Isi : 100 Tablet

NEWPROFEN®
Ibuprofen Tablet Kunyah

Komposisi
Tiap tablet mengandung:
Ibuprofen……………………………………………………………………………………………………….. 200 mg
PVP…………………………………………………………………………………………….....………………... 5 %
Mg Stearat………………………..………………………………………………………………...………….... 2 %
Talk….……………………………………………………………………………........………....…………..…… 5 %
Tartrazin………….………………………………………………………………………...…………………….0,6 %
Orange Flavour…………………..……………………………………………………...……………............0,5 %
Sukrosa......................................................................................................................................................ad 400 mg

Farmakologi Obat
Ibuprofen bekerja sebagai antiinflamasi, analgesik, dan antipiretik melalui inhibisi produksi
hormone prostaglandin. Ibuprofen dimetabolisme di dalam hati secara cepat dan
didistribusikan ke seluruh jaringan tubuh. Waktu paruh ibuprofen adalah sekitar 2 jam dan
diekskresikan secara lengkap dalam 24 jam

Indikasi
Untuk meringankan nyeri ringan sampai sedang, nyeri pada sakit gigi, sakit kepala,
meringankan gejala penyakit rematik, sendi, trauma otot dan musculoskeletal
Kontra Indikasi
Penderita dengan ulkus peptikum, hipersensitif terhadap ibuprofen dan Antiinflamasi non-
steroid
Dosis & Aturan pakai
Anak-anak ≥6 bulan sampai ≥12 tahun: 4–10 mg/kgBB per hari, tiap 6–8 jam sekali. Dosis
maksimal adalah 40 mg/kgBB per hari.
Efek samping
Pusing, sakit kepala, dispepsia, diare, mual, muntah.

Interaksi obat
 Peningkatan risiko terjadinya hiperkalemia dan kerusakan ginjal jika digunakan
dengan ciclosporin atau tacrolimus
 Peningkatan kadar ibuprofen yang dapat memicu efek samping jika digunakan
bersama lithium atau methotrexate
Peringatan
Tidak dianjurkan pada pasien dengan perdarahan, ulkus, perforasi pada lambung, gangguan
pernafasan, gangguan fungsi jantung, gangguan fungsi ginjal, gangguan fungsi hati,
hipertensi tidak terkontrol, hiperlipidemia, diabetes melitus, gagal jantung kongestif,
penyakit jantung iskemik, penyakit serebrovaskular, penyakit arteri periferal, dehidrasi,
meningitis aseptik

Simpan dalam wadah tertutup baik

Terlindung dari cahaya
No. BATCH : 1001231
No. REG : DTL2310000163A1
MFG DATE :-
EXP DATE :-
HET :

PT. NewFarma
Kendari - Indonesia
Content : 100 Tablets

NEWPROFEN®
Chewable Ibuprofen Tablets

Composition
Each tablet contains:
Ibuprofen……………………………………………………………………………………………………….. 200 mg
PVP…………………………………………………………………………………………….....………………... 5 %
Mg Stearat………………………..………………………………………………………………...………….... 2 %
Talc….……………………………………………………………………………........………....…………..…… 5 %
Tartrazin………….………………………………………………………………………...…………………….0,6 %
Orange Flavour…………………..……………………………………………………...……………............0,5 %
Sukrosa.....................................................................................................................................................ad 400 mg

Drug Pharmacology
Ibuprofen works as an anti-inflammatory, analgesic and antipyretic by inhibiting the
production of the hormone prostaglandin. Ibuprofen is rapidly metabolized in the liver and
distributed to all body tissues. The half-life of ibuprofen is about 2 hours and is completely
excreted within 24 hours

Indication
To relieve mild to moderate pain, pain in toothaches, headaches, relieve symptoms of
rheumatic diseases, joints, muscle and musculoskeletal trauma
Contraindicate
Patients with peptic ulcer, hypersensitivity to ibuprofen and non-steroidal anti-
inflammatory drugs
Dosage & Rules of Use
Children ≥6 months to ≥12 years: 4–10 mg/kg per day, every 6–8 hours. The maximum dose
is 40 mg/kg per day
Side Effect
Dizziness, headache, dyspepsia, diarrhea, nausea, vomiting.

Drug Interaction
 Increased risk of hyperkalemia and renal damage when used with ciclosporin or
tacrolimus
 Increased levels of ibuprofen which can trigger side effects when used with lithium or
methotrexate
Warning
Not recommended in patients with bleeding, ulcers, perforation of the stomach, respiratory
disorders, impaired cardiac function, impaired renal function, impaired liver function,
uncontrolled hypertension, hyperlipidemia, diabetes mellitus, congestive heart failure,
ischemic heart disease, cerebrovascular disease, arterial disease peripheral, dehydration,
aseptic meningitis
Store in a well closed container
Protected from light
No. BATCH : 1001231
No. REG : DTL2310000163A1
MFG DATE :-
EXP DATE :-
HET :

PT. NewFarma
Kendari - Indonesia