APPRAISAL
(TELAAH KRITIS)
PENELITIAN
KEDOKTERAN
TELAAH KRITIS = CRITICAL APPRAISAL
Menambah pemahaman
Mengikuti perkembangan
Melakukan penelitian
LANGKAH AWAL TELAAH KRITIS
PENILAIAN JUDUL,
ABSTRAK DAN RUJUKAN
PEMBAHASAN
TELAAH KRITIS
Penilaian struktur & kelengkapan
makalah
Judul
Nama pengarang & institusinya
Abstrak
Pendahuluan
Metodologi penelitian
Hasil
Diskusi/pembahasan
Ucapan terima kasih
Daftar rujukan
PENILAIAN TERHADAP JUDUL
Informasi menyeluruh/ringkas
Latar belakang/tujuan
Rancangan penelitian
Metodologi
Hasil
Kesimpulan
Saran
Kurang dari 250 kata
RUJUKAN
Rujukan terbaru
(Terutama jurnal hasil
penelitian)
Penulisan yang tepat
CHECK LIST UMUM STRUKTUR DAN
ISI MAKALAH
CHECK LIST
YA
TIDAK
TIDAK RELEVAN
PENDAHULUAN
2. Prognosis
3. Therapy/Treatment
4. Risk/Harm
Others:
Systematic Review and Meta-analysis
Clinical Guidelines
1. VALIDITY :
VALID (CLOSENESS TO THE TRUTH) IN THE
METHODOLOGY SECTION
2. IMPORTANCE :
IMPORTANT (USEFULNESS) IN THE RESULTS SECTION
3. APPLICABILITY :
APPLICABLE (CAN BE APPLIED IN CLINICAL PRACTICE)
IN THE DISCUSSION SECTION
DIAGNOSIS WORKSHEET
Citation:
Totals
Target disorder
Present Absent
Diagnostic Positive a b a+b
test result
Negative c d c+d
Totals a+c b+d a+b+c+d
SnNout
SpPin
Additional notes:
Apakah ada perbandingan, independen buta dengan referensi ("emas")
standar diagnosis?
Apakah tes diagnostik dievaluasi dalam spektrum yang sesuai pasien (seperti di
yang akan digunakan dalam praktek)?
Apakah standar referensi diterapkan tanpa hasil uji diagnostik?
Apakah tes (atau kelompok tes) divalidasi dalam kelompok, kedua pasien
independen?
Apakah tes diagnostik yang tersedia, terjangkau, akurat, dan tepat dalam
pengaturan Anda?
Dapatkah Anda menghasilkan perkiraan klinis yang masuk akal dari
probabilitas pre-test pasien Anda (dari pengalaman pribadi, statistik
prevalensi, database praktek, atau studi utama)?
Apakah pasien penelitian serupa dengan Anda sendiri?
Apakah tidak mungkin bahwa kemungkinan penyakit atau
probabilitas telah berubah sejak bukti itu dikumpulkan?
Apakah post-test sehingga mempengaruhi probabilitas manajemen
Anda dan membantu pasien Anda?
Mungkinkah menggerakkan Anda melintasi ambang tes- perawatan?
Apakah pasien Anda bersedia menjadi mitra dalam menjalankan test?
Apakah konsekuensi dari uji membantu pasien Anda?
Example : an article of diagnostic test, entitle :
Bedside Diagnosis of
Influenzavirus Infections
in Hospitalized Children
Katherine A. Poehling, et al
American Academy of Pediatrics
Background:
Influenzavirus has a significant impact on the pediatric
population, with school-aged children having the highest
infection rates.
For preventing nosocomial influenza infections and to
facilitate prompt antiviral therapy, an accessible, rapid
diagnostic method for influenzavirus is needed.
Objective:
To compare the performance of a rapid diagnostic test
(QuickVue Influenza Test; Quidel Corp, San Diego, CA)
completed at the bedside of hospitalized children to viral
culture and/or polymerase chain reaction (PCR) for
influenzavirus.
Method:
Study population:
1) younger than 19 years and hospitalized with respiratory
symptoms or 2) younger than 3 years and hospitalized with
fever.
Sampel: 1) a primary admission diagnosis of an acute
respiratory illness characterized by rhinorrhea, sore throat,
cough, shortness of breath, or apnea or 2) a primary
admission diagnosis consistent with a febrile illness and a
temperature of 100.4F.
Broad inclusion criteria were chosen such that all children
who were hospitalized with symptoms potentially related to
influenza infections were eligible.
Sample in
this study
Study design:
prospective, cross sectional study from each child, 2 nasal
swabs of the turbinates were obtained1 for influenzavirus
culture and PCR and the other for the rapid diagnostic test.
The rapid test results were compared with that of culture and
PCR for influenzavirus.
SAMPLE CALCULATIONS
Totals
Target disorder
Present Absent
Diagnostic Positive a b a+b
test result
Negative c d c+d
Totals a+c b+d a+b+c+d
+ -
+ 14 5
- 5 209
Culture or PCR Totals
Present Absent
Quick Vue Positive 14 5 19
Influenza
Negative 5 209 214
test
Totals 19 214 233