Stool Color Card Screening for Early Detection of Biliary Atresia and

Long-Term Native Liver Survival: A 19-Year Cohort Study in Japan

Journal Reading

Perceptor:
dr. M Taufik Perwira W, Sp.A

Kelompok 7 :
Delisa Mutiara Nabila 22180122082
Kevin Jeremia Purba 22180121823
Khairunisa Salsabila 22180121554
Naufal Rivo Aditya 22180121805
Rr. Astri Nur Azizah 2218012129

KEPANITERAAN KLINIK ILMU KESEHATAN ANAK

RSUD DR. H. ABDUL MOELOEK PROVINSI LAMPUNG
FAKULTAS KEDOKTERAN UNIVERSITAS LAMPUNG
2023
 Outline

01 02 03
Abstrak Pendahuluan Metode

04 05 06
Hasil Diskusi Critical appraisal
Abstrak
Tujuan
Mengevaluasi
sensitivitas &
spesifisitas Stool Color
Card (SCC) untuk
skrining massal atresia Desain penelitian
bilier yang dilakukan 1994-2011: SCC didistribusikan ke
selama 19 tahun semua ibu hamil di Tochigi
Jepang, dikembalikan setelah diisi
Menyelidiki usia rata- saat pemeriksaan pada 1 bulan
rata saat melakukan paska melahirkan
prosedur Kasai dan • Semua kasus yang dicurigai
probabilitas jangka atresia bilier dirujuk. 
panjang kelangsungan • Diagnosis ditegakkan dengan
hidup hepar bawaan. laparotomi atau kolangiografi
operatif sebelum prosedur Kasai
• Pasien atresia bilier di-follow up
dari tanggal prosedur Kasai
sampai transplantasi hati,
kematian, atau 31 Oktober 2013
 Tujuan
• 313.230 bayi diskrining
• 34 pasien terdiagnosis atresia bilier
• Sensitivitas dan spesifitas skrining
SCC pada pemeriksaan 1 bulan
adalah 76,5% dan 99,9%
• Usia rata-rata pada saat prosedur
Kasai adalah 59,7 hari
• Probabilitas kelangsungan hidup
hepar bawaan pada 5, 10 dan 15
tahun adalah 87,6%, 76,9%, dan
48,5%
Desain penelitian
Sensitivitas dan spesifitas SCC telah dibuktikan
oleh Studi Kohort 19 tahun ini. Peneliti
menemukan bahwa waktu prosedur Kasai dan
probabilitas kelangsungan hudup hepar
bawaan jangka panjang yang meningkat
menunjukkan efek menguntungkan dari
skrining SCC.
 Pendahuluan
Atresia bilier adalah kasus penyakit hati
yang terbanyak menyebabkan kematian
 Insidensi

0,5 dalam 10.000

0,7 dalam di Prancis
10.000 di US

0,6 dalam 1,0 dalam

10.000 di UK 10.000 di
Jepang
 Prosedur Kasai

• Sebagai pengobatan lini pertama untuk semua jenis atresia bilier 

• Sebelum 60 hari, dilakukan lebih awal → dapat meningkatkan
kelangsungan hidup jangka panjang hepar bawaan dan mengurangi
kemungkinan transplantasi hati 

66,1% di Jepang 
Transplantasi hati yang dilakukan penerima di bawah usia 18 tahun
disebabkan atresia bilier → perlunya skrining atresia bilier
 1994 2002
Konsep SCC untuk skrining SCC untuk skrining masal diadopsi
massal diperkenalkan dan digunakan di Taiwan →
pertama kali kepada menghasilkan rujukan awal pasien
penduduk lokal di Prefektur dengan atresia bilier
Tochigi oleh Matsui dan
Dodoriki → menghasilkan
prosedur Kasai dini (usia <60
hari) → sejak saat itu SCC
didistribusikan hingga Maret
2011
Introduction
This can be the part of the presentation where
you introduce your healthcare center
 01
Our center
You can describe the topic of the
section here
01
Our center
You can describe the topic of the
section here
Mission
Jupiter is a gas giant
and the biggest planet
in the Solar System

