk Tindakan apabila terjadi kebakaran akibat

bahan kimia berbahaya tersebut. Di dalamnya, disebutkan bahwa benda
mudah terbakar apabila berada pada temperature yang tinggi. Kemudian
disebutkan juga bahwa pembakaran yang berbahaya dapat sewaktu-waktu
timbul di bawah paparan api. Dijelaskan pula di dalamnya benda-benda atau
bahan yang dapat digunakan untuk memadamkan api yang timbul dari bahan
kimia tersebut dan alat-alat apa saja yang dibutuhkan untuk membantu
memadakannya. Begitu pula dengan section 6, yang didalamnya disebutkan
pula petunjuk Tindakan yang dapat dilakukan ketika terjadi bahaya-bahaya
lain yang timbul.
3. Pada section 7, disebutkan cara-cara penanganan dan penyimpanan bahan
yang mengandung niacinamide, dan anjuran-anjuran lain terkait penyimpanan
niacinamide tersebut, dimana penyimpanannya haruslah jauh dari kontak
dengan tubuh, dan selalu mencuci tangan setelah menggunakan bahan kimia
terkait. Penyimpanannya pun harus dijauhkan dari bahan-bahan lain yang
tidak kompatibel dengan niacinamide, dan harus terjaga dengan baik.

4. Pada section 9,dijelaskan tentang sifat-sifat kimia dan fisik dari niacinamide,
seperti, bentuk fisiknya yang padat, dan dijelaskan pula sifat kelarutan dari
bahan kimia tersebut. Di dalamnya juga dijelaskan beberapa hal lain seperti
suhu pengapian yang terletak pada 480°C atau 898°F, serta disebutkan pula
titik didih dari cairan tersebut, yaitu pada suhu 157°C atau 314.6°F, sedangkan
untuk titik bekunya berada pada suhu (128-131)°C atau (262.4- (267.4-
267.8)°F. Untuk titik nyala dari bahan tersebut yaitu terletak pada suhu 182°C
atau 359.6°F, dan untuk pH nya cenderung netral, yakni berada pada pH 6.0
hingga 7.5.
 SAFETY DATA SHEET

SECTION 1: PRODUCT IDENTIFICATION

PRODUCT NAME NIACINAMIDE, USP (Nicotinamide)

PRODUCT CODE 0377
SUPPLIER MEDISCA Inc.
Tel.: 1.800.932.1039 | Fax.: 1.855.850.5855
661 Route 3, Unit C, Plattsburgh, NY, 12901
3955 W. Mesa Vista Ave., Unit A-10, Las Vegas, NV, 89118
6641 N. Belt Line Road, Suite 130, Irving, TX, 75063
MEDISCA Pharmaceutique Inc.
Tel.: 1.800.665.6334 | Fax.: 514.338.1693
4509 Rue Dobrin, St. Laurent, QC, H4R 2L8
21300 Gordon Way, Unit 153/158, Richmond, BC V6W 1M2
MEDISCA Australia PTY LTD
Tel.: 1.300.786.392 | Fax.: 61.2.9700.9047
Unit 7, Heritage Business Park
5-9 Ricketty Street, Mascot, NSW 2020
MEDISCA UK Limited
Tel.: 0800.029.4641
33 St. James's Square, London, United Kingdom SW1Y 4JS
EMERGENCY PHONE CHEMTREC Day or Night Within USA and Canada: 1-800-424-9300
NSW Poisons Information Centre: 131 126
National Chemical Emergency Centre 44(0)1235239670
USES Nutritional Agent; Vitamin

SECTION 2: HAZARDS IDENTIFICATION

GHS CLASSIFICATION Acute Toxicity - Oral (Category 5)

Eye Irritation (Category 2A)
PICTOGRAM

SIGNAL WORD Warning

HAZARD STATEMENT(S)
ADVERSE PHYSIOCHEMICAL, HUMAN
HEALTH AND ENVIRONMENTAL
EFFECTS
PRECAUTIONARY STATEMENT(S)
May be harmful if swallowed.
Causes serious eye irritation.
Repeated exposure may cause skin dryness or cracking.
Prevention Wear eye and face protection.
Wash thoroughly after handling.
Response IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if
present and easy to do. Continue rinsing. If eye irritation persists: Get medical
advice/attention.
Storage Not applicable

