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Bone Graft

drg. Ericka Winda Setiawaty


Periodontics Resident FKG UGM
GRAFT

• Graft adalah suatu bagian jaringan yang diambil dari satu tempat dan
ditransplantasikan ke tempat lain, baik pada individu yang sama maupun yang
berlainan.
• Tujuan : memperbaiki cacat yang disebabkan oleh penyakit, kecelakaan, atau
anomali pertumbuhan dan perkembangan

(Horowitz, et al., 2014)


BONE GRAFT

• Prosedur bedah yang menggantikan tulang yang hilang dengan bahan dari
tubuh pasien sendiri, pengganti buatan, sintetis, atau alami
• Kerusakan Tulang Periodontal

(Horowitz, et al., 2014)


TUJUAN BONE GRAFTING

Mengurangi kedalaman Peningkatan


poket periodontal perlekatan secara
klinis
A B
Pengisian tulang di
daerah defek
C D Regenerasi tulang
baru, semen dan
ligamen periodontal
FUNGSI BONE GRAFTING
Mendorong terjadinya osteogenesis
(pembentukan tulang)

Memberi dukungan mekanis


pada kerangka resipien
(mechanical support)
JENIS BONE GRAFT ALAMI

AUTOGRAFT

ALLOGRAFT

XENOGRAFT
JENIS GRAFT SUBSTITUSI
MATERIAL

Subsitusi graft tulang dengan dasar allograft


Subsitusi graft tulang dengan dasar faktor  faktor pertumbuhan alami dan
recombinant
Subsitusi graft tulang dengan dasar sel  Stemcell
Subsitusi graft tulang dengan dasar keramik: kalsium fosfat, kalsium sulfat, dan
biolgas (Haurencin et al. (2006)
Extraction Site Preservation Using an
In-Situ Hardening Alloplastic Bone
Graft Subtitute

CASE REPORT

drg. Ericka Winda Setiawaty


Periodontics Resident FKG UGM
CASE REPORT
COMPENDIUM

(Lewentis, et al., 2014)


INTRODUCTION
STUDI KLINIS &
EKSPERIMENTAL
Pencabutan gigi Immediate socket grafting

Mempertahankan Dimensi, kontur,


• Resorpsi tulang dan arsitektur kerangka alveolar dan
• Atrofi ridge tulang alveolar residu ridge.
• Mempersulit penempatan
implant.
Bone graft biologis maupun sintetis 
Socket Preservation & Regeneration for
Immediate socket grafting Implant Placement
INTRODUCTION

Fig 1. initial clinical


situation. Mandibular
right lateral incisor
was fractured.
INTRODUCTION

Fig 2. atraumatic extraction


without flap raising. The
socket was grafted with the
in-situ hardening alloplastic
material. No primary closure
was necessary. vertical
cross-mattress sutures were
placed to stabilize the
adjacent papillae.
INTRODUCTION
MATERIAL BONE
GRAFT
• Bervariasi komposisi
• Karakteristik mekanik
• Mekanisme fungsi biologis:
resorpsi pembentukan tulang baru

Alloplasts osteokonduktif sintetis


• Biocompatible
• Non-iritatif
• Ketersediaan mudah didapat

Alloplastic bone substitutes  calcium


phosphate ceramics
CASE
REPORT
CASE REPORT
USIA PENCABUTAN
65 • Anestesi lokal
GIGI
• Atraumatic extraction with periotom 
GENDER No Flap
• Tulang Buccal utuh
Male
Bukan perokok
Tidak ada kontra indikasi POST EXO
• Debridement
implant 42
• Irigasi NaCl steril
• In-Situ Hardening Alloplastic Bone Graft
Subtitute

BONE GRAFT
• In-Situ Hardening Alloplastic Bone Graft
Subtitute
• Butiran β-TCp, dilapisi dengan pLGA
• dicampur di jarum suntik dengan
larutan BioLinker
CASE REPORT
GRAFT GRANULES
• Graft granules  kontak darah/saliva  menempel
--> sticky, easy to handle, mudah dibentuk, mudah
mengeras
• Kasa basah untuk memadatkan 
• Mempercepat proses hard, oseokonduktif, porous
scaffold  host osseus regeneration

PROVISIONAL BRIDGE
• Soket terbuka  Secondary healing
• Penempatan provisional bridge

PENYEMBUHAN POST
• Biomekanik grafting material 
GRAFTING
proliferasi epitel bertahap
• Follow up 4 bulan:
- ditutupi epitel keratin baru
- volume & bentuk ridge adekuat
• Tulang baru, butir tertanam,
kontinuitas jaringan
CASE REPORT

Fig 3. the biomechanical


stability of the graft, provided
by the Plga coating of the β-
tcP granules, permitted
the gradual proliferation of
newly formed soft tissues
over the grafted
site. clinical view 4 days
postoperatively.
CASE REPORT

Fig 4. clinical view 2 weeks


postoperatively.
CASE REPORT

Fig 5. clinical situation after 4


months.
CASE REPORT

Fig 6. re-entry at 4 months.


the site was filled with newly
formed bone.
CASE REPORT

Fig 7. implant
placement; good initial
stability was achieved.
CASE REPORT

Fig 8. provisional restoration


CASE REPORT

Fig 9. final restoration


after 3 months showing
successful esthetic outcome
CASE REPORT

Fig 10. radiographic examination:a. initial situation; b. immediately after socket


grafting; c.bone modeling after 4 months; d. implant placement; e. peri-implant
bone remodeling after 3 months of non-occlusal loading. the maturation of
the surrounding bone can already be radiologically observed.
DISCUSSION
DISCUSSION

• Minimal invasive • Patients generally experience more • β-TCp as a resorbable socket


• Flapless discomfort grafting material
• No membrane use to cover • The mucogingival junction is • Peri-implan bone  adaptasi
the grafted significantly more coronally displaced, sesuai hukum Wolff
• Bio mekanis material  • Esthetic problems
stabilitas mekanik • Negatively influence peri-implant soft-
• Heal by secondary invation tissue health and long-term stability.

FLAPLESS FLAP GRAFTING


MATERIAL
CONCLUSION

In-situ hardening alloplastic Hard- and soft-tissue


bone grafting substitute was preservation and
used in a minimally invasive, regeneration have been
successful, and predictable utilized in achieving an
way for socket preservation A B optimal soft-tissue profile

The in-situ hardening property


of this material may enable C D Both esthetically and
clinicians to utilize a flapless functionally allowing for
procedure without primary improved long-term
wound implant stability.
THANKS
Do you have any questions?

erickawinda@yahoo.co.id
+6282243361340

drg. Ericka Winda Setiawaty


Periodontics Resident FKG UGM

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