DAFTAR ISI

Halaman
DAFTAR TABEL................................................................................................. iv
DAFTAR GAMBAR..............................................................................................v
BAB 1 PENDAHULUAN...................................................................................... 1
1.1 Latar Belakang.........................................................................................1
1.2 Rumusan Masalah....................................................................................2
1.3 Hipotesis...................................................................................................2
1.4 Tujuan Penelitian..................................................................................... 2
1.5 Manfaat Penelitian................................................................................... 3

BAB 2 TINJAUAN PUSTAKA.............................................................................4

2.1 Sepsis....................................................................................................... 4
2.1.1 Definisi.................................................................................................4
2.1.2 Etiologi.................................................................................................4
2.1.3 Patofisiologi......................................................................................... 4
2.1.4 Gejala Klinik........................................................................................6
2.1.5 Diagnosis Klinis...................................................................................6
2.1.6 Tata Laksana......................................................................................10
2.2 Mortalitas...............................................................................................13
2.3 Faktor Risiko Mortalitas pada Sepsis.....................................................13
2.3.1 Mean Arterial Pressure (MAP)......................................................13
2.4 Intensive Care Unit (ICU)......................................................................14
2.4.1 Definisi...............................................................................................14
2.4.2 Indikasi Masuk dan Keluar ICU........................................................ 14
2.4.3 Pasien Sepsis di ICU..........................................................................15

BAB 3 METODE PENELITIAN........................................................................16

3.1 Desain Penelitian....................................................................................16
3.2 Waktu dan Tempat Penelitian................................................................16
3.3 Populasi dan Sampel Penelitian.............................................................16
3.3.1 Populasi Penelitian................................................................................16
3.3.2 Sampel Penelitian..................................................................................16
3.4 Kriteria Inklusi dan Eksklusi..................................................................17
3.4.1 Kriteria Inklusi...................................................................................... 17
3.4.2 Kriteria Eksklusi................................................................................... 17

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 3.5 Identifikasi Variabel...............................................................................17
3.5.1 Variabel Bebas..................................................................................17
3.5.2 Variabel Terikat................................................................................ 17
3.6 Definisi Operasional.............................................................................. 18
3.7 Instrumen dan Cara Penelitian............................................................... 18
3.7.1 Instrumen Penelitian............................................................................. 18
3.7.2 Cara Pengambilan Data.........................................................................18
3.8 Alur Penelitian....................................................................................... 19
3.9 Pengolahan dan Analisis Data................................................................20
3.9.1 Analisis Univariat............................................................................. 20
3.9.2 Analisis Bivariat................................................................................20
3.10 Etika Penelitian...................................................................................... 21
DAFTAR PUSTAKA...........................................................................................22

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 DAFTAR TABEL

Halaman
Tabel 1. Skor Sequential Organ Failure Assessment (SOFA)...............................9
Tabel 2. Definisi Operasional Variabel..................................................................18
 DAFTAR GAMBAR

Halaman
Gambar 1. Rantai koagulasi...................................................................................6
Gambar 2. Algoritma Skrining untuk Dugaan Sepsis dan Syok Septik.................8
Gambar 3. Kurva Receiver Operating Characteristic (ROC)...............................10
Gambar 4. Rumus Mean Arterial Pressure (MAP)................................................14
Gambar 7. Alur Penelitian.....................................................................................19