Vision
Venus is the second
planet from the Sun.
It’s really hot there
 Key numbers

20,000
This is the number of total
50,000
This is the number of patients
visitors we had last month we had last month

5,000
This is the number of
recoveries made so far
 333,000
The Sun mass compared to Earth’s

9h 55m 23s
Jupiter’s rotation period

386,000 km
Distance between Earth and the Moon
Tujuan penelitian
Untuk menentukan sensitivitas dan
spesifisitas skrining SCC selama periode
19 tahun serta pengaruhnya terhadap
waktu
 Our statistics
Mars
30% Despite being red,
Mars is a cold place

Saturn
60% Saturn is composed
mostly of hydrogen

Venus 2005 2010 2015 2020

10% Venus has a
beautiful name
If you want to modify this graph, click on it, follow the
link, change the data and replace it
 Our statistics

Venus
Venus is the second
planet from the Sun.
It’s really hot

Jupiter
Jupiter is the biggest
planet in the entire
2017 2018 2019 2020 2021 Solar System

Follow the link in the graph to modify its data and then paste the new one here. For more info,
click here
 Our numbers

Budget
80% 50% 70%

Sales People Market

Neptune is far Mars is a really Jupiter is the
away from us cold place biggest planet

$28.87 30 days 45 labs 77 units

Avg. price per unit Avg. days on market Retailers Remaining inventory
 Brief story
Mercury is the closest planet to the Sun and the
smallest one in the Solar System
Brief story
Mercury is the closest planet to the Sun
and the smallest one in the Solar
System
745,145
Big numbers catch your audience’s attention
 13,11
9
Big numbers catch your
audience’s attention
 Milestones reached
Mars Saturn
Despite being red, Mars It’s composed mostly of
is a cold place, not hot hydrogen and helium

2007 2010 2014 2018

Mercury Venus
Mercury is the closest It has a beautiful name,
planet to the Sun but it’s terribly hot
 Milestone reached

Mars Earth
Mars is a cold Earth is where
place, not hot we all live

Saturn is the Venus has a

ringed planet beautiful name

Saturn Venus
Our process

Do you know what helps you make

your point clear? Lists like this one:

● They’re simple
● You can organize your ideas in
a very clear way
● You’ll never forget to buy milk!

And the most important thing: the

audience won’t miss the point of
your presentation
 Patient care
Mercury is the closest planet to the Sun and the
smallest one in the Solar System
 Patient care

Venus has a beautiful name and is the second

planet from the Sun. It’s hotter than Mercury, and
its atmosphere is extremely poisonous
 Our process

01 Venus Mars 03
Venus has a Mars is a cold
beautiful name place, not hot

02 Saturn Jupiter 04
Saturn is a gas Jupiter is the
giant with rings biggest planet
 Venus
Venus is the second
planet from the Sun

Saturn
Saturn is a gas giant and
Our has several rings

process Mars
Despite being red, Mars
is actually a cold place

Jupiter
It’s the biggest planet in
the Solar System
 Services

Mercury Venus Mars

Mercury is the Venus has a Despite being red,
smallest planet beautiful name Mars is a cold place

Jupiter Saturn Neptune

It’s the biggest Saturn is a gas giant Neptune is far away
planet of them all with several rings from Earth
 Services
Mercury Jupiter
Mercury is the closest It’s the biggest planet
planet to the Sun in the Solar System

Mars
Despite being red,
Mars is a cold place

Saturn Neptune
Saturn is a gas giant It’s the farthest planet
and it has rings from the Sun
 Areas we cover

