ABSTRAK

Nabilah, Ghaisani. 2012. Ketepatan diagnosis Fine Needle Aspiration Cytology dibandingkan dengan pemeriksaan Biopsi pada tuberkulosis kelenjar getah bening di Laboratorium Patologi Anatomi Rumah Sakit Umum Dr. Soedono Madiun periode Januari 2010-Juli 2011. Tugas Akhir, Fakultas Kedokteran Universitas Muhammadiyah Malang. Pembimbing: (1) Djoni Djunaedi* (2) Rahmiyah Fadilah**. Latar Belakang: Tuberkulosis merupakan salah satu penyakit infeksi terbanyak di dunia. Tuberkulosis kelenjar getah bening adalah manifestasi tuberkulosis di luar paru yang paling banyak ditemukan. Penyakit ini didiagnosis dengan biopsi atau fine needle aspiration cytology (FNAC). Tujuan: Mengetahui dan menghitung ketepatan diagnosis FNAC dibandingkan dengan pemeriksaan biopsi pada tuberkulosis kelenjar getah bening di laboratorium patologi anatomi Rumah Sakit Umum Dr. Soedono Madiun periode Januari 2010-Juli 2011. Metode: Menggunakan analitik observasional dengan desain studi cross sectional. Populasi adalah penderita tuberkulosis kelenjar getah bening rawat jalan dan inap di RSU dr. Soedono Madiun selama 1,5 tahun (1 Januari 2010-31 Juli 2011) dengan jumlah 41 sampel yang memenuhi kriteria inklusi. Untuk menghitung ketepatan pemeriksaan FNAC dengan biopsi dilakukan uji McNemar. Hasil penelitian: Hasil uji McNemar menunjukkan bahwa tidak terdapat perbedaan antara pemeriksaan FNAC dengan biopsi pada TBC kelenjar getah bening dengan p-value 0,250. Kesimpulan: Tidak terdapat perbedaan antara pemeriksaan FNAC dibandingkan dengan biopsi pada TBC kelenjar getah bening.

Kata kunci: Fine Needle Aspiration Cytology, Biopsi, Tuberkulosis Kelenjar Getah Bening

*Guru Besar Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Muhammadiyah Malang **Staf Pengajar Fakultas Kedokteran Universitas Muhammadiyah Malang

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ABSTRACT

Nabilah, Ghaisani. 2012. The efficacy diagnosis of Fine Needle Aspiration Cytology compared with Biopsy in lymphadenitis tuberculosis at Pathological Anatomy Laboratory Dr. Soedono General Hospital Madiun in the period of January 2010-July 2011. Final Project, Medical Faculty, Muhammadiyah University of Malang. Advisors: (1) Djoni Djunaedi* (2) Rahmiyah Fadilah**. Introduction: Tuberculosis is one of infectious disease in the world. Lymphadenitis Tuberculosis is the most common presentation of extrapulmonary tuberculosis.The diagnosis is established only by fine needle aspiration cytology or surgical biopsy. Objective: To know and calculate the efficacy of diagnosis of fine needle aspiration cytology compared with surgical biopsy in lymphadenitis tuberculosis at Pathological Anatomy Laboratory Dr. Soedono General Hospital Madiun in the period of January 2010-July 2011. Method & Sample: This study was analytical observation with cross sectional study design. The population was the lymphadenitis tuberculosis patients at General Hospital Dr. Soedono Madiun in the period of January 2010-July 2011 with the total sample of 41 which fullfill the inclusion criteria. To calculate the efficacy diagnosis of fine needle aspiration cytology compared with surgical biopsy in lymphadenitis tuberculosis, McNemar test was conducted. Result: Using the McNemar test showed that no significant different was found between the fine needle aspiration cytology and surgical biopsy procedure with the p-value 0,250. Conclusion: No significant different are found between fine needle aspiration cytology and surgical biopsy procedure in lymphadenitis tuberculosis patients.

Keyword: Fine Needle Aspiration Cytology, Biopsy, Lymphadenitis Tuberculosis

*Great Lecturer in Department Internal, Medical Faculty Muhammadiyah University of Malang **Lecturer in Medical Faculty Muhammadiyah University of Malang

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