DAFTAR ISI

Halaman
HALAMAN JUDUL........................................................................................ i

HALAMAN PENGESAHAN.......................................................................... ii

HALAMAN PERSETUJUAN......................................................................... iii

HALAMAN PERSEMBAHAN....................................................................... iv

HALAMAN PERNYATAAN.......................................................................... v

KATA PENGANTAR...................................................................................... vi

DAFTAR ISI.................................................................................................... viii

BAB I PENDAHULUAN

1.1 Latar Belakang .............................................................................. 1

1.2 Rumusan masalah ......................................................................... 4

1.3 Tujuan Penelitian........................................................................... 4

1.4 Manfaat Penelitian......................................................................... 4

1.5 Hipotesa .................................................................................. 5

BAB II TINJAUAN PUSTAKA

2.1 Virus .............................................................................................. 6

2.1.1 Definisi............................................................................... 6

2.1.2 Infeksi Virus...................................................................... 6

2.2 COVID-19 .....................................................................................

2.2.1 Definisi............................................................................... 8

2.2.2 Epidemiologi ..................................................................... 8

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 2.2.3 Etiologi............................................................................... 9

2.2.4 Patogenesis......................................................................... 11

2.2.5 Penularan........................................................................... 13

2.2.6 Manifestasi Klinis.............................................................. 14

2.2.7 Diagnosis........................................................................... 15

2.2.8 Komorbid Covid-19 .......................................................... 15

2.3 Tatalaksana Covid-19.................................................................... 19

2.3.1 Protokol tatalaksana pasien tanpa gejala (OTG)................ 19

2.3.2 Protokol tatalaksana pasien gejala ringan.......................... 21

2.3.3 Protokol tatalaksana pasien gejala sedang......................... 22

2.3.4 Protokol tatalaksana pasien gejala berat............................ 23

2.4 Antivirus Covid-19......................................................................... 25

2.4.1 Favipiravir....................................................................... 25

2.4.2 Remdesivir....................................................................... 26

2.4.3 Oseltamivir...................................................................... 28

2.5 Metode ATC/DDD...................................................................... 29

2.5.1 Metode ATC.................................................................... 30

2.5.2 Metode DDD................................................................... 31

BAB III METODE PENELITIAN

3.1 Waktu dan Tempat Penelitian ....................................................... 33

3.2 Rancangan Penelitian .................................................................... 33

3.3 Populasi dan Sampel...................................................................... 33

3.3.1 Populasi.............................................................................. 33

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 3.3.2 Sampel................................................................................ 33

3.4 Instrumen Penelitian...................................................................... 34

3.5 Definisi Operasional...................................................................... 35

3.6 Prosedur Penelitian........................................................................ 35

3.7 Analisis Data.................................................................................. 37

BAB IV HASIL DAN PEMBAHASAN

4.1 Hasil ............................................................................................. 38

4.2 Pembahasan .................................................................................. 43

BAB V KESIMPULAN

5.1 Kesimpulan ................................................................................... 51

5.2 Saran ............................................................................................. 51

DAFTAR PUSTAKA .................................................................................. 52

LAMPIRAN .................................................................................. 56