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 SAFETY DATA SHEET

Disposal Not applicable

HMIS CLASSIFICATION Health Hazard 1 Flammability 1

Reactivity 0 Personal Protection E

SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS

CHEMICAL NAME 3-Pyridinecarboxamide

BOTANICAL NAME Not applicable
SYNONYM Nicotinamide; Vitamin B3
CHEMICAL FORMULA C₆H₆N₂O
CAS NUMBER 98-92-0
ALTERNATE CAS NUMBER Not applicable
MOLECULAR WEIGHT 122.1
COMPOSITION CHEMICAL NAME CAS NUMBER EC NUMBER % BY WEIGHT
NIACINAMIDE 98-92-0 202-713-4 100
There are no additional ingredients present which, within the current knowledge of the supplier and in the
concentrations applicable, are classified as health hazards and hence require reporting in this section.
NOTES Chemical family: Pyridine derivative.

SECTION 4: FIRST-AID MEASURES

IN CASE OF EYE CONTACT
IN CASE OF SKIN CONTACT
IF SWALLOWED
IF INHALED
SYMPTOMS AND EFFECTS
Flush with copious amounts of water for 15 minutes, separating eyelids with fingers. If irritation persists seek
medical aid.
Wash with soap & water for 15 minutes. If irritation persists seek medical aid.
Call a physician. Wash out mouth with water. Do not induce vomiting without medical advice.
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a
physician.
Not expected to present a significant hazard under anticipated conditions of normal use.

SECTION 5: FIREFIGHTING MEASURES

SPECIFIC HAZARDS ARISING FROM Not applicable

THE CHEMICAL
FLAMMABLE PROPERTIES
HAZARDOUS COMBUSTION PRODUCTS
SUITABLE & UNSUITABLE
EXTINGUISHING MEDIA
PROTECTIVE EQUIPMENT AND
PRECAUTIONS FOR FIREFIGHTERS
May be combustible at high temperature
Under fire conditions, hazardous fumes will be present.
Small fire: dry chemical, CO₂ or water spray. Large fire: dry chemical, CO₂, alcohol resistant foam or water
spray. Do not get water inside containers.
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

SECTION 6: ACCIDENTAL RELEASE MEASURES

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PERSONAL PRECAUTIONS
METHODS & MATERIAL FOR
CONTAINMENT
CLEANUP PROCEDURE
REFERENCE TO OTHER SECTIONS
PRECAUTIONS FOR SAFE HANDLING
CONDITIONS FOR SAFE STORAGE
STORAGE CONDITIONS
SPECIFIC END USE(S)
SECTION 8: EXPOSURE CONTROLS/ PERSONAL PROTECTION
Chemical Name: NICOTINAMIDE
OSHA PEL
ACGIH TLV
NIOSH
AIHA WEEL
Safe Work Australia HSIS
HSE
GESTIS
N/L = Not Listed
EXPOSURE GUIDELINES
PERSONAL PROTECTIVE EQUIPMENT
Last Revision: 06/2019
SAFETY DATA SHEET
Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate
ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
On land, sweep or shovel into suitable containers. Minimize generation of dust.
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Wear
respirator, chemical safety goggles, rubber boots and heavy rubber gloves. Stop leak if you can do it without
risk. Prevent entry into waterways, sewers, basements or confined areas. Shut off all sources of ignition.
Evacuate the area. If necessary, employ water fog to disperse the vapors. Absorb the matter with compatible
vermiculite or other absorbing material. Place in a suitable container and retain for disposal. Ventilate and clean
the affected area. Do not flush into sewerage system or to drains.
See Section 7 for information on safe handling. See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
SECTION 7: HANDLING AND STORAGE
Do not inhale. Avoid contact with eyes, skin and clothing. Avoid prolonged or repeated exposure. Wash
thoroughly after handling. Store away from incompatible materials, in a well-ventilated area. Eliminate all
sources of ignition. Store in accordance with local regulations. Do not store in unlabeled containers.
Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Use
appropriate containment to avoid environmental contamination.
Store away from incompatible materials, in a well-ventilated area. Eliminate all sources of ignition. Store in
accordance with local regulations. Do not store in unlabeled containers. Containers that have been opened
must be carefully resealed and kept upright to prevent leakage. Use appropriate containment to avoid
environmental contamination.
Store in original container, tightly sealed, protected from direct sunlight and moisture.
Preserve in tight containers.
See Section 1
CAS #: 98-92-0
TWA Ceiling STEL REL IDLH Remarks
N/L N/L - - - -
N/L N/L N/L - - -
N/L N/L N/L N/L N/L -
N/L N/L N/L - - -
N/L N/L N/L - - -
N/L N/L N/L - - -
N/L N/L N/L - - *see below
Consult local authorities for provincial or state exposure limits. Particulates not otherwise regulated, respirable
fraction: 5 mg/m³
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by WHMIS or OSHA's
eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate
gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: Follow WHMIS or OSHA respirator regulations found in 29 CFR 1910.134 or European Standard
EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are
exceeded or if irritation or other symptoms are experienced. Thermal Hazards: For products representing a
thermal hazard, appropriate Personal Protective Equipment should be used.
NIACINAMIDE, USP (Nicotinamide) Page 3 of 8
 SAFETY DATA SHEET

