LEMBAR KERJA PESERTA DIDIK (LKPD)

A. Judul : Enzim
B. WACANA
Enzim adalah biokatalisator organik yang dihasilkan organisme hidup didalam
protoplasma, yang terdiri atas protein atau suatu senyawa yang berkaitan dengan protein.
Enzim mempunyai dua fungsi pokok sebagai berikut:
a. Mempercepat atau memperlambat reaksi kimia
b. Mengatur sejumlah reaksi yang berbeda-beda dalam waktu yang sama.
Enzim tersusun atas dua bagian yaitu apoenzim dan koenzim.
Sifat-sifat enzim sebagai berikut :
a. Bekerja secara spesifik ( satu enzim satu substrat)
b. Bekerja reversibel (bekerja bolak balik)
c. Tidak tahan panas
d. Tidak ikut bereaksi
CARA KERJA ENZIM
Cara kerja enzim ada dua yaitu dengan :
1. model kunci gembok (lock and key)
2. induksi pas (induced fit)
C. Alat dan Bahan
1. Alat tulis
2. Buku Literatur
D. Petunjuk Cara Kerja
1. Bacalah Bahan ajar mengenai enzim dan metabolisme sel.
2. Bacalah dengan cermat petunjuk kerja pada LKPD.
3. Jawablah pertanyaan dalam LKPD
4. Buatlah kesimpulandari hasil diskusi kelompokmu
5. Presentasikanlah hasil diskusi kelompokmu di depan kelas.

1. Enzim terdiri atas komponen protein dan nonprotein. Jelaskan!

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2. Tuliskan sifat-sifat enzim!
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3. Suatu enzim dapat bekerja aktif menghidrolisis suatu substrat apabila ada ikatan
antara substrat dan enzim. Ada dua mekanisme kerja enzim yaitu menurut teori lock
and key dan teori induced fit. Jelaskan kedua teori tersebut, lengkapi dengan gambar!
Gambar 1 Teori Lock and key

Gambar 2 Teori Induced Fit

4. Apa fungsi enzim dalam tubuh manusia?

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5. Dalam melakukan perannya sebagai biokatalisator, kerja enzim dipengaruhi oleh
berbagai faktor. Jelaskan!
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