Nama: ____________________________, Kelas: XII.IP__ ___, No.

Absen: ___,
Hari,tgl: _____________________________

TUGAS KD 4.8-MUTASI GEN

SMA MUHAMMADIYAH WONOSOBO

Menerapkan Gagasan Besar

Pada manusia, suatu gen yang mengkodekan bagi satu rantai polipeptida dari protein hemoglobin
darah terletak pada kromosom nomor 11. Mutasi substitusi yang terjadi pada gen tersebut
menyebabkan asam amino valin dimasukkan ke dalam hemoglobin ditempat dimana secara normal
asam amino asam glutamat berada. Sebagai hasilnya adalah penyakit siklemia (anemia bulan sabit).
Terangkan bagaimana perubahan sebuah basa nitrogen di dalam DNA dapat mengakibatkan suatu
gangguan/ penyakit yang serius?
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Selamat Belajar

KELAS
NAMA NILAI
NO. ABSEN

12. IP__ __/___

Diterjemahkan dan diadaptasi dari Miller & Levine, 1992. Biology, Study Workbook A, 1
Pearson Education, Inc., or its affiliates. Page 204 oleh Rahayu Fitriningrum