SEDIAAN SEMI

SOLID

Dosen pengampu ;

HALIMAHTUSA'DIYAH, S.Farm., M.Kes., Apt

 Kelompok 8
01 Iradat Gustiani 04 Tiya Putri Andani

02 Syefia Ulandari 05 Dwi Sanira

03 Mutma Regina 06 Muhammad Ilham

 Pengertian
Sediaan semi solid adalah sediaan setengah
padat yang digunakan untuk pemakaian luar
yang ditujukan untuk aplikasi pada kulit
untuk mencapai efek lokal dan kadang-kadang
efek sistemik.
 Salah satu sifat sediaan semisolid adalah mampu
melekat pada permukaan tempat pemakaian dalam
waktu yang cukup lama sebelum sediaan dicuci
atau dihilangkan.
 Pelekatan ini disebabkan oleh sifat rheologis dari
sediaan yang memungkinkan sediaan semisolid
tersebut bentuknya tetap dan melekat sebagai
lapisan tipis sampai ada tindakan yang
mengakibatkan sediaan semisolid akan rusak
bentuknya dan mengalir.
 Sifat fisik sediaan tergantung pada beberapa
faktor, termasuk ukuran partikel terdispersi,
tegangan antarmuka diantara fase, koefisien
partisi bahan aktif diantara fase, dan rheologi
produk.
 Salep
 Menurut FI. ed III, salep adalah sediaan semi padat
yang mudah dioleskan dan digunakan sebagai obat
luar.

https://youtu.be/hg6y4yAEhLg
 Menurut FI.ed IV, salep adalah sediaan setengah
padat ditunjukan untuk pemakaian topikal pada
kulit atau selaput lendir.

 Salep tidak boleh berbau tengik. Kecuali dinyatakan

lain kadar bahan obat dalam salep mengandung
obat keras atau narkotika adalah 10%.
 Menurut DOM, Salep adalah sediaan semi padat
dermatologis yang menunjukkan aliran dilatan yang
penting.

 Menurut Scoville’s, ;salep terkenal pada daerah

dermatologi dan tebal, salep kental dimana pada
dasarnya tidak melebur pada suhu tubuh, sehingga
membentuk dan menahan lapisan pelindung pada area
dimana pasta digunakan.
 Menurut Formularium nasional ; salep adalah
sediaan berupa massa lembek, mudah dioleskan,
umumnya lembek dan mengandung obat,
digunakan sebagai obat luar untuk melindungi
atau melemaskan kulit, tidak berbau tengik.
 Fungsi salep

Salep biasanya digunakan sebagai :

•Bahan pembawa substansi obat untuk pengobatan
kulit.
•Bahan pelumas pada kulit.
•Pelindung untuk kulit yaitu mencegah kontak
permukaan kulit dengan larutan berair dan rangsang
kulit
 Salep memiliki kriteria sebagai berikut :
1.Aman (tidak toksik, tidak iritatif)
2.Efektif dan efisien
3.Stabil dalam penyimpanan
4.Basis salep mampu membawa zat aktif dan
melepaskannya pada tempat aksi
5.Memiliki viskositas dan daya sebar sedemikian rupa
Sehingga mudah dikeluarkan dari kemasan mudah
dioleskan secara merata.
 Dasar salep

 Dasar Salep
Menurut FI Ed IV, dasar salep yang digunakan
sebagai pembawa dibagi dalam 4 kelompok, yaitu
dasar salep senyawa hidrokarbon,dasar salep
serap,dasar salep yang dapat dicuci dengan air,
dasar salep larut dalam air.
 01
PRESENTATION
You can enter a subtitle here if you need it
 AIR FLOW AND GAS EXCHANGE

GAS EXCHANGE AIR FLOW

Mercury is the closest planet to the Venus has a beautiful name and is the
Sun and the smallest one in the Solar second planet from the Sun. It’s hot
System—it’s only a bit larger than the and has a poisonous atmosphere
Moon
 RISK FACTORS

MARS
Despite being red, Mars is a
cold place

VENUS
Venus is the second planet
from the Sun

Follow the link in the graph to modify its data and then paste the new one here.
For more info, click here
ASTHMA AND POLLUTION

51%
Saturn is a gas giant and has rings

37%
Mars is actually a very cold place

28%
Mercury is the closest planet to the Sun
REASONS TO CELEBRATE THE DAY

MARS
Despite being red, Mars is a cold place. The
planet is full of iron oxide dust

MERCURY
Mercury is the closest planet to the Sun and the
smallest in Solar System