30% Mercury Mars 20%

Mercury is the Despite being red,
smallest planet Mars is cold

10% Jupiter Neptune 40%

Jupiter is the Neptune is far
biggest planet away from Earth
 Areas we cover

Sun

Mars Neptune

Jupiter Venus Saturn Mercury

It’s the biggest It’s the second Saturn is a gas giant It’s the closest
planet of them all planet from the Sun and has rings planet to the Sun
A picture is worth a
thousand words
A picture is worth a
thousand words
 A picture always
reinforces
the concept
Images reveal large amounts of
data, so remember: use an image
instead of a long text. Your
audience will appreciate it
A picture always
reinforces
the concept
Images reveal large amounts of
data, so remember: use an image
instead of a long text. Your
audience will appreciate it
 Key accomplishments

Mercury Venus
Mercury is the Venus has a
smallest planet beautiful name

Jupiter Saturn
It’s the biggest Saturn is a gas giant
planet of them all with rings
 Key accomplishments

Mercury Saturn Mars

Mercury is the closest Saturn is a gas giant Despite being red,
planet to the Sun and has rings Mars is a cold place

Jupiter Neptune
Jupiter is the biggest It’s the farthest planet
planet of them all from the Sun
Desktop mockup
You can replace the image on
the screen with your own work
 Tablet mockup
You can replace the image on
the screen with your own work
Phone mockup
You can replace the image on
the screen with your own work
 Patient satisfaction

Gender Results

75% Venus
Venus is the second planet
from the Sun
01
25% Mars
Age Despite being red, Mars is a 02
cold place, not hot

20-35 25% Mercury

36-60 90%
Mercury is the closest planet to
the Sun and the smallest one
03
 Core customers

Gender Age
18 - 35 80%

25% 75% 36 - 60 25%

Interest
25% 50% 90%
Saturn is a gas Mars is actually a Venus has a
giant and has rings cold place, not hot beautiful name
 Testimonial

Jenna Doe, 25 John James, 36

“Mercury the closest “Venus has a beautiful
planet to the Sun and it’s name, but it’s hot, even
only a bit larger than the hotter than Mercury”
Moon”

Fred Blogs, 31 Helena Smith, 58

“Despite being red, Mars is “Saturn is a gas giant,
a cold place, not hot. It’s composed mostly of
full of iron oxide dust” hydrogen and helium”
 Testimonials

Claire Blair John Stone Mike Mills

“Mercury is the “Despite being red, “Jupiter is the
smallest planet” Mars is a cold place” biggest planet”

Bob Charlton Kate Poe Lilly Roberts

“Saturn is a gas giant “Neptune is far away “Venus is the second
and has rings” from Earth” planet from the Sun”
 Quality improvement
measures
Venus Saturn Jupiter Mars

Measure 1

Measure 2

Measure 3

Measure 4
 Schedule

Week 1 Week 2
Task
Mon Tue Wed Thu Fri Mon Tue Wed Thu Fri

Task 1
Task 2
Task 3
Task 4
Awesome
words
Awesome
words
 Innovations

Mercury Venus Mars

Mercury is the closest Venus has a beautiful Despite being red, Mars
planet to the Sun name, but it’s very hot is a cold place
 Innovations

Mercury Saturn
Mercury is the closest Saturn is a gas giant
planet to the Sun and has rings

Mars
Despite being red,
Mars is a cold place
 Location center

Mars
Despite being red,
Mars is a cold
place, not hot

Venus
Venus has a
beautiful name,
but it’s terribly hot
Location center
Mars
Mars is a cold
place, not hot

Jupiter
It’s the biggest
planet of them all

Saturn
Saturn has
several rings
 Awards
Mars
2011-2012 Mars is a cold place,
not hot

Saturn
2015-2016 Saturn is composed
mostly of hydrogen

Venus
2018-2019 Venus has a
beautiful name
 Awards

Project Award Year

Mercury Name of the award 2016

Mars Name of the award 2018

Jupiter Name of the award 2020

Venus Name of the award 2021

 Our team

Jenna Doe John James

You can talk a bit about You can talk a bit about this
this person here person here
 Our team

James Rice Lena Jordan

You can talk a bit about You can talk a bit about
this person here this person here

Anna Grey Peter Miles

You can talk a bit about You can talk a bit about
this person here this person here
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