SPECIFIC ENGINEERING CONTROLS Adequate mechanical ventilation. Fumehood, eye wash station, and safety shower.
NOTES GESTIS
Latvia - LV (8 Hr): 1 mg/m³

SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE Solid

DESCRIPTION White crystalline powder. Odorless or practically so.
SOLUBILITY Freely soluble in water and in alcohol; soluble in glycerin.
ODOR Odorless or practically so
FLAMMABILITY May be combustible at high temperature

AUTO-IGNITION 480 °C, 896 °F BOILING POINT 157 °C, 314.6 °F DECOMPOSITION Not available
TEMPERATURE TEMPERATURE

EVAPORATION RATE Not available EXPLOSIVE LIMIT Not available FLASH POINT 182 °C, 359.6 °F
(TOC)

log P -0.38 (20°C) LOWER FLAMMABLE/ Not available MELTING/FREEZING (128-131)°C,

(OCTANOL-WATER) EXPLOSIVE LIMIT(S) POINT (262.4-267.8)°F

ODOR THRESHOLD Not available OXIDIZING PROPERTY Not available pH 6.0 - 7.5 (5%)
(20°C)

RELATIVE DENSITY Not available SPECIFIC GRAVITY 1.400 (25°C) UPPER FLAMMABLE/ Not available
(WATER = 1) EXPLOSIVE LIMIT(S)

VAPOR DENSITY Not available VAPOR PRESSURE 0.0000264 kPa VISCOSITY Not available
(AIR = 1) (25°C)

The physical data presented above are typical values and should not be construed as a specification.

SECTION 10: STABILITY AND REACTIVITY

REACTIVITY Not established

CHEMICAL STABILITY Stable under recommended storage conditions
INCOMPATIBLE MATERIALS Strong oxidizers. Strong acids. Strong bases. Mineral acids. Alkalies.
HAZARDOUS DECOMPOSITION Toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides and other gases may occur
PRODUCTS
HAZARDOUS POLYMERIZATION Will not occur

