CREAM AND

LOTION

DIAH MIFTAHUL AINI, M.SI

28-06-2022
CAPAIAN PEMBELAJARAN
 Mahasiswa mampu menjelaskan analisis cream dan lotion

Setelah mengikuti perkuliahan mahasiswa diharapkan :

1. Menjelaskan bagaimana teknik preparasi analisis creams dan lotion
2. Menjelaskan tahapan dan tujuan analisis creams, dan lotion
3. Menjelaskan metode yang sesuai dengan tujuan analisis
Cream

Lotion
PERBEDAAN CREAM DAN LOTION

 Lotion terasa ringan dan tidak terlalu mengunci hidrasi seperti krim. Karena formulanya yang ringan, lotion dengan
mudah diserap oleh kulit.
 Cream memiliki konsistensi yang lebih kental dibandingkan dengan lotion, dan memiliki sedikit air. cream memiliki
persentase 50% : 50% = air : minyak. Jika dibandingkan lotion, cream lebih menghidrasi. Untuk kulit, cream lebih baik
digunakan untuk kulit kering dan sensitif, guna memperkuat lapisan pelindung kulit.
MATERI PERKULIAHAN

Pengertian Formulasi Analisis sediaan Tugas

cream dan cream dan cream dan
lotion lotion lotion
CREAM

 Krim adalah obat topikal umum yang mengandung rasio air dan minyak yang sama. krim memiliki tekstur
ringan dan cepat diserap oleh kulit. Krim larut dalam air dan sebagian besar digunakan untuk keperluan
kosmetik. krim juga dapat digunakan untuk mengobati alergi, ruam atau masalah kulit lainnya.
FORMULASI SEDIAAN CREAM
ANALISIS SEDIAAN CREAM

1. Organoleptic Characteristics
The formulated creams were observed for physical appearance, color, texture, phase separation, homogeneity and odor. A small
amount of cream was pressed between the thumb and index finger to check for the consistency and presence of coarse particles. In
addition, the stiffness, grittiness and greasiness of the creams upon application were evaluated
2. Determination of Type of Cream (Dilution Test)
The creams were diluted with water. Oil in water (o/w) type cream shows good miscibility with water, whereas water in oil (w/o)
type cream shows poor miscibility with water.
3. Washability
A total of 0.1 g of the cream was applied to the skin and washed under running tap water with minimal force. Good washability of
the cream is demonstrated when the applied cream is easily removed from the area of application, leaving a non-greasy skin surface
ANALISIS SEDIAAN CREAM

4. pH Determination
The pH meter was calibrated with pH 4, 7 and 10 standard buffers before use. A total of 10% w/v of the cream suspension
was prepared for pH measurement at room temperature (25 ◦C). The pH measurement was repeated in triplicate to obtain the
average pH ± SD of the cream suspension. pH was measured initially and monthly for three months .
5. Centrifugation Test
The centrifugation test was conducted at zero, one, two and three months of storage at 40 ± 2 ◦C and 75 ± 5% RH. A total of
2 g of the cream was centrifuged at 25 ◦C and 5000× g rpm for two runs of 10 min. The stability, phase separation and
appearance of the cream after centrifugation were observed after each run.
LOTION

 Lotion adalah sediaan cair yang dimaksudkan untuk aplikasi eksternal tanpa gesekan. Lotion diterapkan langsung ke
kulit dengan bantuan beberapa bahan penyerap, seperti, kapas atau kain kasa yang direndam di dalamnya.
FORMULASI SEDIAAN LOTION
Formulasi sediaan lotion menthol

Procedure:
1. The required amount of each ingredient should be weighed/measured accurately.
2. Take 0.2ml of menthol and mix in 9ml alcohol with simultaneously addition of 0.5gm of
tragacanth.
3. Add measured amount of glycerine and make volume upto 100ml with water.
4. Mix the contents thoroughly until a smooth mixture results.
Formulasi sediaan lotion aloe vera

Procedure:
1. Take grated bees wax, add coconut oil and shea butter to it and keep on water bath for melting of all ingredients in
double boiler.
2. Take a blender pour a above melted ingredients
3. Refrigerate for 15 mins
4. Again blend and add aloe vera gel
5. Again blend and in last add peppermint oil
6. Blend again and keep the lotion in air tight container
ANALISIS SEDIAAN LOTION
 1. Homogeneity

The formulation were tested for homogeneity by visual appearance and by touch.
 2. Appearance

The appearance of the lotion

 3. After feel

Emolliency, slipperiness and amount of residue left after the application of fixed amount of lotion was checked.
 4. Acid Value

Take 10gm of substance dissolve in accurately weighed in 50ml mixture of equal volume of alcohol and solvent ether. The flask was
connected reflux condenser and slowly heated, until sample was dissolved completely. To this 1ml of phenolphthalein added and
titrated with 0.1N NaOH, until faintly pink colour appeares after shaking for 30sec.
Acid Value=n x 5.61/w
n= number of ml of NaOH required
w= weight of substance
5. pH measurement

The pH meter was calibrated using standard buffer solution. About 0.5gm of clotion was weighed and dissolved in 50ml of distilled
water and its pH was measured using digital pH meter.

6. Irritancy test

Mark an area (1 sq. cm) on the left hand dorsal surface. The lotion was applied to the specified area and time was noted. Irritancy,
erythema, edema, was checked if any for regular intervals upto 24hrs and reported.

7. Viscosity

Viscosity of the formulation was determined was brookfield or ostwald viscometer at 100 RPM, using spindle no. 7 at temp 25oC.
The determinations were carried out in triplicate and the average of three reading was recorded. for 5 min, and the viscosity
measured a rotating speed of 50 rpm.
TUGAS

 Diskusikan bagaimana cara memilih cream dan lotion yang baik untuk kulit
REFERENSI

 Tan, P.L.; Rajagopal, M.; Chinnappan, S.; Selvaraja, M.; Leong, M.Y.; Tan, L.F.; Yap, V.L. Formulation and
Physicochemical Evaluation of Green Cosmeceutical Herbal Face Cream Containing Standardized Mangosteen Peel
Extract. Cosmetics 2022, 9, 46. https://doi.org/ 10.3390/cosmetics9030046