EARTH
Earth is the only planet known to harbor life. It’s
known as the blue planet
A PICTURE IS WORTH A
THOUSAND WORDS
 PURPOSES OF CELEBRATION

AWARENESS PREVENTIONS
Venus is the second planet Jupiter is the biggest planet
from the Sun of them all

INFORMATION METHODS
Despite being red, Mars is a Saturn is a gas giant and has
cold place several rings
 MOST USED DIAGNOSIS METHODS

32% 54% 78%

SPIROMETRY CHEST X-RAY BLOOD TEST

Despite being red, Mars Saturn is a gas giant and Venus is the second
is a cold place has several rings planet from the Sun
 COMMON SYMPTOMS

COUGH FATIGUE DYSPNEA

Mercury is the closest planet Venus is the second planet Mars is actually a very cold
to the Sun from the Sun place

WHEEZING SWELLING MOCUS

Jupiter is the biggest planet Saturn is composed of Neptune is the farthest planet
of them all hydrogen and helium from the Sun
A PICTURE
ALWAYS
REINFORCES THE
CONCEPT
Images reveal large amounts of data, so
remember: use an image instead of a long text.
Your audience will appreciate it
“This is a quote, words full of wisdom that
someone important said and can make the
reader get inspired.”
—SOMEONE FAMOUS
 OUR TEAM

JENNA SUE MARK CAYTON

Neptune is the farthest planet from Despite being red, Mars is a very cold
the Sun place
WHAT EXPERTS SAY ABOUT THIS DAY

DAVID SMITH SARAH ROY

“Venus is the second planet “Jupiter is the biggest planet of
from the Sun” them all”

LAURA MATTS PETER STUART

“Despite being red, Mars is a “Saturn is a gas giant and has
cold place” several rings”
MOST AFFECTED COUNTRIES

MARS
Despite being red, Mars is a
cold place

VENUS
Venus is the second planet
from the Sun

SATURN
Saturn is a gas giant and has
several rings
AWESOME
WORDS
 SECONDARY EFFECTS OF ASTHMA
40% 26%
PNEUMONIA
Despite being red, Mars is a
cold place

LUNG CANCER
Venus is the second planet
from the Sun

DEPRESSION 34%
Saturn is a gas giant and has Follow the link in the graph to modify its data and
several rings then paste the new one here.
For more info, click here
 WHAT TO DO IN AN ASTHMA CRISIS

01 03
STAY CALM USE INHALER
Despite being red, Mars 02 Venus has a beautiful 04
is a cold place name

SIT DOWN DIAL 911

Mercury is a very small Neptune is far away
planet from us
 HOW TO HELP IN AN ASTHMA CRISIS

PERSON WITH CRISIS

NEPTUNE SATURN

MERCURY JUPITER VENUS MARS

It’s the closest planet to It’s a gas giant and the Venus has a beautiful Mars is actually a very
the Sun biggest planet name cold place
 ASTHMA FACTS AND MYTHS
STATEMENT MYTHS FACTS
Mercury is a small planet

Saturn is a gas giant and has rings

Jupiter is the biggest planet

Neptune is far away from us

Mars is actually a very cold place

150,000
Big numbers catch your audience’s attention
 PATIENT PROFILE
HABITS
Smokers 4/5
Genes 3/5
Infections 2/5

AGE RANGE
31% 69% 15% 35-45

WOMEN MEN 25% 46-55

Venus has a beautiful Despite being red, Mars
name is cold 60% 56-65
ASTHMA AIR FLOW EXPLANATION
HEALTHY AIRWAY
Despite being red, Mars is a cold place

HEALTHY ALVEOLI
Mercury is the closest planet to the Sun

CHRONIC BRONCHITIS
Jupiter is the biggest planet of them all

EMPHYSEMA
Neptune is very far away from Earth
 ASTHMA LUNG CHARACTERISTICS

NORMAL LUNGS LUNGS WITH COPD

Mercury is the closest planet to the Sun and the Despite being red, Mars is actually a cold
smallest of them all place. It’s full of iron oxide dust

Healthy airway Healthy alveoli Chronic bronchitis Emphysema

 HEALTHY AIRWAY
SMOOTH MUSCLE HEALTHY ALVEOLI
Mercury the closest planet to Venus is the second planet from
the Sun the Sun

OPEN AIRWAY NORMAL TUBE

Despite being red, Mars is a Jupiter a gas giant and the
cold place biggest planet
 ASTHMA PREVENTIONS
BREATH EXERCISE
Jupiter is the biggest planet of them
all

HEALTHY WEIGHT
Saturn is composed of hydrogen and
helium

QUIT SMOKING
Neptune is the farthest planet from
the Sun
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