POSSIBLITY OF HAZARDOUS Not established

REACTION
CONDITIONS TO AVOID Moisture, sunlight and extreme temperatures

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SECTION 11: TOXICOLOGICAL INFORMATION
ACUTE TOXICITY
SKIN CORROSION/IRRITATION
SERIOUS EYE DAMAGE/EYE
IRRITATION
RESPIRATORY SENSITIZATION
SKIN SENSITIZATION
GERM CELL MUTAGENICITY
CARCINOGENICITY
ADDITIONAL CARCINOGENICITY
INFORMATION
REPRODUCTIVE TOXICITY
SPECIFIC TARGET ORGAN TOXICITY -
SINGLE EXPOSURE
SPECIFIC TARGET ORGAN TOXICITY -
REPEATED EXPOSURE
ASPIRATION HAZARDS
SIGNS AND SYMPTOMS OF
EXPOSURE
POTENTIAL HEALTH EFFECTS
SECTION 12: ECOLOGICAL INFORMATION
Last Revision: 06/2019
SAFETY DATA SHEET
Oral: Rat: LD50: (mg/kg): 3500
Dermal: Rabbit LD50: (mg/kg): > 2000
Inhalation: Rat: LC50: (mg/L/4hr): Not available
Based on available data, the classification criteria are not met.
No skin irritation (rabbit, OECD Test Guideline 404).
Moderate eye irritation (rabbit, OECD Test Guideline 405)
Repeated dose toxicity : Irritating to eyes: NOAEL (Oral, rat, 28 d) : 215 mg/kg/day; Subacute toxicity study (28
days); (OECD Test Guideline 407)
Due to lack of data the classification is not possible.
Based on available data, the classification criteria are not met.
Due to lack of data the classification is not possible. Data from germ cell mutagenicity tests were not found.
OSHA NICOTINAMIDE is not listed.
NTP NICOTINAMIDE is not listed.
IARC NICOTINAMIDE is not evaluated.
California This product does not contain any chemicals known to the State of California to cause
Proposition 65 cancer, birth defects, or any other reproductive harm.
Based on available data, the classification criteria are not met.
Based on available data, the classification criteria are not met.
Based on available data, the classification criteria are not met.
Based on available data, the classification criteria are not met.
Due to lack of data the classification is not possible.
Symptoms related to the physical, chemical, and toxicological characteristics
Nausea. Vomiting. Diarrhea. Dizziness. Fainting. Headache. Dry eyes. Dry skin. Increased urination. Thirst.
Jaundice. Joint pain. Abdominal pain. Back pain. Muscle pain. Swelling of feet or lower legs. Fever. Changes in
heart rate. Itching. Tiredness. Weakness.
Delayed and immediate effects of exposure
Liver toxicity.
Cross sensitivity
Persons sensitive to niacin may be sensitive to this material also.
Medical conditions aggravated by exposure
Bleeding disorders. Diabetes mellitus. Liver disease. Jaundice. Gout. Peptic ulcer. Gallbladder disease.
Inhalation May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through skin. May cause skin irritation.
Eyes Causes serious eye irritation.
NIACINAMIDE, USP (Nicotinamide) Page 5 of 8

TOXICITY
PERSISTENCE AND DEGRADABILITY
BIOACCUMULATIVE POTENTIAL
MOBILITY IN SOIL
OTHER ADVERSE EFFECTS
SECTION 13: DISPOSAL CONSIDERATIONS
WASTE DISPOSAL
SECTION 14: TRANSPORT INFORMATION
UN PROPER SHIPPING NAME
UN NUMBER
CLASS
PACKING GROUP
AUSTRALIA
HAZCHEM
EU
TRANSPORT IN BULK ACCORDING TO
ANNEX II OF MARPOL 73/78 AND THE
IBC CODE
ENVIRONMENTAL HAZARDS
SPECIAL SHIPPING INFORMATION
SECTION 15: REGULATORY INFORMATION
UNITED STATES REGULATIONS
Last Revision: 06/2019
SAFETY DATA SHEET
EC50: 48 Hr: Crustacea: (mg/L): Not available
LC50: 96 Hr: Fish: Poecilia reticulata (guppy): (mg/L): >1000
EC50: 72 or 96 Hr: Algae (or other aqua plants): (mg/L): Not available
Readily biodegradable (95% in 28 days)
AEROBIC: Nicotinamide was determined to be readily biodegradable in an aerobic screening test
recommended by the Department of Environment, Standing Committee of Analysts, UK(1).
ANAEROBIC: Nicotinamide was not degraded using an anaerobic spore-forming rod (Clostridia sp.) bacteria
isolated from Potamac River mud(1).
BCF = 3
Low; LogPow: -0.38 (20°C)
Based on the Log Kow and Bioconcentration factor value it is expected to have low potential to concentrate in
fatty tissue of fish and aquatic organisms.
Freely soluble in water: 500g/L (25°C)
Henry's Law Constant = 2.9X10-12 atm-cu m/mole. (Volatilization from moist soil surfaces is not expected to be
an important fate process based upon an estimated Henry's Law constant).
Not available
This product is not intended to be released into the environment
Dispose of in accordance with federal / local laws and regulations. Avoid release into the environment.
Not dangerous good
Not applicable
Not applicable
Not applicable
Not applicable
Not listed
Not available
Not applicable
NIACINAMIDE, USP (Nicotinamide) Page 6 of 8
 SAFETY DATA SHEET

