LAMPIRAN

1. Perhitungan Data
1.1.1 Perhitungan Rata-rata

Kelompok : CMC -Na 0,5% (kontrol)

Jumlah geliat pada rentang waktu 60 menit
Bobot Volume pemberian Waktu Waktu pemberian 10 15 20 25 30 35 40 40 50 55
No 5-
(g) obat (mL) pemberian obat asam asetat 1% 0-5 - - - - - - - - - -
10
15 20 25 30 35 40 45 50 55 60
1 38 0,95 8,43 9,13 13 10 12 11 7 6 5 6 5 3 4 3
2 40 1 8,25 8,55 4 9 17 17 23 24 20 14 11 10 8 6
3 35 0,875 8 8,3 10 11 15 20 15 18 16 18 17 16 13 13
4 32 0,8 13,2 13,5 12 16 10 14 15 4 10 3 8 0 3 10
5 26 0,65 13,5 14,2 12 15 13 19 17 22 23 28 24 35 34 33
6 26 0,65 13,4 12,1 0 9 10 23 24 22 24 23 10 9 7 8
11, 12, 17, 16, 16, 15, 12, 12, 11, 12,
Rata-rata 8,5 16
67 83 33 83 33 3 5 16 5 16

Kelompok : Aspirin 65 mg/kg

BB
Jumlah geliat pada rentang waktu 60 menit
Bobot Volume pemberian Waktu Waktu pemberian 10 15 20 25 30 35 40 40 50 55
No 5-
(g) obat (mL) pemberian obat asam asetat 1% 0-5 - - - - - - - - - -
10
15 20 25 30 35 40 45 50 55 60
1 36 0,9 8,09 8,39 0 2 5 5 1 1 0 5 2 0 0 2
2 27 0,675 8,21 8,51 0 1 6 8 3 6 8 15 16 2 5 7
3 30 0,75 8,38 9,08 3 1 1 1 2 2 0 1 0 0 0 0
4 28 0,7 10,58 11,28 0 6 0 5 2 0 3 0 1 0 0 0
5 32 0,8 8,19 8,49 0 0 3 7 0 7 1 2 1 1 0 0
6 30 0,75 8,1 8,4 0 1 1 0 1 1 1 2 0 0 0 1
1,8 2,6 4,3 2,8 2,1 4,3 3,3 0,8 1,6
Rata-rata 0,5 1,5 0,5
3 7 3 3 6 3 3 3 7

Kelompok : Asam Mefenamat 65 mg/kg BB

Jumlah geliat pada rentang waktu 60 menit
Bobot Volume pemberian Waktu Waktu pemberian 10 15 20 25 30 35 40 40 50 55
No 5-
(g) obat (mL) pemberian obat asam asetat 1% 0-5 - - - - - - - - - -
10
15 20 25 30 35 40 45 50 55 60
1 36 0,9 8,09 8,39 0 9 22 19 15 15 9 8 11 8 5 5
2 30 0,75 8,31 9,01 10 8 15 7 3 5 8 3 6 6 3 4
3 30 0,7 13,42 14,2 17 16 10 8 7 6 5 6 6 3 1 0
4 32 0,8 13,45 14,16 1 2 3 4 9 8 6 9 9 10 8 4
5 33 0,825 13,17 13,47 0 0 4 16 5 9 5 8 6 4 6 8
6 25 0,625 7,55 8,37 0 0 8 6 5 1 0 2 1 2 1 0
5,8 10, 7,3 7,3
Rata-rata 4,67 10 5,5 6 6,5 5,5 4 3,5
3 33 3 3

Kelompok : Paracetamol 65 mg/kg BB

Jumlah geliat pada rentang waktu 60 menit
Bobot Volume pemberian Waktu Waktu pemberian 10 15 20 25 30 35 40 40 50 55
No 5-
(g) obat (mL) pemberian obat asam asetat 1% 0-5 - - - - - - - - - -
10
15 20 25 30 35 40 45 50 55 60
1 32 0,8 8,23 8,53 13 7 14 11 10 10 11 7 15 10 9 9
2 32 0,8 8,3 9 10 7 3 4 3 2 2 2 1 1 1 1
3 25 0,625 11,06 11,36 0 0 5 4 5 8 6 5 5 4 5 2
4 23 0,575 13,48 14,18 0 3 4 1 1 1 6 3 20 8 12 14
5 28 0,7 13,58 14,28 4 11 10 13 12 10 12 16 15 9 8 13
6 38 0,9 8,11 8,41 1 1 1 5 3 4 4 4 1 5 3 0
Rata-rata 4,66 4,8 6,1 6,3 5,6 5,8 6,8 6,1 9,5 6,1 6,3 6,5
7 3 6 3 7 3 3 6 6 33
 1.1.2 Perhitungan % Proteksi

Jumlah geliat kelp . zat uji

%Proteksi Analgetik = 100 - [ Jumlah geliat kelp. kontrol
x 100 % ]
% Proteksi Aspirin

Waktu Waktu
Perhitungan Perhitungan
(Menit) (Menit)

