DAFTAR ISI

HALAMAN

HALAMAN JUDUL .......................................................................................... ii

ABSTRAK……………………………………………………………………….iii

ABSTRACT……………………………………………………………………………..iv
HALAMAN PERSETUJUAN…………………………………………………..v

HALAMAN PENGESAHAN…………………………………………………..vi
SURAT PERNYATAAN KEASLIAN………………………………………...vii
PERSETUJUAN PUBLIKASI………………………………………………..viii
PEDOMAN PENGGUNAAN SKRIPSI……………………………………….ix
RIWAYAT HIDUP………………………………………………………………x
MOTTO………………………………………………………………………….xi
HALAMAN PERSEMBAHAN………………………………………………..xii
KATA PENGANTAR………………………………………………………….xiii
DAFTAR ISI ................................................................................................... xvi

DAFTAR TABEL ............................................................................................ xx

DAFTAR GAMBAR ....................................................................................... xxi
DAFTAR LAMPIRAN .................................................................................. xxii
DAFTAR SINGKATAN DAN ISTILAH……………………………..…….xxiii
BAB I. PENDAHULUAN .................................................................................. 1
A. Latar Belakang ......................................................................................... 1

B. Rumusan Masalah .................................................................................... 3

C. Tujuan Penelitian ..................................................................................... 4

1. Tujuan Umum .................................................................................... 4
2. Tujuan Khusus.................................................................................... 4

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 D. Manfaat Penelitian.................................................................................... 4
1. Manfaat Teoritis ................................................................................. 4
2. Manfaat Praktis .................................................................................. 4

BAB II. TINJAUAN PUSTAKA ....................................................................... 6

A. Tinjauan Pustaka ...................................................................................... 6

1. Definisi Diabetes Melitus ................................................................... 6
2. Klasifikasi Diabetes Melitus ............................................................... 6
3. Patofisiologi Diabetes Melitus ............................................................ 7
4. Gejala Diabetes Melitus ...................................................................... 8
5. Diagnosis Diabetes Melitus ............................................................... 8
6. Penyebab Diabetes Melitus ................................................................. 9
7. Penatalaksanaan Diabetes Melitus .................................................... 10
a. Terapi Farmakologi………………………………………………10
b. Terapi Non Farmakologi…………………………………………14
8. Algoritma Tatalaksana Diabetes Melitus ........................................... 15

B. Farmakovigilans .................................................................................... 16

1. Pengertian Farmakovigilans ............................................................. 16

2. Tujuan Farmakovigilans ................................................................... 16
C. ADR (Adverse Drug Reaction) .............................................................. 17
D. Meso ..................................................................................................... 17
E. Interaksi Obat ......................................................................................... 20
1. Defenisi Interaksi Obat…………………………………………..20
2. Mekanisme Interaksi Obat……………………………………….20
F. Rekam Medis ......................................................................................... 22
G. Penggolongan Usia ................................................................................. 23
H. Rumah Sakit ........................................................................................... 24
1. Pengertian Rumah Sakit.................................................................... 24
2. Klasifikasi Rumah Sakit ................................................................... 24
3. Fungsi Rumah Sakit.......................................................................... 24
4. Standar Pelayanan Kefarmasian Rumah Sakit ................................... 25
I. Kerangka Teori…………………………………………………………...29

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 J. Kerangka Konsep………………………………………………………...30

BAB III. METODE PENELITIAN ................................................................. 31

A. Instrumen Penelitian ............................................................................... 31

B. Prosedur Penelitian ................................................................................. 31
1. Tahap Persiapan ............................................................................... 31
2. Tahan Penatalaksanaan ..................................................................... 32
3. Tahap Pengolahan ............................................................................ 32
4. Tahap Akhir ..................................................................................... 34
C. Teknik Pengumpulan dan Analisis Data ......................................................34
D. Rencana Penelitian……………………………………………………….35
1. Prinsip Penelitian…………………………………………………….35
2. Populasi , Sampel, dan Metode Pengambilan Sampel……………….35
3. Waktu dan Tempat Penelitian………………………………………..36
4. Variabel Penelitian…………………………………………………...36
5. Definisi Operasional………………………………………………….37
E. Analisa Data……………………………………………………………...37
F. Etika Penelitian ...................................................................................... 38
G. Jadwal Kegiatan Penelitian………………………………………………38

BAB IV HASIL DAN PEMBAHASAN……………………………………….39

A. Profil Rumah Sakit……………………………………………………….39

1. Sejarah Rumah Sakit…………………………………………………39
2. Visi, Misi, dan Motto Rumah Sakit………………………………….40
3. Instalasi Farmasi Rumah Sakit……………………………………….41
4. Tenaga Kefarmasian………………………………………………….42
5. Pengambilan Sampel…………………………………………………42
6. Karakteristik Berdasarkan Jenis Kelamin……………………………42
7. Karakteristik Berdasarkan Usia……………………………………....43
8. Efek Samping Obat…………………………………………………..44
9. Analisis Interaksi Obat……………………………………………….49

BAB V KESIMPULAN DAN SARAN………………………………………..50

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 A. Kesimpulan………………………………………………………………50
B. Saran ……………………………………………………………………..50

DAFTAR PUSTAKA ....................................................................................... 51

LAMPIRAN……………………………………………………………………..55

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