CERCLA SARA (Title III)

Chemical Name EPA 40 CFR Part 355 Right-to-know California
40 CFR 40 CFR
& CAS Appendix A Appendix B Pennsylvania New Jersey Massachusetts Prop 65
Part 302.4 Part 372.65
NICOTINAMIDE 98-92-0 N/L N/L N/L N/L N/L N/L N/L N/L
N/L = Not Listed; X = Listed

AUSTRALIAN REGULATIONS

Therapeutic Goods Code of Practices -

Chemical Name Poisons and Therapeutic
Act Illicit Drug
& CAS Goods Regulation
Precursors
NICOTINAMIDE 98-92-0 N/L Listed as Schedule 4 N/L
N/L = Not Listed

EU REGULATIONS
Chemical Name REACH REACH EC EC EC EC EC
& CAS ANNEX ANNEX 1005/2009 850/2004 1107/2009 649/2012 2012/118
XVII XIV
NICOTINAMIDE 98-92-0 N/L N/L N/L N/L N/L N/L N/L

N/L = Not Listed; X = Listed

Any EU regulation not listed above is not applicable to this product.

SECTION 16: OTHER INFORMATION

REFERENCES Available upon request

ABBREVIATIONS AND ACRONYMS ACGIH - American Conference of Governmental Industrial Hygienists; AIHA WEEL – American Industrial
Hygiene Association Workplace Environment Exposure Levels; CAESAR – Computer Assisted Evaluation of
industrial chemical Substances According to Regulations; CAS – Chemical Abstract Service; CERCLA –
Comprehensive Environmental Response, Compensation, and Liability Act; EC50 – Effective Concentration,
50%; EPA – Environmental Protection Agency; GHS – Global Harmonized System; HMIS – Hazardous
Materials Information System; HSE – Health and Safety Executive; HSIS – Hazardous Substances Information
System; IARC – International Agency for Research on Cancer; IDLH - Immediately Dangerous to Life or Health;
IRFMN – Ready Biodegradability Model; ISS – Instituto Superiore Sanità; LC50 – Lethal Concentration, 50%;
LD50 – Lethal Dose, 50%; MSHA - Mine Safety and Health Administration; NIOSH – National Institute for
Occupational Safety and Health; NTP – National Toxicology Program; OSHA PEL – Occupational Safety &
Health Administration Permissible Exposure Limits; QSAR – Quantitative Structure-activity relationship; REL -
Recommended Exposure Limit; SARA – Superfund Amendments and Reauthorization Act; STEL – Short Term
Exposure Limit; TLV – Threshold Limit Value; TWA – Time Weighted Average; WHMIS – Workplace Hazardous
Materials Information System

LAST REVISION 06/2019

SUPERSEDES 04/2019

For a list of changes to the SDS since the last version, please communicate with MEDISCA at
www.medisca.com

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 SAFETY DATA SHEET

DISCLAIMER This document was created in accordance with OSHA, Safe Work Australia and WHMIS regulations. The above
information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide.
The information in this document is based on the present state of our knowledge and is applicable to the
product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of
the product. MEDISCA® shall not be held liable for any damage resulting from handling or from contact with the
above product. Recipients of the product must take responsibility for observing existing laws and regulations.

SUPPLEMENTARY INFORMATION For all country specific requirements not outlined on this Safety Data Sheet, please request Supplementary
Page to this Safety Data Sheet.

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