0,5 2,16
0 -5 100 – ( x 100% ) = 94,11% 30 - 35 100 – ( x 100% ) = 86,77%
8,5 16,33

1,8 3 4,33
5 -10 100 – ( x 100% ) = 84,31% 35 – 40 100 – ( x 100% ) = 71,75%
11,67 15,33

2,67 3,3
10 -15 100 – ( x 100% ) = 79,18% 40 - 45 100 – ( x 100% ) = 73,6%
12,83 12,5

4,3 3 0,5
15 -20 100 – ( x 100% ) = 75% 45 - 50 100 – ( x 100% ) = 95,8%
17,33 12,16

1,5 0,8 3
20 - 25 100 – ( x 100% ) = 91% 50 - 55 100 – ( x 100% ) = 92,78%
16,83 11,5

2,83 1,67
25 - 30 100 – ( x 100% ) = 82,31% 55 - 60 100 – ( x 100% ) = 86,26%
16 12,16

% Proteksi Asam Mefenamat

Waktu
Waktu
Perhitungan (Menit Perhitungan
(Menit)
)
4,6 7 5,5
0 -5 100 – ( x 100% ) = 45,05% 30 - 35 100 – ( x 100% ) = 66,31%
8,5 16,33
5,8 3 6
5 -10 100 – ( x 100% ) = 50,04% 35 – 40 100 – ( x 100% ) = 60,86%
11,67 15,3
10,33 6,5
10 -15 100 – ( x 100% ) = 19,48% 40 - 45 100 – ( x 100% ) = 48%
12,83 12,5
10 5,5
15 -20 100 – ( x 100% ) = 42,29% 45 - 50 100 – ( x 100% ) = 54,76%
17,33 12,16
7 , 33 4
20 - 25 100 – ( x 100% ) = 56,62% 50 - 55 100 – ( x 100% ) = 65,21%
16,83 11,5
 7,33 3,5
25 - 30 100 – ( x 100% ) = 54,18% 55 - 60 100 – ( x 100% ) = 71,21%
16 12,16

%Proteksi Parasetamol

Waktu Waktu
Perhitungan Perhitungan
(Menit) (Menit)

4,67 6,83
0 -5 100 – ( x 100% ) = 43,39% 30 - 35 100 – ( x 100% ) = 58,17%
8 ,2 5 16,33
4,83 5,16
5 -10 100 – ( x 100% ) = 58,61% 35 – 40 100 – ( x 100% ) = 66,34%
11,67 15,3
6,16 9,5
10 -15 100 – ( x 100% ) = 51,98% 40 - 45 100 – ( x 100% ) = 24%
12,83 12,5
6,33 6,16
15 -20 100 – ( x 100% ) = 63,47% 45 - 50 100 – ( x 100% ) = 49,34%
17,33 12,16
5,67 6,33
20 - 25 100 – ( x 100% ) = 66,31% 50 - 55 100 – ( x 100% ) = 44,95%
16,83 11,5
5,83 6,5
25 - 30 100 – ( x 100% ) = 63,56% 55 - 60 100 – ( x 100% ) = 46.54%
16 12,16

1.2.3 Pehitungan %Efektifitas

% Proteksi Zat Uji
%Efektifitas Analgetik = x 100%
%Proteksi pembanding
%Efektifitas Asam Mefenamat

Waktu Waktu
Perhitungan Perhitungan
(Menit) (Menit)

45,85 66,31
0 -5 x 100% = 48,71% 30 - 35 x 100% = 76,42%
94,11 86,77
50,04 60,86
5 -10 x 100% = 59,35% 35 – 40 x 100% = 84,82%
84 , 31 71,75
19,48 48
10 -15 x 100% = 24,60% 40 - 45 x 100% = 65,21%
79,18 7 3 ,6
42,2 9 54,76
15 -20 x 100% = 56,38% 45 - 50 x 100% = 57,16%
75 95,8
 56,62 65,21
20 - 25 x 100% = 62,21% 50 - 55 x 100% = 70,28%
91 92,78
54,18 71, 2 1
25 - 30 x 100% = 65,82% 55 - 60 x 100% = 82,55%
82,31 86,77

%Efektifitas Parasetamol

Waktu Waktu
Perhitungan Perhitungan
(Menit) (Menit)

43,39 58,17
0 -5 x 100% = 46,10% 30 - 35 x 100% = 67%
94,11 86,77
58,61 66,34
5 -10 x 100% = 69,58% 35 – 40 x 100% = 92,45%
84,31 71,75
51,98 24
10 -15 x 100% = 65,64% 40 - 45 x 100% = 32,6%
79,18 73,6
63,47 49,34
15 -20 x 100% = 84,62% 45 - 50 x 100% = 51,5%
75 95,8
66,31 44,95
20 - 25 x 100% = 72,86% 50 - 55 x 100% = 48,44%
91 92,78
66,56 46.54
25 - 30 x 100% = 77,22% 55 - 60 x 100% = 53,95%
82,31 86,26