S2 2017 387433 Tableofcontent

VALIDASI 8-ITEM MORISKY MEDICATION ADHERENCE SCALE VERSI INDONESIA PADA PASIEN
DIABETES MELITUS TIPE

2 DI PUSKESMAS KABUPATEN SLEMAN DAN KOTA YOGYAKARTA
LITA RIASTIENANDA P, Prof. Zullies Ikawati, Ph.D., Apt;Dr. Dwi Endarti, M.Sc.,Apt
Universitas Gadjah Mada, 2017 | Diunduh dari http://etd.repository.ugm.ac.id/
DAFTAR ISI
HALAMAN JUDUL........................................................................................ i
HALAMAN PENGESAHAN .......................................................................... ii
PERNYATAAN ............................................................................................... iii
KATA PENGANTAR ..................................................................................... iv
DAFTAR ISI .................................................................................................... vii
DAFTAR GAMBAR ....................................................................................... ix
DAFTAR TABEL ............................................................................................ x
DAFTAR LAMPIRAN .................................................................................... xi
INTISARI......................................................................................................... xiii
ABSTRACT ..................................................................................................... xiv
BAB I PENDAHULUAN ................................................................................ 1
A. Latar Belakang Penelitian........................................................................ 1
B. Perumusan Masalah ................................................................................. 4
C. Keaslian Penelitian .................................................................................. 5
D. Manfaat Penelitian ................................................................................... 7
E. Tujuan Penelitian ..................................................................................... 7
BAB II TINJAUAN PUSTAKA...................................................................... 8
A. Telaah Pustaka ......................................................................................... 8
1. Kepatuhan ............................................................................................. 8
2. Diabetes Mellitus .................................................................................. 14
3. Morisky Medication Adherence Scale................................................... 27
4. Psychometric Properties ....................................................................... 29
B. Landasan Teori ........................................................................................ 35
C. Kerangka Konsep Penelitian.................................................................... 37
D. Keterangan Empiris ................................................................................. 37
BAB III METODOLOGI PENELITIAN......................................................... 38
A. Rancangan Penelitian .............................................................................. 38
B. Lokasi Penelitian ..................................................................................... 38
C. Populasi dan Sampel penelitian ............................................................... 39
iii
D. Definisi Operasional Variabel Penelitian ................................................ 40

E. Instrumen Penelitian ................................................................................ 41
F. Jalannya Penelitian ................................................................................... 44
G. Analisis Data ........................................................................................... 49
BAB IV HASIL DAN PEMBAHASAN ......................................................... 55
A. Data demografi dan karakteristik subjek penelitian ............................... 55
B. Kepatuhan Pasien Diabetes Mellitus Tipe 2 ........................................... 58
C. Psychometric properties ......................................................................... 65
1. Uji Reliabilitas .................................................................................... 65
a. Internal Consistency Cronbach Alpha ........................................... 65
b.Test-retest ........................................................................................ 67
2. Uji Validitas ........................................................................................ 70
a. Convergent validity ........................................................................ 70
b. Known group validity..................................................................... 71
D. Sensitivitas dan spesifisitas .................................................................... 73
E. Keterbatasan Penelitian ........................................................................... 78
BAB V KESIMPULAN DAN SARAN ........................................................... 79
1. Kesimpulan .............................................................................................. 79
2. Saran ........................................................................................................ 80
DAFTAR PUSTAKA ...................................................................................... 81
RINGKASAN TESIS ...................................................................................... 131
SUMMARY ....................................................................................................... 132
NASKAH PUBLIKASI ................................................................................... 133
iv
DAFTAR GAMBAR
Gambar 1. Kerangka Konsep Penelitian .......................................................... 37

Gambar 2. Skema Penelitian ............................................................................ 44
Gambar 3. Alur translasi MMAS-8item dan MMAS-4item ............................ 47
v
DAFTAR TABEL
Tabel 1. Keaslian Penelitian .......................................................................... 5

