1. Osteosarcoma
Metafisis femur distal, tibia
proximal, humerus proximal
Lesi permeatif tulang panjang
bagian metafise
Reaksi periosteal: sun ray,
segitiga Codman
Pembengkakan jaringan lunak
sekitar lesi
Penderita membutuhkan terapi
operatif berupa amputasi.
Selain terapi operatif pada
penderita diperukan terapi
adjuvant berupa pemberian
kemoterapi dan radioterapi
• 1-30 th:
– Ewing Sarcoma
– Osteosarcoma
• 30-40 th:
– Fibrosarcoma dan
malignant fibrous
histiocytoma
– Giant cell tumor ganas
– Reticulum cell sarcoma
– Parosteal sarcoma 2. Ewing sarcoma
Tulang panjang dari
ekstremitas bawah (femur,
tibia, tibula)
Endothelioma tulang
Lesi permeatif di diafise
Reaksi periost onion skin
Fraktur patologis 5 %
Tumor tulang yang sering
metastase ke tulang
dibandingkan tumor tulang lain
Sensitif terhadap radioterapi 4. Giant cell tumor/osteoklastoma
tetapi tidak curable Lesi di metafise meluas
Kemoterapi lebih efektif kearah subartikuler pada
epifise sudah menutup
daripada radioterapi
Lesi lusen eksentris
Sifat ekspansif dengan soap
bubble appearance
Kadang–kadang sulit
membedakan antara jinak dan
ganas
3. Fibrosarcoma
Lesi: medulare (sentral),
periosteal
Lesi destruksi medular (litik)
eksentris
Pembengkakan jaringan lunak
lebih hebat dari tulang
Segitiga Codman bisa terjadi
5. Parosteal sarkoma
tapi jarang
Menjalar ke sistem limfatik
Tumbuh sangat lambat (beda
dengan sentral osteo sa)
Usia: 30 – 40 / 50 th
Sangat radioopak, homogen,
juxtacortical
Sering di fossa poplitea femur
10. Chondroma
Chondromas are usually
asymptomatic and are
discovered incidentally on x-ray
or after a pathological fracture
X-ray shows a well-defined,
centrally placed radiolucent
area at the junction of
metaphysis and diaphysis;
sometimes the bone is slightly
expanded.
In mature lesions there are
flecks or wisps of calcification
within the lucent area; when
present, this is a
pathognomonic feature.
12. Osteokondroma
11. Chondroblastoma
Pain due to an overlying bursa
X-ray shows a rounded, well
or impingement on soft tissues,
demarcated radiolucent area in
or, rarely, paraesthesia due to
the epiphysis with no hint of
stretching of an adjacent nerve
central calcification; this site is
The x-ray appearance is
so unusual that the diagnosis
pathognomonic. There is a well-
springs readily to mind.
defined exostosis emerging
Sometimes the lesion extends
from the metaphysis, its base co
across the physeal line.
extensive with the parent bone.
The articular surface is
It looks smaller than it feels
breached.
because the cartilage cap is
Like osteoblastoma, the lesion
usually invisible on x-ray large
sometimes expands and
lesions undergo cartilage
acquires the features of an
degeneration and calcification
aneurysmal bone cyst
the x-ray shows the bony
Histologic cobblestone
exostosis surrounded by clouds
Radiologic chicken wire
of calcified material
calcification
METABOLIC DISEASE
PEDIATRIC