Topik 2

UJI KELARUTAN JENUH

LKM 1
Data dan Perhitungan Uji Kelarutan Jenuh
a. Persamaan kurva baku parasetamol dalam air
KADAR ABSORBAN
2,030 ppm 0,240
4, 060 ppm 0,365
6,090 ppm 0, 474
8,120 ppm 0,632
10,150 ppm 0,718
12,180 ppm 0,840

Persamaan kurva baku  y = 0,0594 x + 0,123

Kurva Baku Parasetamol Dalam Air
0.9

0.8 f(x) = 0.0593525686136524 x + 0.123133333333333

R² = 0.99629511320337
0.7

0.6
Absorbansi

0.5
Y-Values
0.4 Linear (Y-Values)
0.3

0.2

0.1

0
0 2 4 6 8 10 12 14

Kadar

b. Kadar parasetamol terlarut dalam aquadest

Parasetamol
Waktu (menit) Absorban Kadar (ppm) terlarut
(g/50 ml)
30 0,442 5,370 0,6712
45 0,517 6,632 0,8290
60 0,596 7,962 0,9952
90 0,600 8,030 1,003
Perhitungan :
1. 30 menit
 y=0 ,0594 x+ 0,123
0 , 4 42=0 ,0594 x +0,123
0 , 319=0 ,0594 x
x=5,370 ppm
 V 1. M 1=V 2. M 2
25 mL . 5,370 ppm=0 , 01mL . M 2
M 2=13425 ppm

13425 mg
 13425 ppm=
1L
13425 mg x mg
=
1000 mL 50 mL
x=671 , 25 mg/50 mL
x=0,6712 g/50 mL
2. 45 menit
 y=0 ,0594 x+ 0,123
0 , 517=0 , 0594 x+ 0,123
0 , 394=0 , 0594 x
x=6,632 ppm
 V 1. M 1=V 2. M 2
25 mL . 6,632 ppm=0 ,01 mL . M 2
M 2=16580 ppm

16580 mg
 16580 ppm=
1L
16580 mg x mg
=
1000 mL 50 mL
x=829 mg/50 mL
x=0,8290 g /50 mL
3. 60 menit
 y=0 ,0594 x+ 0,123
0 , 596=0 , 0594 x+ 0,123
 0 , 473=0 , 0594 x
x=7,962 ppm
 V 1. M 1=V 2. M 2
25 mL . 7,962 ppm=0 ,01 mL . M 2
M 2=19905 ppm

19905 mg
 19905 ppm=
1L
19905 mg x mg
=
1000 mL 50 mL
x=995 , 25 mg/50 mL
x=0,9952 g/50 mL
4. 90 menit
 y=0 ,0594 x+ 0,123
0 , 600=0 , 0594 x+ 0,123
0 , 477=0 , 0594 x
x=8,030 ppm
 V 1. M 1=V 2. M 2
25 mL . 8,030 ppm=0 , 01 mL . M 2
M 2=20075 ppm

20075 mg
 20075 ppm=
1L
20075 mg x mg
=
1000 mL 50 mL
x=1003 , 75 mg/50 mL
x=1,003 g/50 mL
c. Grafik hubungan kelarutan parasetamol terhadap waktu

Kurva Kelarutan Parasetamol vs Waktu

1.2
1 f(x) = 0.00540609523809524 x + 0.570457142857143
R² = 0.771672889477255
0.8
Kelarutan

0.6 Y-Values
Linear (Y-Values)
0.4
0.2
0
20 30 40 50 60 70 80 90 100

Waktu