Tabel 2. Metode pengukuran kepatuhan ............................................... ........ 12
Tabel 3. Kriteria diagnosis diabetes ............................................................... 19
Tabel 4. Kuesioner MMAS-8item original.................................................... 42
Tabel 5. Kuesioner MMAS-4item original.................................................... 43
Tabel 6. Kuesioner MMAS 8 item versi Indonesia........................................ 48
Tabel 7. Kuesioner MMAS 4 item versi Indonesia........................................ 49
Tabel 8. Penilaian kuesioer MMAS-8item..................................................... 49
Tabel 9. Penilaian kuesioer MMAS-4item..................................................... 50
Tabel 10. Rumus perhitungan sensitivitas, spesifisitas, prediktif positif
value dan prediktif negatif value...................................................... 53
Tabel 11. Karakteristik umum subjek penelitian ............................................. 55
Tabel 12. Karakteristik subjek terhadap kategori kepatuhan ........................... 60
Tabel 13. Hasil Cronbach Alpha...................................................................... 66
Tabel 14. Hasil test retest berdasarkan kategori tingkat kepatuhan ................. 68
Tabel 15. Skor Test Retest waktu pertama dan kedua...................................... 69
Tabel 16. Kategori tingkat kepatuhan MMAS 8 item dan MMAS 4item
versi Indonesia ................................................................................. 70
Tabel 17. Hubungan antara kategori tingkat kepatuhan dan kadar glukosa
MMAS 8item versi Indonesia.......................................................... 72
Tabel 18. Hubungan antara kategori tingkat kepatuhan dan kadar glukosa
MMAS 4item versi Indonesia.......................................................... 72
Tabel 19. Hasil sensitivitas, spesifisitas, prediktif positif value dan
prediktif negatif value MMAS 8item versi Indonesia ..................... 74
Tabel 20. Hasil sensitivitas, spesifisitas, prediktif positif value dan
prediktif negatif value MMAS 4item versi Indonesia ..................... 74
6
DAFTAR LAMPIRAN
Lampiran 1. Lembar Informed Consent ......................................................... 86

Lampiran 2. Lembar Informasi Pasien ........................................................... 87
Lampiran 3. Kuesioner MMAS-8 (Morisky Medication Adherence
Scale-8 items) original ............................................................... 89
Lampiran 4. Kuesioner MMAS-4item original ............................................. 90
Lampiran 5. Kuesioner MMAS 8 item versi Indonesia ................................. 91
Lampiran 6. Kuesioner MMAS 4 item versi Indonesia ................................. 92
Lampiran 7. Data kategori kepatuhan pasien dan skor MMAS
8item versi Indonesia ................................................................ 93
Lampiran 8. Hasil Cronbach Alpha ............................................................... 104
Lampiran 9. Hasil uji normalitas MMAS 8 item dan MMAS 4item ............. 105
Lampiran 10. Hasil Test Retest berdasarkan kategori kepatuhan
pasien dan skor kuesioner ........................................................ 106
Lampiran 11. Hasil Covergent Validity ........................................................... 107
Lampiran 12. Hasil Known group validity MMAS 8item ............................... 108
Lampiran 13. Hasil Known group validity MMAS 4item ............................... 109
Lampiran 14. Hasil Test Retest berdasarkan kategori kepatuhan
pasien diabetes mellitus tipe 2 ................................................. 110
Lampiran 15. Data test retest berdasarkan skor waktu 1 dan waktu 2 ............. 112
Lampiran 16. Hasil spss karakteristik umum pasien........................................ 113
Lampiran 17. Hasil spss hubungan karakteristik umum pasien dengan
kategori kepatuhan ................................................................. 115
Lampiran 18. Pengantar Etichal Clearance ..................................................... 124
Lampiran 19. Ethical clearance ...................................................................... 125
Lampiran 20. Surat Rekomendari izin penelitian dari Dinas
Perizinan Kota Yogyakarta....................................................... 126
Lampiran 21. Surat Rekomendari izin penelitian dari Dinas
Kesehatan Kota Yogyakarta ..................................................... 127
Lampiran 22. Surat Rekomendasi Penelitian dari Bappeda Sleman ................ 128
7
Lampiran 23. Surat Keterangan Selesai Penelitian .......................................... 129

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VALIDASI 8-ITEM MORISKY MEDICATION ADHERENCE SCALE VERSI INDONESIA PADA PASIEN

DIABETES MELITUS TIPE

D. Definisi Operasional Variabel Penelitian ................................................ 40

Gambar 1. Kerangka Konsep Penelitian .......................................................... 37

Tabel 1. Keaslian Penelitian .......................................................................... 5

Lampiran 1. Lembar Informed Consent ......................................................... 86

Lampiran 23. Surat Keterangan Selesai Penelitian .......................................... 129

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