Publikasi Maipa2 (Dian)
Publikasi Maipa2 (Dian)
Publikasi Maipa2 (Dian)
Sumatera Barat
Dian Handayani1*, Maipa Deapati1, Marlina1, Meilan2
1
Abstract
In vitro antimicrobial activity of ten sponge species (Porifera), collected from offshore zone of Painan, West
Sumatera, against isolated strains of bacteria Vibrio cholera were conducted in this study. The extracts of each
sponge were evaluated through the disk diffusion assay. The results showed that 80% (8 from10 extracts) of the
sponge extracts presented activity against Vibrio cholera. The two most active sponges against tested bacteria
were: Petrosia nigrans and Axinella sp.
Keywords :
Pendahuluan
Tabel 1. Hasil uji antibakteri dari beberapa spon laut terhadap Vibrio cholerae dari Batissa Violacea
Lamark (lokan).
Diameter Hambat Ekstrak Metanol spon laut (mm)
No.
Sampel
1%
5%
10 %
20 %
1
Petrosia nigrans
15
22
30
30
2
Halichondria panicea
8
8
8
3
DH 106
11
11
12
4
Halicondria sp
8
11
4
Acanthella sp.
15
15
12
6
Axinella sp
13
23
29
34
7
DH 116
15
18
15
8
Petrosia sp
8
12
12
14
9
Dysidea sp
8
12
20
12
10 Pseudoceratina purpurea
8
13
13
9
11 Kloramfenikol
25
25
25
25
12 Siprofloksazin
28
28
28
28
13 DMSO
Kesimpulan
Dari 11 gram ekstrak total metanol spon laut
Acanthodendrilla sp didapatkan suatu senyawa
berupa lempengan berbentuk kubus, tidak berwarna
sebanyak 60 mg, dimana kristal ini terurai pada
suhu 255oC.
Daftar Pustaka
Faulkner, D. J., Sponges, Marine Natural Products,
Serpps Institution, University of Oceanografi,
University of California, San Diego, 11, 1993,
231-247.
Stachowitsch, M, The Invertebrates, An Ilusctated
Glosary, Department of Marine Biology
Institute of zoologi, Vienna, Austria, 1992, 1318.
Jasin, M, Zoologi Invertabrata Untuk Perguruan
Tinggi, cetakan keempat, Penerbit Sinar Jaya,
Surabaya, 1992, 89-102.
Fusetani N, Drug from The Sea, Karger, Basel,
2000: 1-5.
Wright, A. E., Medicines from The Deep Sea :
Discoveries to Date. Available at :
http://www.oceanexplorer.noaa.gov/exploration
s/03bio/background/medicines/medicines.html.
Accessed July 11, 2005.